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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of secondary heart field cardioblast proliferation
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Accession:GO:0003266 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).
Synonyms:exact_synonym: regulation of SHF cardioblast proliferation;   regulation of second heart field cardioblast proliferation


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regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
RGD:1600115
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
positive regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
RGD:1600115
G Gng5 G protein subunit gamma 5 JBrowse link 2 252,359,976 252,368,473 RGD:1624291
G Six1 SIX homeobox 1 JBrowse link 6 95,929,060 95,934,296 RGD:1624291
RGD:1600115
G Tbx1 T-box transcription factor 1 JBrowse link 11 86,552,022 86,561,647 RGD:1624291
G Tbx5 T-box transcription factor 5 JBrowse link 12 42,059,688 42,148,226 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    cell population proliferation 2108
      cell proliferation involved in heart morphogenesis 23
        regulation of cell proliferation involved in heart morphogenesis 21
          regulation of cardioblast proliferation 12
            regulation of secondary heart field cardioblast proliferation 11
              BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation 0
              Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
              fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation 0
              positive regulation of secondary heart field cardioblast proliferation + 5
              smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
Path 2
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      anatomical structure development 6063
        multicellular organism development 5534
          system development 5081
            animal organ development 3881
              heart development 684
                heart morphogenesis 281
                  heart formation 31
                    cardioblast proliferation 12
                      regulation of cardioblast proliferation 12
                        regulation of secondary heart field cardioblast proliferation 11
                          BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation 0
                          Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
                          fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation 0
                          positive regulation of secondary heart field cardioblast proliferation + 5
                          smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.