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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
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Accession:GO:0003271 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
Synonyms:exact_synonym: hedgehog signaling pathway involved in regulation of second heart field cardioblast proliferation;   hh signaling pathway involved in regulation of second heart field cardioblast proliferation;   smoothened receptor signaling pathway involved in regulation of second heart field cardioblast proliferation;   smoothened receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation;   smoothened receptor signalling pathway involved in regulation of secondary heart field cardioblast proliferation


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smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1600115
RGD:1624291

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Path 1
Term Annotations click to browse term
  biological_process 19676
    cellular process 18449
      signal transduction 6946
        cell surface receptor signaling pathway 2759
          smoothened signaling pathway 160
            smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
Path 2
Term Annotations click to browse term
  biological_process 19676
    developmental process 6727
      anatomical structure development 6175
        multicellular organism development 5632
          system development 5208
            animal organ development 3969
              animal organ morphogenesis 1134
                heart morphogenesis 278
                  cell proliferation involved in heart morphogenesis 23
                    cardioblast proliferation 12
                      regulation of cardioblast proliferation 12
                        regulation of secondary heart field cardioblast proliferation 11
                          smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.