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ONTOLOGY REPORT - ANNOTATIONS


Term:GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
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Accession:GO:0004377 term browser browse the term
Definition:Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
Synonyms:exact_synonym: GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity;   GDP-mannose-oligosaccharide-lipid mannosyltransferase activity;   GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity;   glycolipid 2-alpha-mannosyltransferase activity;   guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity;   oligosaccharide-lipid mannosyltransferase activity
 xref: EC:2.4.1.131;   MetaCyc:2.4.1.131-RXN;   RHEA:29523


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GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alg11 ALG11, alpha-1,2-mannosyltransferase JBrowse link 16 74,854,007 74,866,096 RGD:13792537

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  molecular_function 20377
    catalytic activity 6065
      transferase activity 2353
        transferase activity, transferring glycosyl groups 276
          transferase activity, transferring hexosyl groups 193
            mannosyltransferase activity 27
              glycolipid mannosyltransferase activity 6
                GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.