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Term:homogentisate 1,2-dioxygenase activity
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Accession:GO:0004411 term browser browse the term
Definition:Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+).
Synonyms:exact_synonym: homogentisate dioxygenase activity;   homogentisate oxidase activity;   homogentisate oxygenase activity;   homogentisate:oxygen 1,2-oxidoreductase (decyclizing);   homogentisic acid oxidase activity;   homogentisic acid oxygenase activity;   homogentisic oxygenase activity;   homogentisicase activity
 xref: EC:;   KEGG_REACTION:R02519;   MetaCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN;   RHEA:15449;   UM-BBD_reactionID:r0105;   reactome:R-HSA-71164 "homogentisate + O2 => maleylacetoacetate"

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homogentisate 1,2-dioxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hgd homogentisate 1, 2-dioxygenase JBrowse link 11 65,983,221 66,034,555 RGD:13792537

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  molecular_function 19678
    catalytic activity 6023
      oxidoreductase activity 848
        dioxygenase activity 79
          oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 27
            homogentisate 1,2-dioxygenase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.