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ONTOLOGY REPORT - ANNOTATIONS


Term:phospholipase activity
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Accession:GO:0004620 term browser browse the term
Definition:Catalysis of the hydrolysis of a glycerophospholipid.
Synonyms:xref: EC:3.1.1;   reactome:R-HSA-6786650 "DDHD1,2 hydrolyse PA";   reactome:R-HSA-6792445 "LIPH, I hydrolyse PA to 2-acyl LPA"


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phospholipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034648.1 RGD:1600115
G Abhd12 abhydrolase domain containing 12, lysophospholipase JBrowse link 3 146,630,298 146,690,375 RGD:1600115
RGD:1624291
G Abhd16a abhydrolase domain containing 16A, phospholipase JBrowse link 20 5,080,070 5,094,935 RGD:1600115
RGD:1624291
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase JBrowse link 15 18,647,903 18,695,133 RGD:1624291
RGD:13792537
G Ddhd1 DDHD domain containing 1 JBrowse link 15 19,963,639 20,032,263 RGD:13792537
G Ddhd2 DDHD domain containing 2 JBrowse link 16 71,090,096 71,120,713 RGD:13792537
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:1624291
G Liph lipase H JBrowse link 11 82,680,167 82,732,145 RGD:1624291
RGD:13792537
G Lipi lipase I JBrowse link 11 13,960,246 13,999,869 RGD:1624291
RGD:13792537
G Lypla1 lysophospholipase 1 JBrowse link 5 14,559,333 14,588,447 RGD:1624291
G Napepld N-acyl phosphatidylethanolamine phospholipase D JBrowse link 4 9,965,323 10,004,650 RGD:1302835
G Pitpnm3 PITPNM family member 3 JBrowse link 10 58,618,679 58,722,679 RGD:13792537
G Pla1a phospholipase A1 member A JBrowse link 11 64,882,024 64,919,714 RGD:13792537
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1624291
G Plaat1 phospholipase A and acyltransferase 1 JBrowse link 11 75,125,951 75,145,868 RGD:13702198
RGD:1624291
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:1600115
RGD:13792537
G Plbd1 phospholipase B domain containing 1 JBrowse link 4 170,564,387 170,620,681 RGD:1600115
G Plbd2 phospholipase B domain containing 2 JBrowse link 12 41,600,005 41,619,779 RGD:1600115
G Pnliprp2 pancreatic lipase related protein 2 JBrowse link 1 279,896,973 279,927,600 RGD:2303166
RGD:13792537
RGD:1600115
RGD:1624291
G Sec23ip SEC23 interacting protein JBrowse link 1 200,167,075 200,210,362 RGD:13792537
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:13792537
G Smpd5 sphingomyelin phosphodiesterase 5 JBrowse link 7 117,351,694 117,354,241 RGD:13792537
1-acyl-2-lysophosphatidylserine acylhydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:1600115
acid sphingomyelin phosphodiesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:1624291
RGD:13792537
calcium-dependent phospholipase A2 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102546467 HERV-H LTR-associating protein 1-like JBrowse link 7 106,442,364 106,485,324 RGD:13792537
G Oc90 otoconin 90 JBrowse link 7 106,615,859 106,697,089 RGD:13792537
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:2303763
RGD:1624291
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:2303763
RGD:13792537
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:69933
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:13792537
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:13792537
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642483
RGD:13792537
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1624291
RGD:13792537
G Pla2g4c phospholipase A2 group IVC JBrowse link 1 75,440,035 75,481,995 RGD:13792537
G Pla2g4d phospholipase A2 group IVD JBrowse link 3 112,040,827 112,061,847 RGD:1624291
RGD:13792537
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:13792537
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
RGD:13792537
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:61698
RGD:13792537
calcium-dependent phospholipase C activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plch1 phospholipase C, eta 1 JBrowse link 2 154,256,382 154,468,166 RGD:1624291
calcium-independent phospholipase A2 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pla2g15 phospholipase A2, group XV JBrowse link 19 38,129,666 38,146,958 RGD:1304489
RGD:1624291
G Pla2g4c phospholipase A2 group IVC JBrowse link 1 75,440,035 75,481,995 RGD:1624291
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:729507
G Pla2g7 phospholipase A2 group VII JBrowse link 9 19,935,754 19,978,013 RGD:1624291
G Pnpla8 patatin-like phospholipase domain containing 8 JBrowse link 6 64,224,870 64,288,465 RGD:1624291
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:1624291
cardiolipin hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pld6 phospholipase D family, member 6 JBrowse link 10 46,142,313 46,145,774 RGD:1624291
glycosylphosphatidylinositol phospholipase D activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:632912
