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ONTOLOGY REPORT - ANNOTATIONS


Term:lysophospholipase activity
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Accession:GO:0004622 term browser browse the term
Definition:Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
Synonyms:exact_synonym: 2-lysophosphatidylcholine acylhydrolase activity;   lecithinase B activity;   lecitholipase activity;   lysolecithinase activity;   lysophosphatidase activity;   lysophosphatidylcholine hydrolase activity;   phospholipase B activity
 related_synonym: lysophopholipase L2;   lysophospholipase A1;   phosphatidase B
 alt_id: GO:0045126
 xref: EC:3.1.1.5;   MetaCyc:LYSOPHOSPHOLIPASE-RXN;   RHEA:15177;   reactome:R-HSA-1482545 "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482571 "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C";   reactome:R-HSA-1482612 "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482629 "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-1482685 "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]";   reactome:R-HSA-1482696 "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C";   reactome:R-HSA-6814254 "PNPLA6 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814766 "GDPD1 hydrolyzes LysoPtdCho";   reactome:R-HSA-6814778 "GDPD3 hydrolyzes LysoPtdCho";   reactome:R-HSA-8847912 "PNPLA7 hydrolyzes LysoPtdCho"


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lysophospholipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd12 abhydrolase domain containing 12, lysophospholipase JBrowse link 3 146,630,298 146,690,375 RGD:1600115
RGD:13792537
RGD:1624291
G Abhd12b abhydrolase domain containing 12B JBrowse link 6 92,568,975 92,596,327 RGD:13792537
G Abhd16a abhydrolase domain containing 16A, phospholipase JBrowse link 20 5,080,070 5,094,935 RGD:1624291
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 15 32,888,233 32,906,861 RGD:1624291
RGD:13792537
G Alkbh5 alkB homolog 5, RNA demethylase JBrowse link 10 46,906,314 46,927,759 RGD:1624291
G Aspg asparaginase JBrowse link 6 136,682,279 136,701,673 RGD:1299414
RGD:14695081
RGD:2303783
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:2313552
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 7 94,479,931 94,563,086 RGD:8553522
RGD:15090854
RGD:1624291
RGD:1600115
RGD:13792537
G Gde1 glycerophosphodiester phosphodiesterase 1 JBrowse link 1 188,367,550 188,407,125 RGD:1624291
RGD:1600115
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 JBrowse link 10 74,334,972 74,376,332 RGD:1600115
RGD:13792537
RGD:1624291
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 JBrowse link 1 198,199,032 198,209,178 RGD:1624291
RGD:13792537
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308772
G Lypla1 lysophospholipase 1 JBrowse link 5 14,559,333 14,588,447 RGD:633195
RGD:1624291
G Lypla2 lysophospholipase 2 JBrowse link 5 154,315,033 154,319,629 RGD:1624291
RGD:1600115
G Pla2g15 phospholipase A2, group XV JBrowse link 19 38,129,666 38,146,958 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1600115
RGD:1624291
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1624291
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:1600115
RGD:1624291
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:6903950
RGD:13792537
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:1624291
RGD:13792537
G Pnpla7 patatin-like phospholipase domain containing 7 JBrowse link 3 2,182,191 2,261,890 RGD:1624291
RGD:1600115
RGD:13792537
G Pnpla8 patatin-like phospholipase domain containing 8 JBrowse link 6 64,224,870 64,288,465 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19678
    catalytic activity 6023
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 790
          carboxylic ester hydrolase activity 163
            lysophospholipase activity 23
Path 2
Term Annotations click to browse term
  molecular_function 19678
    catalytic activity 6023
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 790
          lipase activity 126
            phospholipase activity 97
              lysophospholipase activity 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.