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ONTOLOGY REPORT - ANNOTATIONS


Term:carbonate dehydratase activity
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Accession:GO:0004089 term browser browse the term
Definition:Catalysis of the reaction: H2CO3 = CO2 + H2O.
Synonyms:exact_synonym: carbonic anhydrase activity
 related_synonym: anhydrase activity;   carbonate anhydrase activity;   carbonate hydro-lyase (carbon-dioxide-forming);   carbonate hydro-lyase activity;   carbonic acid anhydrase activity;   carbonic anhydrase A;   carbonic dehydratase activity;   carboxyanhydrase activity
 xref: EC:4.2.1.1;   MetaCyc:CARBODEHYDRAT-RXN;   RHEA:10748;   reactome:R-HSA-1237045 "Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton";   reactome:R-HSA-1237047 "Carbonic anhydrase IV hydrates carbon dioxide to bicarbonate and a proton";   reactome:R-HSA-1237059 "Carbonic anhydrase IV dehydrates bicarbonate to water and carbon dioxide";   reactome:R-HSA-1237081 "Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide";   reactome:R-HSA-1475017 "Carbonic anhydrase dehydrates bicarbonate (plasma membrane)";   reactome:R-HSA-1475022 "Carbonic anhydrase dehydrates bicarbonate (cytosol)";   reactome:R-HSA-1475025 "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)";   reactome:R-HSA-1475026 "Carbonic anhydrase hydrates carbon dioxide (cytosol)";   reactome:R-HSA-1475028 "Carbonic anhydrase dehydrates bicarbonate (mitochondria)";   reactome:R-HSA-1475032 "Carbonic anhydrase hydrates carbon dioxide (mitochondria)";   reactome:R-HSA-1475435 "Carbonic anhydrase I/II hydrates carbon dioxide";   reactome:R-HSA-1475436 "Carbonic anhydrase I/II dehydrates bicarbonate"


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carbonate dehydratase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca11 carbonic anhydrase 11 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:101,682,009...101,687,358
Ensembl chr 1:101,682,172...101,687,293
JBrowse link
G Ca12 carbonic anhydrase 12 IBA
ISO
PMID:21873635
(MGI:3037519|PMID:14660577)
RGD PMID:14660577, PMID:21873635 MGI:3037519, RGD:13792537 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Ca13 carbonic anhydrase 13 IBA
ISO
PMID:21873635
(MGI:3763759|PMID:14600151)
RGD PMID:14600151, PMID:21873635 MGI:3763759, RGD:13792537 NCBI chr 2:88,282,961...88,314,254
Ensembl chr 2:88,282,961...88,314,254
JBrowse link
G Ca14 carbonic anhydrase 14 IBA
ISO
PMID:21873635
(MGI:3037519|PMID:14660577)
RGD PMID:14660577, PMID:21873635 MGI:3037519, RGD:13792537 NCBI chr 2:198,010,142...198,017,635
Ensembl chr 2:198,010,349...198,016,898
JBrowse link
G Ca3 carbonic anhydrase 3 TAS RGD PMID:10900145 RGD:634677 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca4 carbonic anhydrase 4 IDA
ISO
IEA
IBA
(MGI:3037519|PMID:14660577), (MGI:3696913|PMID:16083424)
GO_REF:0000003
PMID:21873635
RGD
UniProt
PMID:14660577, PMID:16083424, PMID:1533109, PMID:21873635 GO_REF:0000003, MGI:3037519, MGI:3696913, RGD:1600753, RGD:13792537 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Ca5a carbonic anhydrase 5A IDA
ISO
IBA
(MGI:1889881|PMID:10677517), (MGI:3763759|PMID:14600151), (MGI:68736|PMID:7929150)
PMID:21873635
RGD PMID:7929150, PMID:10677517, PMID:14600151, PMID:7937950, PMID:21873635 MGI:1889881, MGI:3763759, MGI:68736, RGD:69789, RGD:13792537 NCBI chr19:54,731,829...54,761,697
Ensembl chr19:54,731,859...54,761,670
JBrowse link
G Ca5b carbonic anhydrase 5B IBA
ISO
PMID:21873635
(MGI:1889881|PMID:10677517)
RGD PMID:10677517, PMID:21873635 MGI:1889881, RGD:13792537 NCBI chr  X:32,232,106...32,291,124
Ensembl chr  X:32,232,142...32,292,072
JBrowse link
G Ca6 carbonic anhydrase 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:167,226,246...167,244,786
Ensembl chr 5:167,226,246...167,244,786
JBrowse link
G Ca8 carbonic anhydrase 8 IEA GO_REF:0000002
GO_REF:0000003
InterPro
UniProt
GO_REF:0000002, GO_REF:0000003 NCBI chr 5:21,249,018...21,345,810
Ensembl chr 5:21,249,020...21,345,810
JBrowse link
G Ca9 carbonic anhydrase 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Car1 carbonic anhydrase 1 ISO
IBA
(PMID:7758465)
PMID:21873635
RGD PMID:7758465, PMID:21873635 RGD:13792537 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car10 carbonic anhydrase 10 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:80,790,151...81,297,621
Ensembl chr10:80,790,168...81,296,363
JBrowse link
G Car15 carbonic anhydrase 15 IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr11:87,293,827...87,298,690
Ensembl chr11:87,295,182...87,298,775
JBrowse link
G Car2 carbonic anhydrase 2 IDA
ISO
IBA
MGI:2135646 (MGI:3037519|PMID:14660577), (MGI:5506965|PMID:23881097)
PMID:21873635
(PMID:7758465)
RGD PMID:7758465, PMID:14660577, PMID:23881097, PMID:6425289, PMID:21873635 MGI:3037519, MGI:5506965, RGD:1600729, RGD:13792537 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Car7 carbonic anhydrase 7 ISO MGI:5543604 (MGI:5506965|PMID:23881097) RGD PMID:23881097 MGI:5506965 NCBI chr19:636,545...645,935
Ensembl chr19:636,545...645,937
JBrowse link
G LOC103693605 carbonic anhydrase 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:87,758,422...87,764,111
Ensembl chr11:87,759,536...87,762,301
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 20457
    catalytic activity 6065
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            carbonate dehydratase activity 17
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.