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Term:beta-galactosidase activity
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Accession:GO:0004565 term browser browse the term
Definition:Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.
Comment:Note that the inclusion of 'MetaCyc:BGALACT-PWY' is exceptional: normally MetaCyc pathway entries are database references for biological process terms, not molecular function terms. An exception was made in this case because the MetaCyc entry 'BGALACT-PWY' describes only one reaction, that catalyzed by beta-galactosidase.
Synonyms:exact_synonym: beta-D-galactanase activity;   beta-D-galactoside galactohydrolase activity;   beta-D-lactosidase activity;   beta-lactosidase activity;   exo-(1->4)-beta-D-galactanase activity;   trilactase activity
 related_synonym: S 2107;   hydrolact;   lactose hydrolysis;   lactozym;   maxilact;   oryzatym;   sumiklat
 xref: EC:;   MetaCyc:;   MetaCyc:BGALACT-PWY;   Reactome:R-HSA-2265534 "Defective GLB1 does not hydrolyse a glycosaminoglycan";   Reactome:R-HSA-9036061 "Defective GLB1 does not hydrolyse linker chain(2)";   reactome:R-HSA-1605624 "Beta-galactosidase hydrolyses GM1 to GM2";   reactome:R-HSA-1606312 "Beta-galactosidase can also hydrolyse globosides to form cerebrosides";   reactome:R-HSA-1630306 "GLB1 hydrolyses a glycosaminoglycan";   reactome:R-HSA-1793217 "Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase";   reactome:R-HSA-2090079 "GLB1 hydrolyses linker chain(2)"

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beta-galactosidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin2a beta-galactosidase-like protein JBrowse link 8 27,935,385 27,973,980 RGD:13792537
G Gba3 glucosylceramidase beta 3 JBrowse link 14 64,390,793 64,535,213 RGD:1624291
G Glb1 galactosidase, beta 1 JBrowse link 8 122,439,328 122,511,939 RGD:1598981
G Glb1l galactosidase, beta 1-like JBrowse link 9 82,400,457 82,410,970 RGD:13792537
G Glb1l2 galactosidase, beta 1-like 2 JBrowse link 8 27,805,139 27,853,080 RGD:13792537
G Glb1l3 galactosidase, beta 1-like 3 JBrowse link 8 27,865,452 27,907,726 RGD:1600115
G Psap prosaposin JBrowse link 20 29,831,302 29,856,876 RGD:1600115

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Term Annotations click to browse term
  molecular_function 19528
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on glycosyl bonds 135
          hydrolase activity, hydrolyzing O-glycosyl compounds 102
            galactosidase activity 9
              beta-galactosidase activity 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.