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ONTOLOGY REPORT - ANNOTATIONS


Term:GTPase activity
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Accession:GO:0003924 term browser browse the term
Definition:Catalysis of the reaction: GTP + H2O = GDP + phosphate.
Synonyms:narrow_synonym: ARF small monomeric GTPase activity;   RHEB small monomeric GTPase activity;   Rab small monomeric GTPase activity;   Ran small monomeric GTPase activity;   Ras small monomeric GTPase activity;   Rho small monomeric GTPase activity;   Sar small monomeric GTPase activity;   dynamin GTPase activity;   heterotrimeric G-protein GTPase activity;   protein-synthesizing GTPase activity;   protein-synthesizing GTPase activity, elongation;   protein-synthesizing GTPase activity, initiation;   protein-synthesizing GTPase activity, termination;   signal-recognition-particle GTPase activity;   small monomeric GTPase activity;   tubulin GTPase activity
 broad_synonym: hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
 related_synonym: heterotrimeric G-protein GTPase, alpha-subunit;   heterotrimeric G-protein GTPase, beta-subunit;   heterotrimeric G-protein GTPase, gamma-subunit
 xref: RHEA:19669;   reactome:R-HSA-1445143 "RAB8A,10,13,14 hydrolyze GTP";   reactome:R-HSA-1458485 "RALA hydrolyzes GTP";   reactome:R-HSA-156923 "Hydrolysis of eEF1A:GTP";   reactome:R-HSA-164381 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-165055 "Hydrolysis of Ran:GTP to Ran:GDP";   reactome:R-HSA-167415 "G-protein alpha subunit is inactivated";   reactome:R-HSA-170666 "Adenylate cyclase increases the GTPase activity of G alpha-olf";   reactome:R-HSA-170685 "Adenylaye cyclase increases the GTPase activity of G alpha-olf";   reactome:R-HSA-170686 "Adenylate cyclase increases the GTPase activity of Gi alpha";   reactome:R-HSA-177501 "Endocytosis (internalization) of clathrin-coated vesicle";   reactome:R-HSA-203973 "Vesicle budding";   reactome:R-HSA-2130641 "Translocation of TGN-lysosome vesicle to lysosome";   reactome:R-HSA-2130725 "Internalization of MHC II:Ii clathrin coated vesicle";   reactome:R-HSA-2584246 "GNAT1-GTP hydrolyses its bound GTP to GDP";   reactome:R-HSA-380979 "RHEB in mTORC1:RHEB:GTP hydrolyses GTP";   reactome:R-HSA-392133 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-392212 "G alpha (i) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-418574 "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-418582 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-421835 "trans-Golgi Network Vesicle Scission";   reactome:R-HSA-428941 "P2Y purinoceptor 1 activates MAP kinase p38 alpha";   reactome:R-HSA-432707 "trans-Golgi Network Lysosomal Vesicle Scission";   reactome:R-HSA-5333615 "80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC";   reactome:R-HSA-5389839 "39S subunit binds 28S subunit:mRNA:fMet-tRNA";   reactome:R-HSA-5389842 "TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome";   reactome:R-HSA-5419273 "Hydrolysis of GTP and dissociation of 28S and 39S subunits";   reactome:R-HSA-5419279 "Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA)";   reactome:R-HSA-555065 "Formation of clathrin coated vesicle";   reactome:R-HSA-5623513 "ASAP1 stimulates GTPase activity of ARF4";   reactome:R-HSA-5638006 "ARL3 hydrolyzes GTP";   reactome:R-HSA-5658231 "RAS GAPs stimulate RAS GTPase activity";   reactome:R-HSA-5665809 "SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments";   reactome:R-HSA-5672017 "Rheb in the mTORC1 complex hydrolyses