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ONTOLOGY REPORT - ANNOTATIONS


Term:GTPase activity
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Accession:GO:0003924 term browser browse the term
Definition:Catalysis of the reaction: GTP + H2O = GDP + phosphate.
Synonyms:narrow_synonym: ARF small monomeric GTPase activity;   RHEB small monomeric GTPase activity;   Rab small monomeric GTPase activity;   Ran small monomeric GTPase activity;   Ras small monomeric GTPase activity;   Rho small monomeric GTPase activity;   Sar small monomeric GTPase activity;   dynamin GTPase activity;   heterotrimeric G-protein GTPase activity;   protein-synthesizing GTPase activity;   protein-synthesizing GTPase activity, elongation;   protein-synthesizing GTPase activity, initiation;   protein-synthesizing GTPase activity, termination;   signal-recognition-particle GTPase activity;   small monomeric GTPase activity;   tubulin GTPase activity
 broad_synonym: hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
 related_synonym: GTPase activity, coupled;   heterotrimeric G-protein GTPase, alpha-subunit;   heterotrimeric G-protein GTPase, beta-subunit;   heterotrimeric G-protein GTPase, gamma-subunit
 alt_id: GO:0061745
 xref: RHEA:19669;   reactome:R-HSA-1445143 "RAB8A,10,13,14 hydrolyze GTP";   reactome:R-HSA-1458485 "RALA hydrolyzes GTP";   reactome:R-HSA-156923 "Hydrolysis of eEF1A:GTP";   reactome:R-HSA-164381 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-165055 "Hydrolysis of Ran:GTP to Ran:GDP";   reactome:R-HSA-167415 "G-protein alpha subunit is inactivated";   reactome:R-HSA-170666 "Adenylate cyclase increases the GTPase activity of G alpha-olf";   reactome:R-HSA-170685 "Adenylaye cyclase increases the GTPase activity of G alpha-olf";   reactome:R-HSA-170686 "Adenylate cyclase increases the GTPase activity of Gi alpha";   reactome:R-HSA-177501 "Endocytosis (internalization) of clathrin-coated vesicle";   reactome:R-HSA-203973 "Vesicle budding";   reactome:R-HSA-2130641 "Translocation of TGN-lysosome vesicle to lysosome";   reactome:R-HSA-2130725 "Internalization of MHC II:Ii clathrin coated vesicle";   reactome:R-HSA-2584246 "GNAT1-GTP hydrolyses its bound GTP to GDP";   reactome:R-HSA-380979 "RHEB in mTORC1:RHEB:GTP hydrolyses GTP";   reactome:R-HSA-392133 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-392212 "G alpha (i) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-418574 "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-418582 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-421835 "trans-Golgi Network Vesicle Scission";   reactome:R-HSA-428941 "P2Y purinoceptor 1 activates MAP kinase p38 alpha";   reactome:R-HSA-432707 "trans-Golgi Network Lysosomal Vesicle Scission";   reactome:R-HSA-5333615 "80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC";   reactome:R-HSA-5389839 "39S subunit binds 28S subunit:mRNA:fMet-tRNA";   reactome:R-HSA-5389842 "TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome";   reactome:R-HSA-5419273 "Hydrolysis of GTP and dissociation of 28S and 39S subunits";   reactome:R-HSA-5419279 "Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA)";   reactome:R-HSA-555065 "Formation of clathrin coated vesicle";   reactome:R-HSA-5623513 "ASAP1 stimulates GTPase activity of ARF4";   reactome:R-HSA-5638006 "ARL3 hydrolyzes GTP";   reactome:R-HSA-5658231 "RAS GAPs stimulate RAS GTPase activity";   reactome:R-HSA-5665809 "SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments";   reactome:R-HSA-5672017 "Rheb in the mTORC1 complex hydrolyses GTP";   reactome:R-HSA-5694527 "Loss of SAR1B GTPase";   reactome:R-HSA-6807877 "ARFGAPs stimulate ARF GTPase activity";   reactome:R-HSA-6814833 "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP";   reactome:R-HSA-8847534 "RAB43 hydrolyses GTP";   reactome:R-HSA-8847883 "CYTH proteins stimulate ARF1 GTPase activity";   reactome:R-HSA-8849082 "ARHGAP35 stimulates RHOA GTPase activity";   reactome:R-HSA-8854173 "TBC RabGAPs accelerate GTP hydrolysis by RAB35";   reactome:R-HSA-8854255 "TBC1D2A accelerates GTP