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ONTOLOGY REPORT - ANNOTATIONS


Term:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
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Accession:GO:0003831 term browser browse the term
Definition:Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.
Synonyms:narrow_synonym: thyroid galactosyltransferase activity;   thyroid glycoprotein beta-galactosyltransferase
 related_synonym: GalT activity;   UDP-galactose--glycoprotein galactosyltransferase activity;   UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity;   UDPgalactose-glycoprotein galactosyltransferase activity;   UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity;   beta-N-acetyl-beta-1,4-galactosyltransferase activity;   glycoprotein 4-beta-galactosyl-transferase activity;   glycoprotein 4-beta-galactosyltransferase activity;   glycoprotein beta-galactosyltransferase activity;   uridine diphosphogalactose-glycoprotein galactosyltransferase activity
 xref: EC:2.4.1.38;   MetaCyc:2.4.1.38-RXN;   RHEA:22932;   Reactome:R-HSA-3656230 "Defective B4GALT1 does not transfer Gal to the keratan chain";   Reactome:R-HSA-4793956 "Defective B4GALT1 does not add Gal to N-glycan";   Reactome:R-HSA-9035949 "Defective B4GALT1 does not transfer Gal to the N-glycan precursor";   Reactome:R-HSA-9035950 "Defective B4GALT1 does not transfer Gal to a branch of keratan";   reactome:R-HSA-1912352 "Galactosylation of Pre-NOTCH";   reactome:R-HSA-2025723 "B4GALTs transfer Gal to the N-glycan precursor";   reactome:R-HSA-2046265 "B4GALTs transfer Gal to the keratan chain";   reactome:R-HSA-2046298 "B4GALTs transfer Gal to a branch of keratan";   reactome:R-HSA-975919 "Addition of galactose by beta 4-galactosyltransferases"


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beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt1 beta-1,4-galactosyltransferase 1 IEA
ISO
GO_REF:0000107
MGI:2178779|MGI:2388614|MGI:2450889 (MGI:1203321|PMID:9588205), (MGI:1290117|PMID:9813328), (MGI:1339510|PMID:10381349), (MGI:2178150|PMID:11900463), (MGI:5824792|PMID:27553271), (MGI:75839|PMID:7641815), (MGI:84206|PMID:8787759), (MGI:85242|PMID:9013935), (MGI:87365|PMID:9155011)
(PMID:16157350), (PMID:33805)
Ensembl
RGD
PMID:33805, PMID:7641815, PMID:8787759, PMID:9013935, PMID:9155011, PMID:9588205, PMID:9813328, PMID:10381349, PMID:11900463, PMID:16157350, PMID:27553271 GO_REF:0000107, MGI:1203321, MGI:1290117, MGI:1339510, MGI:2178150, MGI:5824792, MGI:75839, MGI:84206, MGI:85242, MGI:87365 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr13:89,643,847...89,649,880
Ensembl chr13:89,643,881...89,649,906
JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 ISO (PMID:24052259) RGD PMID:24052259 NCBI chr17:9,549,605...9,558,672
Ensembl chr17:9,550,028...9,558,634
JBrowse link
G Wdfy3 WD repeat and FYVE domain containing 3 ISO (MGI:86669|PMID:9108238) RGD PMID:9108238 MGI:86669 NCBI chr14:9,169,409...9,384,835
Ensembl chr14:9,141,512...9,381,870
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    catalytic activity 6065
      transferase activity 2352
        transferase activity, transferring glycosyl groups 281
          UDP-glycosyltransferase activity 145
            UDP-galactosyltransferase activity 25
              beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity 4
Path 2
Term Annotations click to browse term
  molecular_function 20457
    catalytic activity 6065
      transferase activity 2352
        transferase activity, transferring glycosyl groups 281
          transferase activity, transferring hexosyl groups 200
            galactosyltransferase activity 28
              UDP-galactosyltransferase activity 25
                beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.