RGD:13792537
RGD:1624291
RGD:1600115
RGD:8553426
lysophospholipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd12 abhydrolase domain containing 12, lysophospholipase JBrowse link 3 146,630,298 146,690,375 RGD:1600115
RGD:1624291
G Abhd16a abhydrolase domain containing 16A, phospholipase JBrowse link 20 5,080,070 5,094,935 RGD:1624291
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 15 32,888,233 32,906,861 RGD:1624291
G Alkbh5 alkB homolog 5, RNA demethylase JBrowse link 10 46,906,314 46,927,759 RGD:1624291
G Aspg asparaginase JBrowse link 6 136,682,279 136,701,673 RGD:1299414
RGD:14695081
RGD:2303783
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:2313552
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 7 94,479,931 94,563,086 RGD:8553522
RGD:15090854
RGD:1624291
RGD:1600115
RGD:13792537
G Gde1 glycerophosphodiester phosphodiesterase 1 JBrowse link 1 188,367,550 188,407,125 RGD:1624291
RGD:1600115
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 JBrowse link 10 74,334,972 74,376,332 RGD:1600115
RGD:13792537
RGD:1624291
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 JBrowse link 1 198,199,032 198,209,178 RGD:1624291
RGD:13792537
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308772
G Lypla1 lysophospholipase 1 JBrowse link 5 14,559,333 14,588,447 RGD:633195
RGD:1624291
G Lypla2 lysophospholipase 2 JBrowse link 5 154,315,033 154,319,629 RGD:1624291
RGD:1600115
G Pla2g15 phospholipase A2, group XV JBrowse link 19 38,129,666 38,146,958 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1600115
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1624291
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:6903950
RGD:13792537
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:1624291
RGD:13792537
G Pnpla7 patatin-like phospholipase domain containing 7 JBrowse link 3 2,182,191 2,261,890 RGD:1624291
RGD:13792537
N-acylphosphatidylethanolamine-specific phospholipase D activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Napepld N-acyl phosphatidylethanolamine phospholipase D JBrowse link 4 9,965,323 10,004,650 RGD:1600115
RGD:1624291
RGD:13792537
G Pld1 phospholipase D1 JBrowse link 2 113,651,967 113,849,403 RGD:1600115
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:1600115
neutral sphingomyelin phosphodiesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1600115
RGD:1624291
phosphatidylinositol phospholipase C activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1624291
RGD:1600115
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:1624291
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:1582559
RGD:13792537
RGD:1624291
RGD:1600115
G Plcb2 phospholipase C, beta 2 JBrowse link 3 110,497,760 110,517,563 RGD:1624291
RGD:13792537
RGD:729588
RGD:1600115
G Plcb3 phospholipase C beta 3 JBrowse link 1 222,207,887 222,224,993 RGD:61699
RGD:13792537
RGD:1600115
G Plcb4 phospholipase C, beta 4 JBrowse link 3 128,601,163 128,971,720 RGD:1600115
RGD:13792537
G Plcd1 phospholipase C, delta 1 JBrowse link 8 127,753,514 127,782,070 RGD:2301017
RGD:13792537
RGD:1600115
G Plcd3 phospholipase C, delta 3 JBrowse link 10 91,164,778 91,186,067 RGD:13792537
G Plcd4 phospholipase C, delta 4 JBrowse link 9 81,816,395 81,844,364 RGD:633664
RGD:13792537
RGD:1600115
G Plce1 phospholipase C, epsilon 1 JBrowse link 1 257,156,023 257,465,440 RGD:68714
RGD:13792537
RGD:1624291
RGD:1600115
G Plcg1 phospholipase C, gamma 1 JBrowse link 3 156,727,642 156,758,307 RGD:1600115
RGD:13792537
RGD:1624291
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:69934
RGD:13792537
RGD:1624291
RGD:1600115
G Plch1 phospholipase C, eta 1 JBrowse link 2 154,256,382 154,468,166 RGD:13792537
G Plch2 phospholipase C, eta 2 JBrowse link 5 172,386,400 172,455,965 RGD:13792537
G Plcl1 phospholipase C-like 1 JBrowse link 9 62,016,112 62,349,244 RGD:1600115
G Plcl2 phospholipase C-like 2 JBrowse link 9 1,782,536 1,984,654 RGD:1600115
G Plcz1 phospholipase C, zeta 1 JBrowse link 4 174,125,072 174,181,524 RGD:1624291
RGD:13792537
phosphatidylserine 1-acylhydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:1600115
phospholipase A1 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:1624291
RGD:13792537
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308772
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:1624291
G Pla1a phospholipase A1 member A JBrowse link 11 64,882,024 64,919,714 RGD:1624291
G Plaat1 phospholipase A and acyltransferase 1 JBrowse link 11 75,125,951 75,145,868 RGD:1624291
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:12790655
RGD:1624291
G Plaat5 phospholipase A and acyltransferase 5 JBrowse link 1 222,907,159 222,937,643 RGD:1624291
phospholipase A2 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:1624291
RGD:13792537