hydrolysis by RAB7";   reactome:R-HSA-8854329 "TBC1D15 accelerates GTP hydrolysis by RAB7";   reactome:R-HSA-8854604 "TBC1D16 accelerates GTP hydrolysis by RAB4A";   reactome:R-HSA-8854612 "TBC1D25 accelerates GTP hydrolysis by RAB33B";   reactome:R-HSA-8868661 "Dynamin-mediated GTP hydrolysis promotes vesicle scission";   reactome:R-HSA-8981353 "RASA1 stimulates RAS GTPase activity";   reactome:R-HSA-8982020 "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated";   reactome:R-HSA-8982021 "G alpha (z) in G alpha (z):RGS complex is inactivated";   reactome:R-HSA-8982025 "G alpha (q) in G (q):RGS complex is inactivated";   reactome:R-HSA-983422 "Disassembly of COPII coated vesicle"


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GTPase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adss1 adenylosuccinate synthase 1 JBrowse link NW_004955538 3,179,299 3,196,251 RGD:9068941
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link NW_004955458 5,436,544 5,448,201 RGD:9068941
G Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 JBrowse link NW_004955491 5,546,097 5,573,866 RGD:9068941
G Arf1 ADP ribosylation factor 1 JBrowse link NW_004955581 319,942 335,112 RGD:9068941
G Arf3 ADP ribosylation factor 3 JBrowse link NW_004955500 7,756,936 7,761,953 RGD:9068941
G Arf4 ADP ribosylation factor 4 JBrowse link NW_004955430 7,288,386 7,319,449 RGD:9068941
G Arf5 ADP ribosylation factor 5 JBrowse link NW_004955479 8,644,658 8,647,697 RGD:9068941
G Arf6 ADP ribosylation factor 6 JBrowse link NW_004955409 12,814,814 12,818,142 RGD:9068941
G Arfrp1 ADP ribosylation factor related protein 1 JBrowse link NW_004955528 519,887 529,012 RGD:9068941
G Arhgap35 Rho GTPase activating protein 35 JBrowse link NW_004955574 915,604 984,744 RGD:9068941
G Arhgap5 Rho GTPase activating protein 5 JBrowse link NW_004955409 28,627,176 28,682,302 RGD:9068941
G Arhgdib Rho GDP dissociation inhibitor beta JBrowse link NW_004955413 11,670,889 11,688,357 RGD:9068941
G Arl1 ADP ribosylation factor like GTPase 1 JBrowse link NW_004955405 36,913,011 36,932,383 RGD:9068941
G Arl2 ADP ribosylation factor like GTPase 2 JBrowse link NW_004955422 20,166,956 20,172,954 RGD:9068941
G Arl3 ADP ribosylation factor like GTPase 3 JBrowse link NW_004955485 7,739,556 7,772,582 RGD:9068941
G Arl4c ADP ribosylation factor like GTPase 4C JBrowse link NW_004955453 1,799,917 1,803,498 RGD:9068941
G Arl4d ADP ribosylation factor like GTPase 4D JBrowse link NW_004955451 16,912,424 16,913,447 RGD:9068941
G Arl6 ADP ribosylation factor like GTPase 6 JBrowse link NW_004955407 360,898 387,563 RGD:9068941
G Arl8a ADP ribosylation factor like GTPase 8A JBrowse link NW_004955406 38,223,115 38,226,563 RGD:9068941
G Arl8b ADP ribosylation factor like GTPase 8B JBrowse link NW_004955421 8,231,337 8,276,907 RGD:9068941
G Atl1 atlastin GTPase 1 JBrowse link NW_004955409 12,222,591 12,301,990 RGD:9068941
G Atl2 atlastin GTPase 2 JBrowse link NW_004955441 6,004,209 6,034,484 RGD:9068941
G Atl3 atlastin GTPase 3 JBrowse link NW_004955422 21,359,152 21,406,151 RGD:9068941
G Bms1 BMS1 ribosome biogenesis factor JBrowse link NW_004955546 1,054,208 1,089,048 RGD:9068941
G Cdc42 cell division cycle 42 JBrowse link NW_004955452 2,255,940 2,299,042 RGD:9068941
G Cplane2 ciliogenesis and planar polarity effector 2 JBrowse link NW_004955527 2,060,063 2,064,152 RGD:9068941
G Ddx3x DEAD-box helicase 3 X-linked JBrowse link NW_004955565 1,387,043 1,403,624 RGD:9068941
G Diras1 DIRAS family GTPase 1 JBrowse link NW_004955495 5,002,803 5,005,203 RGD:9068941
G Diras2 DIRAS family GTPase 2 JBrowse link NW_004955515 1,526,436 1,551,811 RGD:9068941
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 JBrowse link NW_004955469 7,046,671 7,078,666 RGD:9068941
G Dnm1 dynamin 1 JBrowse link NW_004955570 752,335 781,770 RGD:9068941
G Dnm1l dynamin 1 like JBrowse link NW_004955505 3,025,742 3,081,491 RGD:9068941
G Dnm2 dynamin 2 JBrowse link NW_004955495 1,860,644 1,934,589 RGD:9068941
G Dnm3 dynamin 3 JBrowse link NW_004955406 12,345,483 12,881,182 RGD:9068941
