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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA clamp loader activity
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Accession:GO:0003689 term browser browse the term
Definition:Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
Synonyms:exact_synonym: DNA clamp loading ATPase activity
 narrow_synonym: PCNA loading activity;   PCNA loading complex activity
 xref: reactome:R-HSA-176264 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"


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DNA clamp loader activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chtf18 chromosome transmission fidelity factor 18 JBrowse link 10 15,090,762 15,098,825 RGD:1624291
G Chtf8 chromosome transmission fidelity factor 8 JBrowse link 19 39,077,580 39,087,880 RGD:1624291
RGD:1600115
G Dscc1 DNA replication and sister chromatid cohesion 1 JBrowse link 7 94,759,076 94,774,787 RGD:1624291
RGD:13792537
G Rad17 RAD17 checkpoint clamp loader component JBrowse link 2 30,634,353 30,664,618 RGD:13792537
G Rfc1 replication factor C subunit 1 JBrowse link 14 44,627,528 44,702,205 RGD:1600115
G Rfc2 replication factor C subunit 2 JBrowse link 12 25,130,375 25,143,480 RGD:1624291
RGD:13792537
RGD:1600115
G Rfc3 replication factor C subunit 3 JBrowse link 12 1,460,581 1,471,344 RGD:1624291
RGD:13792537
G Rfc4 replication factor C subunit 4 JBrowse link 11 81,358,592 81,373,044 RGD:1624291
RGD:13792537
G Rfc5 replication factor C subunit 5 JBrowse link 12 44,931,494 44,941,051 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19528
    binding 15911
      organic cyclic compound binding 5784
        nucleic acid binding 3636
          DNA binding 2000
            DNA clamp loader activity 9
Path 2
Term Annotations click to browse term
  molecular_function 19528
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on acid anhydrides 858
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 856
            pyrophosphatase activity 854
              nucleoside-triphosphatase activity 792
                ATPase activity 435
                  ATPase activity, coupled 276
                    DNA-dependent ATPase activity 103
                      protein-DNA loading ATPase activity 9
                        DNA clamp loader activity 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.