GTP";   reactome:R-HSA-5694527 "Loss of SAR1B GTPase";   reactome:R-HSA-6807877 "ARFGAPs stimulate ARF GTPase activity";   reactome:R-HSA-6814833 "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP";   reactome:R-HSA-8847534 "RAB43 hydrolyses GTP";   reactome:R-HSA-8847883 "CYTH proteins stimulate ARF1 GTPase activity";   reactome:R-HSA-8849082 "ARHGAP35 stimulates RHOA GTPase activity";   reactome:R-HSA-8854173 "TBC RabGAPs accelerate GTP hydrolysis by RAB35";   reactome:R-HSA-8854255 "TBC1D2A accelerates GTP hydrolysis by RAB7";   reactome:R-HSA-8854329 "TBC1D15 accelerates GTP hydrolysis by RAB7";   reactome:R-HSA-8854604 "TBC1D16 accelerates GTP hydrolysis by RAB4A";   reactome:R-HSA-8854612 "TBC1D25 accelerates GTP hydrolysis by RAB33B";   reactome:R-HSA-8868661 "Dynamin-mediated GTP hydrolysis promotes vesicle scission";   reactome:R-HSA-8981353 "RASA1 stimulates RAS GTPase activity";   reactome:R-HSA-8982020 "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated";   reactome:R-HSA-8982021 "G alpha (z) in G alpha (z):RGS complex is inactivated";   reactome:R-HSA-8982025 "G alpha (q) in G (q):RGS complex is inactivated";   reactome:R-HSA-983422 "Disassembly of COPII coated vesicle"


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GTPase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 JBrowse link 15 135,442,440 135,999,162 RGD:14298760
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 5 23,015,777 23,035,943 RGD:14298760
G AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 JBrowse link 18 6,081,680 6,145,115 RGD:14298760
G ARF6 ADP ribosylation factor 6 JBrowse link 1 179,697,582 179,717,299 RGD:14298760
G ARHGAP35 Rho GTPase activating protein 35 JBrowse link 6 52,711,463 52,841,295 RGD:14298760
G ARHGDIB Rho GDP dissociation inhibitor beta JBrowse link 5 57,576,754 57,598,395 RGD:14298760
G ARL1 ADP ribosylation factor like GTPase 1 JBrowse link 5 82,795,741 82,812,153 RGD:14298760
G ARL2 ADP ribosylation factor like GTPase 2 JBrowse link 2 7,157,963 7,167,024 RGD:14298760
G ARL6 ADP ribosylation factor like GTPase 6 JBrowse link 13 162,509,451 162,556,675 RGD:14298760
G ATL1 atlastin GTPase 1 JBrowse link 1 180,299,434 180,407,003 RGD:14298760
G ATL2 atlastin GTPase 2 JBrowse link 3 101,957,189 102,029,120 RGD:14298760
G ATL3 atlastin GTPase 3 JBrowse link 2 8,361,579 8,408,920 RGD:14298760
G BMS1 BMS1 ribosome biogenesis factor JBrowse link 14 61,056,075 61,125,984 RGD:14298760
G CDC42 cell division cycle 42 JBrowse link 6 80,035,034 80,089,243 RGD:14298760
G CPLANE2 ciliogenesis and planar polarity effector 2 JBrowse link 6 75,345,153 75,350,544 RGD:14298760
G CRACR2A calcium release activated channel regulator 2A JBrowse link 5 66,574,758 66,650,447 RGD:14298760
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 36,988,031 37,005,496 RGD:14298760
G DIRAS1 DIRAS family GTPase 1 JBrowse link 2 75,921,145 75,927,231 RGD:14298760
G DIRAS2 DIRAS family GTPase 2 JBrowse link 14 1,964,842 1,987,900 RGD:14298760
G DIRAS3 DIRAS family GTPase 3 JBrowse link 6 144,576,342 144,578,820 RGD:14298760
G DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 JBrowse link 3 113,816,718 113,857,117 RGD:14298760
G DNM1 dynamin 1 JBrowse link 1 268,653,045 268,702,233 RGD:14298760
G DNM1L dynamin 1 like JBrowse link 5 41,571,054 41,636,058 RGD:14298760
G DNM2 dynamin 2 JBrowse link 2 69,474,011 69,574,427 RGD:14298760
G DNM3 dynamin 3 JBrowse link 9 114,262,782 114,805,252 RGD:14298760
G DRG1 developmentally regulated GTP binding protein 1 JBrowse link 14 48,126,807 48,153,103 RGD:14298760