G Drg1 developmentally regulated GTP binding protein 1 JBrowse link NW_004955455 5,588,313 5,608,091 RGD:9068941
G Drg2 developmentally regulated GTP binding protein 2 JBrowse link NW_004955478 11,193,245 11,210,917 RGD:9068941
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 JBrowse link NW_004955493 8,661,317 8,663,190 RGD:9068941
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 JBrowse link NW_004955528 717,338 726,383 RGD:9068941
G Eef2 eukaryotic translation elongation factor 2 JBrowse link NW_004955495 4,800,103 4,807,714 RGD:9068941
G Eefsec eukaryotic elongation factor, selenocysteine-tRNA specific JBrowse link NW_004955429 15,381,257 15,598,355 RGD:9068941
G Efl1 elongation factor like GTPase 1 JBrowse link NW_004955416 12,658,177 12,789,657 RGD:9068941
G Eftud2 elongation factor Tu GTP binding domain containing 2 JBrowse link NW_004955451 17,655,659 17,690,117 RGD:9068941
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma JBrowse link NW_004955509 4,437,044 4,457,819 RGD:9068941
G Eif5b eukaryotic translation initiation factor 5B JBrowse link NW_004955470 5,622,128 5,676,533 RGD:9068941
G Eras ES cell expressed Ras JBrowse link NW_004955543 381,756 383,093 RGD:9068941
G Gbp5 guanylate binding protein 5 JBrowse link NW_004955423 4,914,430 4,926,850 RGD:9068941
G Gch1 GTP cyclohydrolase 1 JBrowse link NW_004955409 8,624,225 8,670,436 RGD:9068941
G Gem GTP binding protein overexpressed in skeletal muscle JBrowse link NW_004955417 10,475,967 10,486,879 RGD:9068941
G Gfm1 G elongation factor mitochondrial 1 JBrowse link NW_004955448 9,390,576 9,432,919 RGD:9068941
G Gfm2 GTP dependent ribosome recycling factor mitochondrial 2 JBrowse link NW_004955425 25,904,020 25,942,384 RGD:9068941
G Gna11 G protein subunit alpha 11 JBrowse link NW_004955495 5,286,891 5,302,631 RGD:9068941
G Gna12 G protein subunit alpha 12 JBrowse link NW_004955460 12,534,210 12,628,090 RGD:9068941
G Gna13 G protein subunit alpha 13 JBrowse link NW_004955478 4,510,932 4,552,646 RGD:9068941
G Gna14 G protein subunit alpha 14 JBrowse link NW_004955512 1,703,750 1,918,321 RGD:9068941
G Gna15 G protein subunit alpha 15 JBrowse link NW_004955495 5,254,546 5,270,864 RGD:9068941
G Gnai1 G protein subunit alpha i1 JBrowse link NW_004955410 5,388,184 5,467,022 RGD:9068941
G Gnai2 G protein subunit alpha i2 JBrowse link NW_004955532 2,059,038 2,079,120 RGD:9068941
G Gnai3 G protein subunit alpha i3 JBrowse link NW_004955435 12,965,006 13,005,614 RGD:9068941
G Gnal G protein subunit alpha L JBrowse link NW_004955402 1,182,515 1,249,301 RGD:9068941
G Gnao1 G protein subunit alpha o1 JBrowse link NW_004955433 14,004,813 14,170,631 RGD:9068941
G Gnaq G protein subunit alpha q JBrowse link NW_004955512 1,381,159 1,658,409 RGD:9068941
G Gnat1 G protein subunit alpha transducin 1 JBrowse link NW_004955532 2,018,850 2,023,603 RGD:9068941
G Gnat2 G protein subunit alpha transducin 2 JBrowse link NW_004955435 13,009,147 13,021,968 RGD:9068941
G Gnat3 G protein subunit alpha transducin 3 JBrowse link NW_004955410 5,145,768 5,211,594 RGD:9068941
G Gnaz G protein subunit alpha z JBrowse link NW_004955455 7,501,153 7,554,235 RGD:9068941
G Gnb1 G protein subunit beta 1 JBrowse link NW_004955486 9,165,850 9,192,306 RGD:9068941
G Gnb2 G protein subunit beta 2 JBrowse link NW_004955573 242,815 247,740 RGD:9068941
G Gnb3 G protein subunit beta 3 JBrowse link NW_004955413 4,440,693 4,447,419 RGD:9068941
G Gnb5 G protein subunit beta 5 JBrowse link NW_004955409 2,621,144 2,642,298 RGD:9068941
G Gng10 G protein subunit gamma 10 JBrowse link NW_004955419 15,650,973 15,653,122 RGD:9068941
G Gng11 G protein subunit gamma 11 JBrowse link NW_004955432 10,664,251 10,668,749 RGD:9068941
G Gng12 G protein subunit gamma 12 JBrowse link NW_004955423 23,576,515 23,644,600 RGD:9068941
G Gng13 G protein subunit gamma 13 JBrowse link NW_004955442 16,408,295 16,414,608 RGD:9068941
G Gng2 G protein subunit gamma 2 JBrowse link NW_004955409 11,075,455 11,178,993 RGD:9068941
G Gng3 G protein subunit gamma 3 JBrowse link NW_004955599 505,666 506,887 RGD:9068941
G Gng4 G protein subunit gamma 4 JBrowse link NW_004955492 4,380,198 4,432,551 RGD:9068941
