Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:lysophospholipase activity
go back to main search page
Accession:GO:0004622 term browser browse the term
Definition:Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
Synonyms:exact_synonym: 2-lysophosphatidylcholine acylhydrolase activity;   lecithinase B activity;   lecitholipase activity;   lysolecithinase activity;   lysophosphatidase activity;   lysophosphatidylcholine hydrolase activity;   phospholipase B activity
 related_synonym: lysophopholipase L2;   lysophospholipase A1;   phosphatidase B
 alt_id: GO:0045126
 xref: EC:3.1.1.5;   MetaCyc:LYSOPHOSPHOLIPASE-RXN;   RHEA:15177;   reactome:R-HSA-1482545 "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482571 "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482612 "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482629 "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-1482685 "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482696 "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-6814254 "PNPLA6 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814766 "GDPD1 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814778 "GDPD3 hydrolyzes LysoPtdCho";   reactome:R-HSA-8847912 "PNPLA7 hydrolyzes LysoPtdCho"


show annotations for term's descendants       view all columns           Sort by:
 
lysophospholipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABHD12 abhydrolase domain containing 12, lysophospholipase JBrowse link 17 30,997,477 31,056,307 RGD:14298760
G ABHD12B abhydrolase domain containing 12B JBrowse link 1 180,635,479 180,662,432 RGD:14298760
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 7 76,396,548 76,431,836 RGD:14298760
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 4 19,319,815 19,433,492 RGD:14298760
G GDE1 glycerophosphodiester phosphodiesterase 1 JBrowse link 3 26,190,261 26,205,851 RGD:14298760
G GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 JBrowse link 12 35,481,194 35,527,588 RGD:14298760
G GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 JBrowse link 3 18,282,574 18,291,307 RGD:14298760
G LOC100739561 glycerophosphodiester phosphodiesterase domain-containing protein 1 RGD:14298760
G LYPLA1 lysophospholipase 1 JBrowse link 4 77,083,624 77,102,407 RGD:14298760
G LYPLA2 lysophospholipase 2 JBrowse link 6 81,601,492 81,605,914 RGD:14298760
G PLA2G4A phospholipase A2 group IVA JBrowse link 9 127,853,581 128,164,825 RGD:14298760
G PLA2G4F phospholipase A2 group IVF JBrowse link 1 129,200,568 129,218,417 RGD:14298760
G PNPLA6 patatin like phospholipase domain containing 6 JBrowse link 2 71,577,165 71,602,756 RGD:14298760
G PNPLA7 patatin like phospholipase domain containing 7 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14186
    catalytic activity 5169
      hydrolase activity 2197
        hydrolase activity, acting on ester bonds 657
          carboxylic ester hydrolase activity 115
            lysophospholipase activity 14
Path 2
Term Annotations click to browse term
  molecular_function 14186
    catalytic activity 5169
      hydrolase activity 2197
        hydrolase activity, acting on ester bonds 657
          lipase activity 108
            phospholipase activity 85
              lysophospholipase activity 14
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.