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ONTOLOGY REPORT - ANNOTATIONS


Term:methylglutaconyl-CoA hydratase activity
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Accession:GO:0004490 term browser browse the term
Definition:Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O.
Synonyms:related_synonym: (S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming);   (S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity;   3-methylglutaconyl CoA hydratase activity;   methylglutaconase activity;   methylglutaconyl coenzyme A hydratase activity
 xref: EC:4.2.1.18;   KEGG_REACTION:R02085;   MetaCyc:METHYLGLUTACONYL-COA-HYDRATASE-RXN;   RHEA:21536;   reactome:R-HSA-70785 "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA"


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methylglutaconyl-CoA hydratase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr17:12,310,178...12,405,224
Ensembl chr17:12,310,214...12,405,205
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  molecular_function 20457
    catalytic activity 6065
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            methylglutaconyl-CoA hydratase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.