G Gng5 G protein subunit gamma 5 JBrowse link NW_004955423 9,388,501 9,393,287 RGD:9068941
G Gng7 G protein subunit gamma 7 JBrowse link NW_004955495 4,889,198 4,995,288 RGD:9068941
G Gng8 G protein subunit gamma 8 JBrowse link NW_004955574 697,254 699,282 RGD:9068941
G Gngt1 G protein subunit gamma transducin 1 JBrowse link NW_004955432 10,653,508 10,657,811 RGD:9068941
G Gngt2 G protein subunit gamma transducin 2 JBrowse link NW_004955451 12,248,916 12,252,101 RGD:9068941
G Gnl1 G protein nucleolar 1 (putative) JBrowse link NW_004955583 570,573 578,423 RGD:9068941
G Gnl2 G protein nucleolar 2 JBrowse link NW_004955452 15,376,289 15,401,285 RGD:9068941
G Gpn1 GPN-loop GTPase 1 JBrowse link NW_004955469 9,580,068 9,602,575 RGD:9068941
G Gpn2 GPN-loop GTPase 2 JBrowse link NW_004955452 6,227,126 6,234,143 RGD:9068941
G Gpn3 GPN-loop GTPase 3 JBrowse link NW_004955482 7,367,000 7,383,951 RGD:9068941
G Gspt1 G1 to S phase transition 1 JBrowse link NW_004955442 6,704,272 6,740,207 RGD:9068941
G Gspt2 G1 to S phase transition 2 JBrowse link NW_004955543 2,879,974 2,882,473 RGD:9068941
G Gtpbp1 GTP binding protein 1 JBrowse link NW_004955413 24,823,113 24,849,522 RGD:9068941
G Gtpbp2 GTP binding protein 2 JBrowse link NW_004955437 9,414,128 9,425,671 RGD:9068941
G Gtpbp3 GTP binding protein 3, mitochondrial JBrowse link NW_004955524 899,475 903,168 RGD:9068941
G Gtpbp4 GTP binding protein 4 JBrowse link NW_004955492 5,594 33,558 RGD:9068941
G Gtpbp8 GTP binding protein 8 (putative) JBrowse link NW_004955427 13,219,503 13,235,198 RGD:9068941
G Guf1 GUF1 homolog, GTPase JBrowse link NW_004955443 3,363,151 3,384,319 RGD:9068941
G Hbs1l HBS1 like translational GTPase JBrowse link NW_004955439 1,684,466 1,762,314 RGD:9068941
G Hras HRas proto-oncogene, GTPase JBrowse link NW_004955476 11,508,446 11,510,333 RGD:9068941
G Ift22 intraflagellar transport 22 JBrowse link NW_004955456 15,980,412 15,987,573 RGD:9068941
G Ift27 intraflagellar transport 27 JBrowse link NW_004955413 23,295,549 23,310,824 RGD:9068941
G Irgm immunity related GTPase M JBrowse link NW_004955408 2,338,510 2,344,566 RGD:9068941
G Kras KRAS proto-oncogene, GTPase JBrowse link NW_004955413 20,298,852 20,328,756 RGD:9068941
G Lrrk2 leucine rich repeat kinase 2 JBrowse link NW_004955505 84,324 216,923 RGD:9068941
G Lsg1 large 60S subunit nuclear export GTPase 1 JBrowse link NW_004955420 14,216,430 14,244,289 RGD:9068941
G Mfn1 mitofusin 1 JBrowse link NW_004955420 8,541,547 8,596,494 RGD:9068941
G Mfn2 mitofusin 2 JBrowse link NW_004955486 1,937,873 1,962,577 RGD:9068941
G Mmaa metabolism of cobalamin associated A JBrowse link NW_004955428 1,465,118 1,489,332 RGD:9068941
G Mmut methylmalonyl-CoA mutase JBrowse link NW_004955411 8,363,142 8,397,839 RGD:9068941
G Mras muscle RAS oncogene homolog JBrowse link NW_004955501 615,303 670,404 RGD:9068941
G Mtg1 mitochondrial ribosome associated GTPase 1 JBrowse link NW_004955477 11,040,381 11,057,912 RGD:9068941
G Mtg2 mitochondrial ribosome associated GTPase 2 JBrowse link NW_004955528 1,838,051 1,849,331 RGD:9068941
G Mtif2 mitochondrial translational initiation factor 2 JBrowse link NW_004955424 27,796,213 27,823,106 RGD:9068941
G Nkiras1 NFKB inhibitor interacting Ras like 1 JBrowse link NW_004955430 15,736,060 15,766,362 RGD:9068941
G Nkiras2 NFKB inhibitor interacting Ras like 2 JBrowse link NW_004955451 16,147,598 16,151,090 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004955435 18,001,517 18,009,105 RGD:9068941
G Nudt1 nudix hydrolase 1 JBrowse link NW_004955460 9,678,270 9,689,106 RGD:9068941
G Nuggc nuclear GTPase, germinal center associated JBrowse link NW_004955403 50,507,971 50,558,881 RGD:9068941
G Opa1 OPA1 mitochondrial dynamin like GTPase JBrowse link NW_004955420 14,927,490 15,007,082 RGD:9068941
G Rab10 RAB10, member RAS oncogene family JBrowse link NW_004955469 8,057,235 8,138,983 RGD:9068941
G Rab11a RAB11A, member RAS oncogene family JBrowse link NW_004955450 9,638,761 9,656,291 RGD:9068941
G Rab11b RAB11B, member RAS oncogene family JBrowse link NW_004955563 1,008,267 1,017,315 RGD:9068941