G Lcat lecithin cholesterol acyltransferase JBrowse link 19 37,913,333 37,916,799 RGD:729077
G LOC102546467 HERV-H LTR-associating protein 1-like JBrowse link 7 106,442,364 106,485,324 RGD:13792537
G Oc90 otoconin 90 JBrowse link 7 106,615,859 106,697,089 RGD:13792537
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1582547
RGD:1600115
G Pla2g12a phospholipase A2, group XIIA JBrowse link 2 235,311,664 235,327,972 RGD:1624291
RGD:13792537
G Pla2g12b phospholipase A2, group XIIB JBrowse link 20 28,989,440 29,007,967 RGD:1600115
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:1302902
RGD:1624291
RGD:8553780
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:628361
RGD:13792537
RGD:1624291
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:1600115
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:13792537
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:1624291
RGD:13792537
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:1600115
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:633563
RGD:13792537
RGD:1624291
RGD:1600115
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1624291
RGD:13792537
G Pla2g4c phospholipase A2 group IVC JBrowse link 1 75,440,035 75,481,995 RGD:13792537
G Pla2g4d phospholipase A2 group IVD JBrowse link 3 112,040,827 112,061,847 RGD:1624291
RGD:13792537
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:1624291
RGD:13792537
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
RGD:13792537
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:1624291
RGD:13792537
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:1600115
G Plaat1 phospholipase A and acyltransferase 1 JBrowse link 11 75,125,951 75,145,868 RGD:1624291
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:12790655
RGD:1624291
G Plaat5 phospholipase A and acyltransferase 5 JBrowse link 1 222,907,159 222,937,643 RGD:1624291
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:6903950
RGD:13792537
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:1624291
G Proca1 protein interacting with cyclin A1 JBrowse link 10 65,454,451 65,469,491 RGD:1600115
phospholipase C activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plcb2 phospholipase C, beta 2 JBrowse link 3 110,497,760 110,517,563 RGD:729588
G Plcb3 phospholipase C beta 3 JBrowse link 1 222,207,887 222,224,993 RGD:61699
G Plcd1 phospholipase C, delta 1 JBrowse link 8 127,753,514 127,782,070 RGD:1624291
G Plce1 phospholipase C, epsilon 1 JBrowse link 1 257,156,023 257,465,440 RGD:1624291
RGD:1600115
G Plch2 phospholipase C, eta 2 JBrowse link 5 172,386,400 172,455,965 RGD:1624291
G Plcz1 phospholipase C, zeta 1 JBrowse link 4 174,125,072 174,181,524 RGD:1624291
phospholipase D activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam83b family with sequence similarity 83, member B JBrowse link 8 83,616,148 83,693,484 RGD:1624291
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:628519
G Pld1 phospholipase D1 JBrowse link 2 113,651,967 113,849,403 RGD:729596
RGD:1600115
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:729617
RGD:1600115
RGD:1624291
G Pld4 phospholipase D family, member 4 JBrowse link 6 137,323,713 137,331,231 RGD:1624291
sphingomyelin phosphodiesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:1600115
RGD:1624291
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:13792537
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link 20 46,212,070 46,215,183 RGD:634108
RGD:13792537
RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:13792537
G Smpd5 sphingomyelin phosphodiesterase 5 JBrowse link 7 117,351,694 117,354,241 RGD:1624291
RGD:13792537
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A JBrowse link 20 40,779,022 40,800,842 RGD:1624291
RGD:1600115
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B JBrowse link 5 150,925,150 150,946,994 RGD:1600115
sphingomyelin phosphodiesterase D activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smpd4 sphingomyelin phosphodiesterase 4 JBrowse link 11 87,522,971 87,546,687 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19527
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 781
          lipase activity 120
            phospholipase activity 92
              1-acyl-2-lysophosphatidylserine acylhydrolase activity 1
              N-acylphosphatidylethanolamine-specific phospholipase D activity 3
              cardiolipin hydrolase activity 1
              lysophospholipase activity 20
              phosphatidylserine 1-acylhydrolase activity 1
              phospholipase A1 activity 7
              phospholipase A2 activity + 31
              phospholipase C activity + 17
              phospholipase D activity + 6
              sphingomyelin phosphodiesterase D activity 1
              sphingomyelin phosphodiesterase activity + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.