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 JBrowse link 1 92,421,235 92,425,053 RGD:14298760
G EEF1A2 eukaryotic translation elongation factor 1 alpha 2 JBrowse link 17 62,517,811 62,526,379 RGD:14298760
G EEF2 eukaryotic translation elongation factor 2 JBrowse link 2 74,746,541 74,756,687 RGD:14298760
G EEFSEC eukaryotic elongation factor, selenocysteine-tRNA specific JBrowse link 13 72,041,409 72,196,345 RGD:14298760
G EFL1 elongation factor like GTPase 1 JBrowse link 7 50,839,725 50,977,024 RGD:14298760
G EFTUD2 elongation factor Tu GTP binding domain containing 2 JBrowse link 12 18,474,367 18,514,993 RGD:14298760
G EIF2S3 eukaryotic translation initiation factor 2 subunit gamma JBrowse link X 20,129,708 20,162,881 RGD:14298760
G EIF5B eukaryotic translation initiation factor 5B JBrowse link 3 54,861,759 54,930,826 RGD:14298760
G GBP1 guanylate binding protein 1, interferon-inducible JBrowse link 4 127,425,699 127,442,132 RGD:14298760
G GBP2 guanylate binding protein 2, interferon-inducible JBrowse link 4 127,387,222 127,408,729 RGD:14298760
G GCH1 GTP cyclohydrolase 1 JBrowse link 1 184,201,232 184,264,060 RGD:14298760
G GEM GTP binding protein overexpressed in skeletal muscle JBrowse link 4 42,458,591 42,471,941 RGD:14298760
G GFM1 G elongation factor mitochondrial 1 JBrowse link 13 98,411,132 98,456,496 RGD:14298760
G GFM2 GTP dependent ribosome recycling factor mitochondrial 2 JBrowse link 2 83,770,518 83,843,896 RGD:14298760
G GNA11 G protein subunit alpha 11 JBrowse link 2 75,439,405 75,456,855 RGD:14298760
G GNA12 G protein subunit alpha 12 JBrowse link 3 2,002,494 2,105,937 RGD:14298760
G GNA13 G protein subunit alpha 13 JBrowse link 12 11,922,630 11,966,913 RGD:14298760
G GNA14 G protein subunit alpha 14 JBrowse link 1 230,341,947 230,545,123 RGD:14298760
G GNA15 G protein subunit alpha 15 JBrowse link 2 75,408,723 75,433,809 RGD:14298760
G GNAI1 G protein subunit alpha i1 JBrowse link 9 100,187,878 100,272,274 RGD:14298760
G GNAI2 G protein subunit alpha i2 JBrowse link 13 32,705,326 32,733,804 RGD:14298760
G GNAI3 G protein subunit alpha i3 JBrowse link 4 110,527,363 110,579,331 RGD:14298760
G GNAL G protein subunit alpha L JBrowse link 6 97,342,468 97,429,334 RGD:14298760
G GNAO1 G protein subunit alpha o1 JBrowse link 6 29,416,574 29,592,874 RGD:14298760
G GNAQ G protein subunit alpha q JBrowse link 1 230,607,469 230,906,988 RGD:14298760
G GNAS GNAS complex locus JBrowse link 17 58,985,580 59,053,022 RGD:14298760
G GNAT1 G protein subunit alpha transducin 1 JBrowse link 13 32,671,377 32,678,394 RGD:14298760
G GNAT2 G protein subunit alpha transducin 2 JBrowse link 4 110,512,349 110,523,222 RGD:14298760
G GNAT3 G protein subunit alpha transducin 3 JBrowse link 9 99,848,406 99,910,236 RGD:14298760
G GNAZ G protein subunit alpha z JBrowse link 14 49,132,012 49,174,114 RGD:14298760
G GNB1 G protein subunit beta 1 JBrowse link 6 63,867,155 63,957,514 RGD:14298760
G GNG13 G protein subunit gamma 13 JBrowse link 3 40,997,556 41,000,718 RGD:14298760
G GNG14 G protein subunit gamma 14 JBrowse link 2 66,297,770 66,303,125 RGD:14298760
G GNG2 G protein subunit gamma 2 JBrowse link 1 181,485,257 181,651,972 RGD:14298760
G GNG8 G protein subunit gamma 8 JBrowse link 6 52,534,952 52,541,115 RGD:14298760
G GNGT1 G protein subunit gamma transducin 1 JBrowse link 9 73,403,647 73,717,746 RGD:14298760
G GPATCH3 G-patch domain containing 3 JBrowse link 6 84,200,727 84,218,710 RGD:14298760