G Rab12 RAB12, member RAS oncogene family JBrowse link NW_004955402 3,102,709 3,109,701 RGD:9068941
G Rab13 RAB13, member RAS oncogene family JBrowse link NW_004955545 590,021 594,191 RGD:9068941
G Rab14 RAB14, member RAS oncogene family JBrowse link NW_004955419 6,790,110 6,812,870 RGD:9068941
G Rab15 RAB15, member RAS oncogene family JBrowse link NW_004955466 4,958,414 4,981,464 RGD:9068941
G Rab17 RAB17, member RAS oncogene family JBrowse link NW_004955542 2,751,953 2,759,661 RGD:9068941
G Rab18 RAB18, member RAS oncogene family JBrowse link NW_004955462 1,380,158 1,411,804 RGD:9068941
G Rab19 RAB19, member RAS oncogene family JBrowse link NW_004955494 2,878,562 2,885,766 RGD:9068941
G Rab1a RAB1A, member RAS oncogene family JBrowse link NW_004955424 19,393,589 19,421,373 RGD:9068941
G Rab1b RAB1B, member RAS oncogene family JBrowse link NW_004955422 19,039,741 19,047,088 RGD:9068941
G Rab20 RAB20, member RAS oncogene family JBrowse link NW_004955404 2,087,580 2,088,545 RGD:9068941
G Rab21 RAB21, member RAS oncogene family JBrowse link NW_004955405 11,766,674 11,778,637 RGD:9068941
G Rab22a RAB22A, member RAS oncogene family JBrowse link NW_004955445 1,167,941 1,224,932 RGD:9068941
G Rab23 RAB23, member RAS oncogene family JBrowse link NW_004955502 2,947,170 2,980,634 RGD:9068941
G Rab24 RAB24, member RAS oncogene family JBrowse link NW_004955408 29,548,839 29,551,184 RGD:9068941
G Rab25 RAB25, member RAS oncogene family JBrowse link NW_004955545 2,243,237 2,250,507 RGD:9068941
G Rab26 RAB26, member RAS oncogene family JBrowse link NW_004955442 15,114,333 15,119,481 RGD:9068941
G Rab27a RAB27A, member RAS oncogene family JBrowse link NW_004955409 588,725 621,874 RGD:9068941
G Rab27b RAB27B, member RAS oncogene family JBrowse link NW_004955402 39,357,500 39,415,530 RGD:9068941
G Rab28 RAB28, member RAS oncogene family JBrowse link NW_004955480 10,220,811 10,374,021 RGD:9068941
G Rab29 RAB29, member RAS oncogene family JBrowse link NW_004955406 41,452,733 41,468,467 RGD:9068941
G Rab2a RAB2A, member RAS oncogene family JBrowse link NW_004955444 18,091,640 18,169,971 RGD:9068941
G Rab2b RAB2B, member RAS oncogene family JBrowse link NW_004955550 2,180,326 2,195,523 RGD:9068941
G Rab30 RAB30, member RAS oncogene family JBrowse link NW_004955414 9,497,276 9,582,747 RGD:9068941
G Rab31 RAB31, member RAS oncogene family JBrowse link NW_004955402 2,354,399 2,446,537 RGD:9068941
G Rab32 RAB32, member RAS oncogene family JBrowse link NW_004955436 14,171,123 14,177,255 RGD:9068941
G Rab33a RAB33A, member RAS oncogene family JBrowse link NW_004955473 4,875,230 4,891,898 RGD:9068941
G Rab33b RAB33B, member RAS oncogene family JBrowse link NW_004955428 4,192,357 4,211,740 RGD:9068941
G Rab34 RAB34, member RAS oncogene family JBrowse link NW_004955481 4,441,290 4,445,969 RGD:9068941
G Rab35 RAB35, member RAS oncogene family JBrowse link NW_004955455 11,484,557 11,502,630 RGD:9068941
G Rab36 RAB36, member RAS oncogene family JBrowse link NW_004955455 7,574,376 7,590,024 RGD:9068941
G Rab37 RAB37, member RAS oncogene family JBrowse link NW_004955553 1,580,234 1,638,290 RGD:9068941
G Rab38 RAB38, member RAS oncogene family JBrowse link NW_004955414 5,158,860 5,214,108 RGD:9068941
G Rab39a RAB39A, member RAS oncogene family JBrowse link NW_004955412 10,224,074 10,240,270 RGD:9068941
G Rab39b RAB39B, member RAS oncogene family JBrowse link NW_004955594 424,642 431,009 RGD:9068941
G Rab3a RAB3A, member RAS oncogene family JBrowse link NW_004955524 3,220,108 3,224,376 RGD:9068941
G Rab3b RAB3B, member RAS oncogene family JBrowse link NW_004955464 7,117,908 7,177,138 RGD:9068941
G Rab3c RAB3C, member RAS oncogene family JBrowse link NW_004955446 9,335,298 9,577,919 RGD:9068941
G Rab3d RAB3D, member RAS oncogene family JBrowse link NW_004955495 2,254,336 2,259,211 RGD:9068941
G Rab40b RAB40B, member RAS oncogene family JBrowse link NW_004955506 480,236 509,038 RGD:9068941
G Rab40c RAB40C, member RAS oncogene family JBrowse link NW_004955442 16,577,843 16,614,132 RGD:9068941
