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ONTOLOGY REPORT - ANNOTATIONS


Term:pancreatic A cell fate commitment
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Accession:GO:0003326 term browser browse the term
Definition:The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.


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pancreatic A cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 ISO MGI:MGI:97347 (MGI:MGI:3768695|PMID:17988662) RGD PMID:17988662 MGI:MGI:3768695 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
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G Nkx2-2 NK2 homeobox 2 ISO MGI:MGI:1339708|MGI:MGI:1932100 (MGI:MGI:3703458|PMID:17202186), (MGI:MGI:3768695|PMID:17988662) RGD PMID:17202186, PMID:17988662 MGI:MGI:3703458, MGI:MGI:3768695 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    developmental process 6813
      cellular developmental process 4445
        cell fate commitment 289
          epithelial cell fate commitment 17
            pancreatic A cell fate commitment 2
Path 2
Term Annotations click to browse term
  biological_process 20015
    developmental process 6813
      anatomical structure development 6257
        tissue development 2094
          epithelium development 1257
            epithelial cell differentiation 707
              columnar/cuboidal epithelial cell differentiation 154
                glandular epithelial cell differentiation 59
                  enteroendocrine cell differentiation 33
                    pancreatic A cell differentiation 9
                      pancreatic A cell fate commitment 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.