ONTOLOGY REPORT - ANNOTATIONS


Term:endocardial cushion formation
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Accession:GO:0003272 term browser browse the term
Definition:The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.


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endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
RGD:1600115
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
G Robo2 roundabout guidance receptor 2 JBrowse link 11 11,062,866 12,618,793 RGD:1624291
G Tbx20 T-box 20 JBrowse link 8 25,849,394 25,904,570 RGD:1624291
RGD:1600115
cell migration involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dchs1 dachsous cadherin-related 1 JBrowse link 1 170,594,981 170,629,062 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Heyl hes-related family bHLH transcription factor with YRPW motif-like JBrowse link 5 140,923,914 140,940,905 RGD:1624291
RGD:1600115
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
RGD:1600115
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
RGD:1600115
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Tmem100 transmembrane protein 100 JBrowse link 10 77,537,340 77,543,710 RGD:1624291
RGD:1600115
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
RGD:1600115
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    developmental process 6323
      anatomical structure formation involved in morphogenesis 1168
        endocardial cushion formation 27
          cell migration involved in endocardial cushion formation 4
          epithelial to mesenchymal transition involved in endocardial cushion formation + 20
Path 2
Term Annotations click to browse term
  biological_process 17896
    developmental process 6323
      anatomical structure development 5930
        multicellular organism development 5425
          system development 5004
            animal organ development 3820
              mesenchyme development 279
                endocardial cushion development 49
                  endocardial cushion morphogenesis 37
                    endocardial cushion formation 27
                      cell migration involved in endocardial cushion formation 4
                      epithelial to mesenchymal transition involved in endocardial cushion formation + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.