G Rab42 RAB42, member RAS oncogene family JBrowse link NW_004955452 7,673,187 7,676,293 RGD:9068941
G Rab43 RAB43, member RAS oncogene family JBrowse link NW_004955429 13,474,460 13,506,979 RGD:9068941
G Rab44 RAB44, member RAS oncogene family JBrowse link NW_004955437 6,223,281 6,250,068 RGD:9068941
G Rab4a RAB4A, member RAS oncogene family JBrowse link NW_004955492 8,715,252 8,743,432 RGD:9068941
G Rab4b RAB4B, member RAS oncogene family JBrowse link NW_004955578 559,029 568,966 RGD:9068941
G Rab5a RAB5A, member RAS oncogene family JBrowse link NW_004955430 11,991,548 12,040,003 RGD:9068941
G Rab5b RAB5B, member RAS oncogene family JBrowse link NW_004955458 3,563,363 3,582,620 RGD:9068941
G Rab5c RAB5C, member RAS oncogene family JBrowse link NW_004955451 16,200,442 16,215,583 RGD:9068941
G Rab6a RAB6A, member RAS oncogene family JBrowse link NW_004955414 17,758,071 17,806,727 RGD:9068941
G Rab6b RAB6B, member RAS oncogene family JBrowse link NW_004955501 4,751,647 4,781,094 RGD:9068941
G Rab7a RAB7A, member RAS oncogene family JBrowse link NW_004955429 15,103,792 15,167,498 RGD:9068941
G Rab7b RAB7B, member RAS oncogene family JBrowse link NW_004955406 41,615,302 41,638,157 RGD:9068941
G Rab8a RAB8A, member RAS oncogene family JBrowse link NW_004955524 1,403,811 1,416,005 RGD:9068941
G Rab8b RAB8B, member RAS oncogene family JBrowse link NW_004955450 12,026,784 12,095,332 RGD:9068941
G Rab9a RAB9A, member RAS oncogene family JBrowse link NW_004955519 4,489,159 4,496,089 RGD:9068941
G Rab9b RAB9B, member RAS oncogene family JBrowse link NW_004955548 825,208 829,815 RGD:9068941
G Rabl2b RAB, member of RAS oncogene family like 2B JBrowse link NW_004955413 33,738,999 33,756,374 RGD:9068941
G Rabl3 RAB, member of RAS oncogene family like 3 JBrowse link NW_004955427 20,204,901 20,242,242 RGD:9068941
G Rac1 Rac family small GTPase 1 JBrowse link NW_004955460 13,270,159 13,295,562 RGD:9068941
G Rac2 Rac family small GTPase 2 JBrowse link NW_004955413 23,697,504 23,710,668 RGD:9068941
G Rac3 Rac family small GTPase 3 JBrowse link NW_004955506 1,139,098 1,142,443 RGD:9068941
G Rala RAS like proto-oncogene A JBrowse link NW_004955460 3,789,136 3,853,315 RGD:9068941
G Ralb RAS like proto-oncogene B JBrowse link NW_004955459 9,533,081 9,574,464 RGD:9068941
G Ran RAN, member RAS oncogene family JBrowse link NW_004955482 1,222,944 1,223,891 RGD:9068941
G Rap1a RAP1A, member of RAS oncogene family JBrowse link NW_004955435 15,090,521 15,171,397 RGD:9068941
G Rap1b RAP1B, member of RAS oncogene family JBrowse link NW_004955458 15,110,709 15,121,868 RGD:9068941
G Rap1gap RAP1 GTPase activating protein JBrowse link NW_004955452 1,886,557 1,950,942 RGD:9068941
G Rap2a RAP2A, member of RAS oncogene family JBrowse link NW_004955404 12,897,518 12,936,964 RGD:9068941
G Rap2b RAP2B, member of RAS oncogene family JBrowse link NW_004955448 4,668,477 4,671,629 RGD:9068941
G Rap2c RAP2C, member of RAS oncogene family JBrowse link NW_004955473 2,709,407 2,723,453 RGD:9068941
G Rasa1 RAS p21 protein activator 1 JBrowse link NW_004955418 23,807,740 23,897,699 RGD:9068941
G Rasd1 ras related dexamethasone induced 1 JBrowse link NW_004955577 452,993 454,659 RGD:9068941
G Rasd2 RASD family member 2 JBrowse link NW_004955405 43,191,530 43,196,057 RGD:9068941
G Rasef RAS and EF-hand domain containing JBrowse link NW_004955530 690,748 747,415 RGD:9068941
G Rasl10a RAS like family 10 member A JBrowse link NW_004955455 3,618,656 3,621,299 RGD:9068941
G Rasl10b RAS like family 10 member B JBrowse link NW_004955481 10,183,635 10,192,155 RGD:9068941
G Rasl11a RAS like family 11 member A JBrowse link NW_004955497 6,695,354 6,697,425 RGD:9068941
G Rasl11b RAS like family 11 member B JBrowse link NW_004955447 17,755,277 17,758,827 RGD:9068941
G Rasl12 RAS like family 12 JBrowse link NW_004955450 10,352,574 10,363,906 RGD:9068941
G Rem1 RRAD and GEM like GTPase 1 JBrowse link NW_004955422 29,434,477 29,443,172 RGD:9068941
G Rem2 RRAD and GEM like GTPase 2 JBrowse link NW_004955409 37,403,758 37,408,312 RGD:9068941
G Rerg RAS like estrogen regulated growth inhibitor JBrowse link NW_004955413 11,825,235 11,940,390 RGD:9068941
