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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Wnt signaling pathway involved in heart development
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Accession:GO:0003308 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
Synonyms:exact_synonym: negative regulation of Wnt receptor signaling pathway involved in heart development;   negative regulation of Wnt receptor signalling pathway involved in heart development;   negative regulation of Wnt-activated signaling pathway involved in heart development


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negative regulation of Wnt signaling pathway involved in heart development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alpk2 alpha-kinase 2 JBrowse link 18 60,960,009 61,072,116 RGD:1600115
RGD:1624291
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Sox17 SRY-box transcription factor 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
RGD:1600115
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      negative regulation of developmental process 1087
        negative regulation of Wnt signaling pathway involved in heart development 6
          negative regulation of canonical Wnt signaling pathway involved in heart development + 1
          negative regulation of planar cell polarity pathway involved in heart morphogenesis + 1
          positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 19245
    biological regulation 13198
      regulation of biological process 12516
        regulation of cellular process 11839
          signal transduction 6837
            cell surface receptor signaling pathway 2647
              cell surface receptor signaling pathway involved in cell-cell signaling 554
                Wnt signaling pathway 434
                  Wnt signaling pathway involved in heart development 13
                    regulation of Wnt signaling pathway involved in heart development 8
                      negative regulation of Wnt signaling pathway involved in heart development 6
                        negative regulation of canonical Wnt signaling pathway involved in heart development + 1
                        negative regulation of planar cell polarity pathway involved in heart morphogenesis + 1
                        positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.