G GPN1 GPN-loop GTPase 1 JBrowse link 3 111,541,010 111,565,065 RGD:14298760
G GPN2 GPN-loop GTPase 2 JBrowse link 6 84,200,152 84,209,729 RGD:14298760
G GPN3 GPN-loop GTPase 3 JBrowse link 14 31,836,733 31,849,559 RGD:14298760
G GSPT1 G1 to S phase transition 1 JBrowse link 3 31,237,155 31,273,832 RGD:14298760
G GSPT2 G1 to S phase transition 2 JBrowse link X 45,193,336 45,195,939 RGD:14298760
G GTPBP1 GTP binding protein 1 JBrowse link 5 9,294,329 9,322,192 RGD:14298760
G GTPBP2 GTP binding protein 2 JBrowse link 7 38,598,763 38,613,217 RGD:14298760
G GTPBP3 GTP binding protein 3, mitochondrial JBrowse link 2 60,352,012 60,355,403 RGD:14298760
G GTPBP4 GTP binding protein 4 JBrowse link 10 68,547,316 68,566,040 RGD:14298760
G GUF1 GUF1 homolog, GTPase JBrowse link 8 35,167,615 35,190,587 RGD:14298760
G HBS1L HBS1 like translational GTPase JBrowse link 1 28,968,778 29,052,427 RGD:14298760
G HRAS HRas proto-oncogene, GTPase JBrowse link 2 299,662 302,539 RGD:14298760
G IFT27 intraflagellar transport 27 JBrowse link 5 10,994,182 11,015,476 RGD:14298760
G KLC2 kinesin light chain 2 JBrowse link 2 6,117,236 6,127,048 RGD:14298760
G KRAS KRAS proto-oncogene, GTPase JBrowse link 5 48,508,774 48,546,260 RGD:14298760
G LOC100127131 tubulin alpha-1C chain JBrowse link 5 15,153,516 15,269,783 RGD:14298760
G LOC100155138 tubulin alpha-3 chain JBrowse link 14 50,646,616 50,657,344 RGD:14298760
G LOC100158003 tubulin alpha-1D chain JBrowse link 15 121,305,563 121,311,919 RGD:14298760
G LOC100510930 tubulin alpha-3 chain JBrowse link 14 50,594,115 50,600,789 RGD:14298760
G LOC100514912 elongation factor 1-alpha, oocyte form-like JBrowse link 9 25,500,470 25,503,084 RGD:14298760
G LOC100523310 guanylate-binding protein 6 JBrowse link 4 127,177,337 127,201,984 RGD:14298760
G LOC100523624 methylmalonic aciduria type A protein, mitochondrial JBrowse link 8 82,765,074 82,864,829 RGD:14298760
G LOC100523668 guanylate-binding protein 2-like JBrowse link 4 127,290,026 127,345,677 RGD:14298760
G LOC100620900 elongation factor 1-alpha, somatic form-like JBrowse link 6 81,508,564 81,519,275 RGD:14298760
G LOC100624149 eukaryotic translation initiation factor 2 subunit 3 JBrowse link Y 9,827,511 9,847,793 RGD:14298760
G LOC100624785 tubulin beta-2A chain JBrowse link 7 1,910,585 1,914,668 RGD:14298760
G LOC102158400 ras-related protein Rab-18-like JBrowse link 10 44,989,627 45,016,987 RGD:14298760
G LOC102161784 guanylate-binding protein 6-like JBrowse link 4 127,222,665 127,261,718 RGD:14298760
G LOC110255211 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 JBrowse link 12 25,334,619 25,340,775 RGD:14298760
G LOC110260809 rab-like protein 2A JBrowse link 5 104,510,606 104,525,994 RGD:14298760
G LRRK2 leucine rich repeat kinase 2 JBrowse link 5 71,800,337 71,945,828 RGD:14298760
G LSG1 large 60S subunit nuclear export GTPase 1 JBrowse link 13 131,623,530 131,653,930 RGD:14298760
G MFN1 mitofusin 1 JBrowse link 13 117,404,637 117,441,750 RGD:14298760
G MFN2 mitofusin 2 JBrowse link 6 72,026,512 72,056,439 RGD:14298760
G MLF1 myeloid leukemia factor 1 JBrowse link 13 98,357,804 98,405,801 RGD:14298760
G MMUT methylmalonyl-CoA mutase JBrowse link 7 43,597,313 43,624,603 RGD:14298760
G MRAS muscle RAS oncogene homolog JBrowse link 13 79,137,489 79,211,139 RGD:14298760
G MTG1 mitochondrial ribosome associated GTPase 1 JBrowse link 14 141,372,244 141,384,314 RGD:14298760
G MTG2 mitochondrial ribosome associated GTPase 2 JBrowse link 17 61,598,216 61,614,699 RGD:14298760