G Rergl RERG like JBrowse link NW_004955413 14,324,734 14,334,992 RGD:9068941
G Rgs1 regulator of G protein signaling 1 JBrowse link NW_004955406 30,042,354 30,047,172 RGD:9068941
G Rgs10 regulator of G protein signaling 10 JBrowse link NW_004955551 318,229 348,578 RGD:9068941
G Rgs11 regulator of G protein signaling 11 JBrowse link NW_004955442 16,905,982 16,914,772 RGD:9068941
G Rgs12 regulator of G protein signaling 12 JBrowse link NW_004955514 2,081,575 2,154,414 RGD:9068941
G Rgs13 regulator of G protein signaling 13 JBrowse link NW_004955406 30,111,770 30,134,605 RGD:9068941
G Rgs14 regulator of G protein signaling 14 JBrowse link NW_004955408 29,602,654 29,616,793 RGD:9068941
G Rgs16 regulator of G protein signaling 16 JBrowse link NW_004955406 21,439,536 21,444,822 RGD:9068941
G Rgs17 regulator of G protein signaling 17 JBrowse link NW_004955439 8,687,775 8,805,229 RGD:9068941
G Rgs18 regulator of G protein signaling 18 JBrowse link NW_004955406 29,573,127 29,594,991 RGD:9068941
G Rgs19 regulator of G protein signaling 19 JBrowse link NW_004955528 183,067 185,703 RGD:9068941
G Rgs2 regulator of G protein signaling 2 JBrowse link NW_004955406 30,261,757 30,265,389 RGD:9068941
G Rgs20 regulator of G protein signaling 20 JBrowse link NW_004955454 13,271,409 13,305,730 RGD:9068941
G Rgs21 regulator of G protein signaling 21 JBrowse link NW_004955406 29,778,745 29,800,009 RGD:9068941
G Rgs3 regulator of G protein signaling 3 JBrowse link NW_004955419 13,918,274 14,042,090 RGD:9068941
G Rgs4 regulator of G protein signaling 4 JBrowse link NW_004955462 13,340,812 13,347,598 RGD:9068941
G Rgs5 regulator of G protein signaling 5 JBrowse link NW_004955462 13,228,110 13,288,063 RGD:9068941
G Rgs6 regulator of G protein signaling 6 JBrowse link NW_004955523 2,763,143 3,366,851 RGD:9068941
G Rgs7 regulator of G protein signaling 7 JBrowse link NW_004955406 10,669,127 11,127,564 RGD:9068941
G Rgs8 regulator of G protein signaling 8 JBrowse link NW_004955406 21,482,810 21,523,518 RGD:9068941
G Rgs9 regulator of G protein signaling 9 JBrowse link NW_004955478 4,614,730 4,683,152 RGD:9068941
G Rheb Ras homolog, mTORC1 binding JBrowse link NW_004955491 5,795,040 5,833,897 RGD:9068941
G Rhebl1 RHEB like 1 JBrowse link NW_004955500 7,894,686 7,898,035 RGD:9068941
G Rhoa ras homolog family member A JBrowse link NW_004955532 1,300,821 1,347,453 RGD:9068941
G Rhob ras homolog family member B JBrowse link NW_004955469 2,964,968 2,966,998 RGD:9068941
G Rhobtb1 Rho related BTB domain containing 1 JBrowse link NW_004955425 14,299,128 14,366,732 RGD:9068941
G Rhobtb2 Rho related BTB domain containing 2 JBrowse link NW_004955403 46,367,390 46,390,551 RGD:9068941
G Rhobtb3 Rho related BTB domain containing 3 JBrowse link NW_004955418 16,772,363 16,839,347 RGD:9068941
G Rhoc ras homolog family member C JBrowse link NW_004955435 16,115,095 16,117,736 RGD:9068941
G Rhod ras homolog family member D JBrowse link NW_004955422 18,343,611 18,353,269 RGD:9068941
G Rhof ras homolog family member F, filopodia associated JBrowse link NW_004955482 6,631,327 6,643,634 RGD:9068941
G Rhog ras homolog family member G JBrowse link NW_004955414 19,630,564 19,641,722 RGD:9068941
G Rhoh ras homolog family member H JBrowse link NW_004955443 7,227,751 7,269,984 RGD:9068941
G Rhoj ras homolog family member J JBrowse link NW_004955466 6,476,822 6,564,890 RGD:9068941
G Rhoq ras homolog family member Q JBrowse link NW_004955441 13,457,757 13,495,221 RGD:9068941
G Rhot1 ras homolog family member T1 JBrowse link NW_004955481 7,149,836 7,199,296 RGD:9068941
G Rhot2 ras homolog family member T2 JBrowse link NW_004955442 16,528,886 16,534,856 RGD:9068941
G Rhou ras homolog family member U JBrowse link NW_004955492 8,949,003 8,955,502 RGD:9068941
G Rhov ras homolog family member V JBrowse link NW_004955416 7,741,762 7,743,816 RGD:9068941
G Rit1 Ras like without CAAX 1 JBrowse link NW_004955545 2,089,530 2,099,404 RGD:9068941
G Rit2 Ras like without CAAX 2 JBrowse link NW_004955402 28,737,882 29,137,006 RGD:9068941
