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ONTOLOGY REPORT - ANNOTATIONS


Term:lysophospholipase activity
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Accession:GO:0004622 term browser browse the term
Definition:Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
Synonyms:exact_synonym: 2-lysophosphatidylcholine acylhydrolase activity;   lecithinase B activity;   lecitholipase activity;   lysolecithinase activity;   lysophosphatidase activity;   lysophosphatidylcholine hydrolase activity;   phospholipase B activity
 related_synonym: lysophopholipase L2;   lysophospholipase A1;   phosphatidase B
 alt_id: GO:0045126
 xref: EC:3.1.1.5;   MetaCyc:LYSOPHOSPHOLIPASE-RXN;   RHEA:15177;   reactome:R-HSA-1482545 "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482571 "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482612 "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482629 "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-1482685 "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482696 "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-6814254 "PNPLA6 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814766 "GDPD1 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814778 "GDPD3 hydrolyzes LysoPtdCho";   reactome:R-HSA-8847912 "PNPLA7 hydrolyzes LysoPtdCho"


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lysophospholipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABHD12 abhydrolase domain containing 12, lysophospholipase JBrowse link 20 25,294,743 25,390,835 RGD:2290271
G ABHD12B abhydrolase domain containing 12B JBrowse link 14 50,872,053 50,904,970 RGD:2290271
G ABHD16A abhydrolase domain containing 16A, phospholipase JBrowse link 6 31,686,955 31,703,324 RGD:2290271
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 14 22,598,238 22,612,864 RGD:2290271
G ASPG asparaginase JBrowse link 14 104,085,658 104,115,582 RGD:2290271
G CLC Charcot-Leyden crystal galectin JBrowse link 19 39,731,255 39,738,029 RGD:2290271
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 8 119,557,085 119,673,404 RGD:2290271
G GDE1 glycerophosphodiester phosphodiesterase 1 JBrowse link 16 19,501,693 19,522,098 RGD:2290271
G GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 JBrowse link 17 59,220,470 59,275,970 RGD:2290271
G GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 JBrowse link 16 30,104,810 30,113,537 RGD:2290271
G JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough JBrowse link 15 41,828,085 41,848,148 RGD:2290271
G LGALS13 galectin 13 JBrowse link 19 39,602,411 39,607,474 RGD:2290271
G LIPC lipase C, hepatic type JBrowse link 15 58,410,457 58,569,844 RGD:2290271
G LYPLA1 lysophospholipase 1 JBrowse link 8 54,046,367 54,102,017 RGD:2290271
G LYPLA2 lysophospholipase 2 JBrowse link 1 23,790,789 23,795,539 RGD:2290271
G LYPLAL1 lysophospholipase like 1 JBrowse link 1 219,173,831 219,445,121 RGD:2290271
G MGLL monoglyceride lipase JBrowse link 3 127,689,062 127,823,250 RGD:2290271
G PLA2G15 phospholipase A2 group XV JBrowse link 16 68,245,371 68,261,062 RGD:2290271
G PLA2G4A phospholipase A2 group IVA JBrowse link 1 186,828,949 186,988,981 RGD:2290271
G PLA2G4B phospholipase A2 group IVB JBrowse link 15 41,838,813 41,848,148 RGD:2290271
G PLA2G4C phospholipase A2 group IVC JBrowse link 19 48,047,843 48,111,383 RGD:2290271
G PLA2G4F phospholipase A2 group IVF JBrowse link 15 42,139,034 42,156,636 RGD:2290271
G PLA2G6 phospholipase A2 group VI JBrowse link 22 38,111,495 38,181,830 RGD:2290271
G PLB1 phospholipase B1 JBrowse link 2 28,488,578 28,644,142 RGD:2290271
G PNPLA6 patatin like phospholipase domain containing 6 JBrowse link 19 7,534,164 7,561,767 RGD:2290271
G PNPLA7 patatin like phospholipase domain containing 7 JBrowse link 9 137,459,399 137,550,666 RGD:2290271
G PNPLA8 patatin like phospholipase domain containing 8 JBrowse link 7 108,470,417 108,528,178 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17949
    catalytic activity 5934
      hydrolase activity 2595
        hydrolase activity, acting on ester bonds 785
          carboxylic ester hydrolase activity 149
            lysophospholipase activity 27
Path 2
Term Annotations click to browse term
  molecular_function 17949
    catalytic activity 5934
      hydrolase activity 2595
        hydrolase activity, acting on ester bonds 785
          lipase activity 137
            phospholipase activity 112
              lysophospholipase activity 27
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.