G MTIF2 mitochondrial translational initiation factor 2 JBrowse link 3 85,947,617 85,989,455 RGD:14298760
G MX1 MX dynamin like GTPase 1 JBrowse link 13 204,843,049 204,868,927 RGD:14298760
G MX2 myxovirus (influenza virus) resistance 2 (mouse) JBrowse link 13 204,798,633 204,821,612 RGD:14298760
G MYCBP MYC binding protein JBrowse link 6 94,805,649 94,814,443 RGD:14298760
G NKIRAS1 NFKB inhibitor interacting Ras like 1 JBrowse link 13 10,686,480 10,716,162 RGD:14298760
G NKIRAS2 NFKB inhibitor interacting Ras like 2 JBrowse link 12 20,717,545 20,723,141 RGD:14298760
G NRAS NRAS proto-oncogene, GTPase JBrowse link 4 105,845,913 105,853,769 RGD:14298760
G NUGGC nuclear GTPase, germinal center associated JBrowse link 14 11,775,684 11,826,162 RGD:14298760
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 13 130,624,771 130,718,345 RGD:14298760
G PEX26 peroxisomal biogenesis factor 26 JBrowse link 5 70,133,024 70,142,515 RGD:14298760
G RAB10 RAB10, member RAS oncogene family JBrowse link 3 112,842,190 112,924,188 RGD:14298760
G RAB11A RAB11A, member RAS oncogene family JBrowse link 1 163,858,254 163,887,741 RGD:14298760
G RAB11B RAB11B, member RAS oncogene family JBrowse link 2 70,884,457 70,896,169 RGD:14298760
G RAB12 RAB12, member RAS oncogene family JBrowse link 6 99,216,225 99,244,627 RGD:14298760
G RAB13 RAB13, member RAS oncogene family JBrowse link 4 95,705,093 95,709,942 RGD:14298760
G RAB14 RAB14, member RAS oncogene family JBrowse link 1 261,228,112 261,256,913 RGD:14298760
G RAB17 RAB17, member RAS oncogene family JBrowse link 15 137,232,781 137,255,884 RGD:14298760
G RAB18 RAB18, member RAS oncogene family JBrowse link 10 38,970,381 39,004,975 RGD:14298760
G RAB19 RAB19, member RAS oncogene family JBrowse link 18 9,367,239 9,391,097 RGD:14298760
G RAB1A RAB1A, member RAS oncogene family JBrowse link 3 76,837,673 76,868,156 RGD:14298760
G RAB1B RAB1B, member RAS oncogene family JBrowse link 2 6,110,438 6,116,443 RGD:14298760
G RAB20 RAB20, member RAS oncogene family JBrowse link 11 77,167,052 77,188,893 RGD:14298760
G RAB21 RAB21, member RAS oncogene family JBrowse link 5 35,757,273 35,788,754 RGD:14298760
G RAB22A RAB22A, member RAS oncogene family JBrowse link 17 58,514,985 58,572,421 RGD:14298760
G RAB23 RAB23, member RAS oncogene family JBrowse link 7 28,632,065 28,658,958 RGD:14298760
G RAB24 RAB24, member RAS oncogene family JBrowse link 2 80,646,426 80,651,498 RGD:14298760
G RAB25 RAB25, member RAS oncogene family JBrowse link 4 93,961,136 93,970,742 RGD:14298760
G RAB26 RAB26, member RAS oncogene family JBrowse link 3 39,831,981 39,837,510 RGD:14298760
G RAB27A RAB27A, member RAS oncogene family JBrowse link 1 116,532,816 116,606,477 RGD:14298760
G RAB27B RAB27B, member RAS oncogene family JBrowse link 1 104,241,500 104,418,721 RGD:14298760
G RAB28 RAB28, member RAS oncogene family JBrowse link 8 8,870,795 9,125,253 RGD:14298760
G RAB29 RAB29, member RAS oncogene family JBrowse link 9 66,448,854 66,458,766 RGD:14298760
G RAB2A RAB2A, member RAS oncogene family JBrowse link 4 72,800,617 72,882,183 RGD:14298760
G RAB2B RAB2B, member RAS oncogene family JBrowse link 7 77,698,907 77,717,211 RGD:14298760
G RAB30 RAB30, member RAS oncogene family JBrowse link 9 17,124,181 17,222,741 RGD:14298760
G RAB31 RAB31, member RAS oncogene family JBrowse link 6 98,278,644 98,385,857 RGD:14298760
G RAB32 RAB32, member RAS oncogene family JBrowse link 1 19,076,301 19,097,647 RGD:14298760
G RAB33A RAB33A, member RAS oncogene family JBrowse link X 106,708,402 106,723,803 RGD:14298760