G Rnd1 Rho family GTPase 1 JBrowse link NW_004955500 7,703,461 7,709,363 RGD:9068941
G Rnd2 Rho family GTPase 2 JBrowse link NW_004955451 16,806,527 16,809,091 RGD:9068941
G Rnd3 Rho family GTPase 3 JBrowse link NW_004955440 16,106,555 16,113,337 RGD:9068941
G Rnf112 ring finger protein 112 JBrowse link NW_004955467 349,703 355,922 RGD:9068941
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link NW_004955433 23,426,258 23,439,094 RGD:9068941
G Rraga Ras related GTP binding A JBrowse link NW_004955434 21,509,528 21,510,885 RGD:9068941
G Rragb Ras related GTP binding B JBrowse link NW_004955475 2,662,969 2,692,253 RGD:9068941
G Rragc Ras related GTP binding C JBrowse link NW_004955452 16,469,426 16,486,336 RGD:9068941
G Rragd Ras related GTP binding D JBrowse link NW_004955411 16,111,931 16,155,662 RGD:9068941
G Rras RAS related JBrowse link NW_004955559 1,244,658 1,248,774 RGD:9068941
G Rras2 RAS related 2 JBrowse link NW_004955414 29,482,502 29,546,102 RGD:9068941
G Sar1a secretion associated Ras related GTPase 1A JBrowse link NW_004955437 21,075,632 21,093,608 RGD:9068941
G Sar1b secretion associated Ras related GTPase 1B JBrowse link NW_004955408 5,737,197 5,761,228 RGD:9068941
G Septin1 septin 1 JBrowse link NW_004955493 7,304,472 7,309,022 RGD:9068941
G Septin10 septin 10 JBrowse link NW_004955470 12,647,145 12,697,616 RGD:9068941
G Septin11 septin 11 JBrowse link NW_004955433 1,606,246 1,691,819 RGD:9068941
G Septin12 septin 12 JBrowse link NW_004955442 12,704,546 12,717,905 RGD:9068941
G Septin14 septin 14 JBrowse link NW_004955456 8,066,570 8,102,318 RGD:9068941
G Septin2 septin 2 JBrowse link NW_004955542 401,081 444,304 RGD:9068941
G Septin3 septin 3 JBrowse link NW_004955413 27,381,103 27,400,899 RGD:9068941
G Septin4 septin 4 JBrowse link NW_004955451 4,505,318 4,530,387 RGD:9068941
G Septin5 septin 5 JBrowse link NW_004955442 18,361,072 18,369,648 RGD:9068941
G Septin6 septin 6 JBrowse link NW_004955534 306,691 381,799 RGD:9068941
G Septin7 septin 7 JBrowse link NW_004955460 7,287,452 7,374,747 RGD:9068941
G Septin8 septin 8 JBrowse link NW_004955408 4,129,302 4,143,683 RGD:9068941
G Septin9 septin 9 JBrowse link NW_004955506 4,943,108 5,033,088 RGD:9068941
G Srp54 signal recognition particle 54 JBrowse link NW_004955409 25,977,226 26,016,351 RGD:9068941
G Srpra SRP receptor subunit alpha JBrowse link NW_004955412 27,287,359 27,293,362 RGD:9068941
G Tbcc tubulin folding cofactor C JBrowse link NW_004955437 8,808,021 8,809,598 RGD:9068941
G Tmem250 transmembrane protein 250 JBrowse link NW_004955513 4,520,445 4,524,203 RGD:9068941
G Trim23 tripartite motif containing 23 JBrowse link NW_004955446 3,480,177 3,509,050 RGD:9068941
G Tsr1 TSR1 ribosome maturation factor JBrowse link NW_004955481 907,441 919,613 RGD:9068941
G Tuba4a tubulin alpha 4a JBrowse link NW_004955453 14,177,043 14,180,814 RGD:9068941
G Tuba8 tubulin alpha 8 JBrowse link NW_004955454 6,129,821 6,148,645 RGD:9068941
G Tubb tubulin beta class I JBrowse link NW_004955583 704,811 715,742 RGD:9068941
G Tubb1 tubulin beta 1 class VI JBrowse link NW_004955445 569,504 576,129 RGD:9068941
G Tubb4a tubulin beta 4A class IVa JBrowse link NW_004955495 3,134,181 3,138,725 RGD:9068941
G Tubb4b tubulin beta 4B class IVb JBrowse link NW_004955513 5,237,050 5,239,370 RGD:9068941
G Tubb6 tubulin beta 6 class V JBrowse link NW_004955402 1,071,135 1,081,385 RGD:9068941
G Tubd1 tubulin delta 1 JBrowse link NW_004955451 3,225,728 3,249,013 RGD:9068941
G Tube1 tubulin epsilon 1 JBrowse link NW_004955526 4,484,867 4,519,603 RGD:9068941
G Tufm Tu translation elongation factor, mitochondrial JBrowse link NW_004955493 6,619,205 6,623,780 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14671
    catalytic activity 5183
      hydrolase activity 2250
        hydrolase activity, acting on acid anhydrides 794
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 794
            pyrophosphatase activity 791
              nucleoside-triphosphatase activity 738
                GTPase activity 284
                  GTPase motor activity + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.