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ONTOLOGY REPORT - ANNOTATIONS


Term:lysophospholipase activity
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Accession:GO:0004622 term browser browse the term
Definition:Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
Synonyms:exact_synonym: 2-lysophosphatidylcholine acylhydrolase activity;   lecithinase B activity;   lecitholipase activity;   lysolecithinase activity;   lysophosphatidase activity;   lysophosphatidylcholine hydrolase activity;   phospholipase B activity
 related_synonym: lysophopholipase L2;   lysophospholipase A1;   phosphatidase B
 alt_id: GO:0045126
 xref: EC:3.1.1.5;   MetaCyc:LYSOPHOSPHOLIPASE-RXN;   RHEA:15177;   reactome:R-HSA-1482545 "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482571 "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482612 "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482629 "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-1482685 "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482696 "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-6814254 "PNPLA6 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814766 "GDPD1 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814778 "GDPD3 hydrolyzes LysoPtdCho";   reactome:R-HSA-8847912 "PNPLA7 hydrolyzes LysoPtdCho"


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lysophospholipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABHD12 abhydrolase domain containing 12, lysophospholipase JBrowse link 23 1,496,183 1,562,738 RGD:13508589
G ABHD12B abhydrolase domain containing 12B JBrowse link 8 27,239,900 27,264,615 RGD:13508589
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 8 2,997,112 3,011,524 RGD:13508589
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 13 18,586,886 18,697,339 RGD:13508589
G GDE1 glycerophosphodiester phosphodiesterase 1 JBrowse link 6 25,740,741 25,765,404 RGD:13508589
G GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 JBrowse link 9 33,773,365 33,827,131 RGD:13508589
G GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 JBrowse link 6 18,103,273 18,108,818 RGD:13508589
G MCOLN1 mucolipin 1 JBrowse link 20 52,318,411 52,327,389 RGD:13508589
G PLA2G15 phospholipase A2 group XV JBrowse link 5 81,269,914 81,280,700 RGD:13508589
G PLA2G4A phospholipase A2 group IVA JBrowse link 7 19,804,412 19,955,215 RGD:13508589
G PLA2G4F phospholipase A2 group IVF JBrowse link 30 9,150,325 9,165,610 RGD:13508589
G PLB1 phospholipase B1 JBrowse link 17 22,420,679 22,558,318 RGD:13508589
G PNPLA6 patatin like phospholipase domain containing 6 JBrowse link 20 52,327,547 52,349,006 RGD:13508589
G PNPLA7 patatin like phospholipase domain containing 7 JBrowse link 9 48,221,754 48,286,352 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 13479
    catalytic activity 5058
      hydrolase activity 2159
        hydrolase activity, acting on ester bonds 630
          carboxylic ester hydrolase activity 110
            lysophospholipase activity 14
Path 2
Term Annotations click to browse term
  molecular_function 13479
    catalytic activity 5058
      hydrolase activity 2159
        hydrolase activity, acting on ester bonds 630
          lipase activity 102
            phospholipase activity 80
              lysophospholipase activity 14
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.