G RAB33B RAB33B, member RAS oncogene family JBrowse link 8 87,545,106 87,570,545 RGD:14298760
G RAB34 RAB34, member RAS oncogene family JBrowse link 12 44,951,989 44,956,458 RGD:14298760
G RAB35 RAB35, member RAS oncogene family JBrowse link 14 40,124,318 40,141,261 RGD:14298760
G RAB36 RAB36, member RAS oncogene family JBrowse link 14 49,186,282 49,202,334 RGD:14298760
G RAB37 RAB37, member RAS oncogene family JBrowse link 12 6,484,535 6,535,665 RGD:14298760
G RAB38 RAB38, member RAS oncogene family JBrowse link 9 21,577,083 21,640,637 RGD:14298760
G RAB39A RAB39A, member RAS oncogene family JBrowse link 9 36,341,339 36,403,690 RGD:14298760
G RAB39B RAB39B, member RAS oncogene family JBrowse link X 125,520,764 125,528,253 RGD:14298760
G RAB3A RAB3A, member RAS oncogene family JBrowse link 2 59,603,090 59,609,773 RGD:14298760
G RAB3B RAB3B, member RAS oncogene family JBrowse link 6 160,194,488 160,255,635 RGD:14298760
G RAB3C RAB3C, member RAS oncogene family JBrowse link 16 37,411,931 37,729,583 RGD:14298760
G RAB3D RAB3D, member RAS oncogene family JBrowse link 2 70,023,470 70,035,679 RGD:14298760
G RAB40B RAB40B, member RAS oncogene family JBrowse link 12 492,298 516,965 RGD:14298760
G RAB40C RAB40C, member RAS oncogene family JBrowse link 3 41,140,557 41,160,101 RGD:14298760
G RAB42 RAB42, member RAS oncogene family JBrowse link 6 85,603,039 85,605,045 RGD:14298760
G RAB43 RAB43, member RAS oncogene family JBrowse link 13 71,564,250 71,596,318 RGD:14298760
G RAB44 RAB44, member RAS oncogene family JBrowse link 7 32,372,606 32,402,282 RGD:14298760
G RAB4A RAB4A, member RAS oncogene family JBrowse link 14 60,481,484 60,528,549 RGD:14298760
G RAB4B RAB4B, member RAS oncogene family JBrowse link 6 48,989,080 49,010,042 RGD:14298760
G RAB5A RAB5A, member RAS oncogene family JBrowse link 13 6,905,302 6,940,165 RGD:14298760
G RAB5B RAB5B, member RAS oncogene family JBrowse link 5 21,373,333 21,392,729 RGD:14298760
G RAB5C RAB5C, member RAS oncogene family JBrowse link 12 20,613,991 20,635,952 RGD:14298760
G RAB6A RAB6A, member RAS oncogene family JBrowse link 9 8,137,901 8,199,212 RGD:14298760
G RAB6B RAB6B, member RAS oncogene family JBrowse link 13 75,012,267 75,075,324 RGD:14298760
G RAB7A RAB7A, member RAS oncogene family JBrowse link 13 71,777,422 71,886,758 RGD:14298760
G RAB7B RAB7B, member RAS oncogene family JBrowse link 9 66,635,636 66,666,034 RGD:14298760
G RAB8A RAB8A, member RAS oncogene family JBrowse link 2 61,430,680 61,450,351 RGD:14298760
G RAB8B RAB8B, member RAS oncogene family JBrowse link 1 108,772,851 108,840,222 RGD:14298760
G RAB9A RAB9A, member RAS oncogene family JBrowse link X 10,328,085 10,349,399 RGD:14298760
G RAB9B RAB9B, member RAS oncogene family JBrowse link X 84,721,269 84,733,000 RGD:14298760
G RABL2B RAB, member of RAS oncogene family like 2B JBrowse link 5 10,346 20,499 RGD:14298760
G RABL3 RAB, member of RAS oncogene family like 3 JBrowse link 13 139,609,164 139,653,951 RGD:14298760
G RAC1 Rac family small GTPase 1 JBrowse link 3 4,781,776 4,803,510 RGD:14298760
G RAC2 Rac family small GTPase 2 JBrowse link 5 10,553,986 10,571,082 RGD:14298760
G RAC3 Rac family small GTPase 3 JBrowse link 12 981,072 984,222 RGD:14298760
G RALA RAS like proto-oncogene A JBrowse link 18 54,548,523 54,630,746 RGD:14298760
G RALB RAS like proto-oncogene B JBrowse link 15 31,064,341 31,118,437 RGD:14298760
G RAN RAN, member RAS oncogene family JBrowse link 14 24,312,810 24,318,024 RGD:14298760
G RAP1A RAP1A, member of RAS oncogene family JBrowse link 4 108,675,537 108,750,952 RGD:14298760
