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ONTOLOGY REPORT - ANNOTATIONS


Term:cystathionine beta-synthase activity
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Accession:GO:0004122 term browser browse the term
Definition:Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
Synonyms:related_synonym: L-serine hydro-lyase (adding homocysteine);   L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming);   beta-thionase activity;   methylcysteine synthase activity;   serine sulfhydrase activity;   serine sulfhydrylase activity
 xref: EC:4.2.1.22;   MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN;   RHEA:10112;   Reactome:R-HSA-1614524 "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine"


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cystathionine beta-synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase TAS
IDA
ISO
(PMID:18776696), (PMID:19010420), (PMID:22985361), (PMID:23981774), (PMID:24416422), (PMID:7929220)
MGI:1857139 (MGI:1888627|PMID:10953023), (MGI:71081|PMID:7878023)
RGD PMID:7878023, PMID:7929220, PMID:10953023, PMID:18776696, PMID:19010420, PMID:22985361, PMID:23981774, PMID:24416422, PMID:12198128, PMID:9359866 MGI:1888627, MGI:71081, RGD:634704, RGD:1359024 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
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  molecular_function 20457
    catalytic activity 6065
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            cystathionine beta-synthase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.