G RAP1B RAP1B, member of RAS oncogene family JBrowse link 5 32,910,181 32,961,972 RGD:14298760
G RAP2A RAP2A, member of RAS oncogene family JBrowse link 11 66,679,162 66,718,565 RGD:14298760
G RAP2B RAP2B, member of RAS oncogene family JBrowse link 13 93,308,112 93,308,663 RGD:14298760
G RAP2C RAP2C, member of RAS oncogene family JBrowse link X 108,332,623 108,348,432 RGD:14298760
G RASD1 ras related dexamethasone induced 1 JBrowse link 12 60,922,466 60,924,255 RGD:14298760
G RASD2 RASD family member 2 RGD:14298760
G RASEF RAS and EF-hand domain containing JBrowse link 10 31,929,121 32,012,183 RGD:14298760
G RASL10A RAS like family 10 member A JBrowse link 14 46,455,441 46,457,977 RGD:14298760
G RASL10B RAS like family 10 member B JBrowse link 12 39,783,725 39,795,283 RGD:14298760
G RASL11A RAS like family 11 member A JBrowse link 11 4,746,408 4,748,895 RGD:14298760
G RASL11B RAS like family 11 member B JBrowse link 8 39,703,399 39,708,174 RGD:14298760
G RASL12 RAS like family 12 JBrowse link 1 163,089,440 163,104,027 RGD:14298760
G REM1 RRAD and GEM like GTPase 1 JBrowse link 17 35,208,344 35,218,771 RGD:14298760
G REM2 RRAD and GEM like GTPase 2 JBrowse link 7 76,141,015 76,149,162 RGD:14298760
G RERG RAS like estrogen regulated growth inhibitor JBrowse link 5 57,349,386 57,462,813 RGD:14298760
G RERGL RERG like JBrowse link 5 54,939,384 54,952,059 RGD:14298760
G RHEB Ras homolog, mTORC1 binding JBrowse link 18 5,779,439 5,821,839 RGD:14298760
G RHEBL1 RHEB like 1 JBrowse link 5 15,094,398 15,097,785 RGD:14298760
G RHOA ras homolog family member A JBrowse link 13 31,918,484 31,991,207 RGD:14298760
G RHOB ras homolog family member B JBrowse link 3 117,773,400 117,777,569 RGD:14298760
G RHOBTB1 Rho related BTB domain containing 1 JBrowse link 14 64,326,461 64,465,331 RGD:14298760
G RHOBTB3 Rho related BTB domain containing 3 JBrowse link 2 102,334,747 102,395,134 RGD:14298760
G RHOC ras homolog family member C JBrowse link 4 107,731,713 107,737,705 RGD:14298760
G RHOD ras homolog family member D JBrowse link 2 5,392,546 5,404,214 RGD:14298760
G RHOF ras homolog family member F, filopodia associated JBrowse link 14 30,886,053 30,908,048 RGD:14298760
G RHOG ras homolog family member G JBrowse link 9 6,283,558 6,295,376 RGD:14298760
G RHOH ras homolog family member H JBrowse link 8 31,321,005 31,372,366 RGD:14298760
G RHOJ ras homolog family member J JBrowse link 1 194,761,588 194,843,867 RGD:14298760
G RHOQ ras homolog family member Q JBrowse link 3 93,970,545 94,012,660 RGD:14298760
G RHOT1 ras homolog family member T1 JBrowse link 12 42,711,231 42,783,471 RGD:14298760
G RHOT2 ras homolog family member T2 JBrowse link 3 41,100,876 41,106,370 RGD:14298760
G RHOU ras homolog family member U JBrowse link 14 60,667,104 60,677,582 RGD:14298760
G RHOV ras homolog family member V JBrowse link 1 130,443,602 130,445,664 RGD:14298760
G RIT1 Ras like without CAAX 1 JBrowse link 4 94,117,721 94,127,882 RGD:14298760
G RND1 Rho family GTPase 1 JBrowse link 5 14,914,652 14,922,032 RGD:14298760
G RND2 Rho family GTPase 2 JBrowse link 12 19,866,597 19,870,205 RGD:14298760
G RND3 Rho family GTPase 3 JBrowse link 15 1,715,589 1,732,605 RGD:14298760
G RNF112 ring finger protein 112 JBrowse link 12 60,117,452 60,124,071 RGD:14298760
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link 6 27,601,692 27,605,127 RGD:14298760
G RRAGA Ras related GTP binding A JBrowse link 1 203,772,063 203,774,580 RGD:14298760
G RRAGB Ras related GTP binding B JBrowse link X 48,286,584 48,330,196 RGD:14298760
G RRAGC Ras related GTP binding C JBrowse link 6 94,785,906 94,803,017 RGD:14298760
G RRAGD Ras related GTP binding D JBrowse link 1 57,374,047 57,424,058 RGD:14298760
G RRAS RAS related JBrowse link 6 54,680,596 54,684,714 RGD:14298760
G RRAS2 RAS related 2 JBrowse link 2 44,890,129 44,961,003 RGD:14298760
G SAR1A secretion associated Ras related GTPase 1A JBrowse link 14 73,090,936 73,108,209 RGD:14298760
G SAR1B secretion associated Ras related GTPase 1B JBrowse link 2 136,848,843 136,874,248 RGD:14298760
G SEPT12 septin 12 JBrowse link 3 37,604,669 37,617,336 RGD:14298760
G SEPTIN1 septin 1 JBrowse link 3 17,924,651 17,937,949 RGD:14298760
G SEPTIN10 septin 10 JBrowse link 3 46,484,138 46,546,677 RGD:14298760
G SEPTIN11 septin 11 JBrowse link 8 72,543,641 72,679,173 RGD:14298760
G SEPTIN14 septin 14 JBrowse link 3 16,988,590 17,026,258 RGD:14298760
G SEPTIN2 septin 2 JBrowse link 15 140,023,836 140,058,291 RGD:14298760
G SEPTIN3 septin 3 JBrowse link 5 6,631,750 6,657,837 RGD:14298760
G SEPTIN4 septin 4 JBrowse link 12 34,772,776 34,785,176 RGD:14298760
G SEPTIN5 septin 5 JBrowse link 14 51,252,815 51,260,851 RGD:14298760
G SEPTIN6 septin 6 JBrowse link X 98,033,212 98,106,082 RGD:14298760
G SEPTIN7 septin 7 JBrowse link 18 38,082,626 38,183,354 RGD:14298760
G SEPTIN8 septin 8 JBrowse link 2 135,077,158 135,104,484 RGD:14298760
G SEPTIN9 septin 9 JBrowse link 12 4,254,771 4,347,526 RGD:14298760
G SRP54 signal recognition particle 54 JBrowse link 7 64,829,625 64,877,574 RGD:14298760
G SRPRA SRP receptor subunit alpha JBrowse link 9 53,358,522 53,365,085 RGD:14298760
G TRIM23 tripartite motif containing 23 JBrowse link 16 44,103,339 44,146,291 RGD:14298760
G TSR1 TSR1 ribosome maturation factor JBrowse link 12 48,404,306 48,417,622 RGD:14298760
G TUBA1A tubulin alpha 1a JBrowse link 5 15,186,059 15,190,211 RGD:14298760
G TUBA1B tubulin alpha 1b JBrowse link 5 15,150,229 15,153,620 RGD:14298760
G TUBA4A tubulin alpha 4a JBrowse link 15 121,290,149 121,294,048 RGD:14298760
G TUBA8 tubulin alpha 8 JBrowse link 5 70,154,251 70,174,001 RGD:14298760
G TUBAL3 tubulin alpha like 3 JBrowse link 10 65,476,215 65,487,334 RGD:14298760
G TUBB tubulin beta class I JBrowse link 7 23,247,827 23,252,240 RGD:14298760
G TUBB1 tubulin beta 1 class VI JBrowse link 17 59,161,420 59,168,385 RGD:14298760
G TUBB2B tubulin, beta 2B class IIb JBrowse link 7 1,952,705 1,955,780 RGD:14298760
G TUBB4A tubulin beta 4A class IVa JBrowse link 2 72,599,244 72,605,362 RGD:14298760
G TUBB4B tubulin beta 4B class IVb RGD:14298760
G TUBB6 tubulin beta 6 class V JBrowse link 6 97,233,639 97,240,692 RGD:14298760
G TUBD1 tubulin delta 1 JBrowse link 12 36,079,939 36,111,306 RGD:14298760
G TUBE1 tubulin epsilon 1 JBrowse link 1 78,018,113 78,048,466 RGD:14298760
G TUBG1 tubulin gamma 1 RGD:14298760
G TUFM Tu translation elongation factor, mitochondrial JBrowse link 3 18,521,119 18,524,705 RGD:14298760
G UOX urate oxidase JBrowse link 6 129,343,632 129,374,833 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 13492
    catalytic activity 5060
      hydrolase activity 2156
        hydrolase activity, acting on acid anhydrides 711
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 709
            pyrophosphatase activity 706
              nucleoside-triphosphatase activity 661
                GTPase activity 259
                  GTPase activity, coupled + 0
                  GTPase motor activity + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.