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ONTOLOGY REPORT - ANNOTATIONS


Term:phospholipase D activity
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Accession:GO:0004630 term browser browse the term
Definition:Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.
Synonyms:exact_synonym: choline phosphatase activity;   lecithinase D activity;   lipophosphodiesterase II activity;   phosphatidylcholine phosphatidohydrolase activity
 xref: EC:3.1.4.4;   MetaCyc:PHOSCHOL-RXN;   reactome:R-HSA-1483142 "PC is transphosphatidylated to PG by PLD1-4/6";   reactome:R-HSA-1483182 "PC is hydrolyzed to PA and choline by PLD1/2";   reactome:R-HSA-2029471 "Hydrolysis of PC to PA by PLD"


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phospholipase D activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam83b family with sequence similarity 83, member B JBrowse link 8 83,616,148 83,693,484 RGD:1624291
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:628519
G Pld1 phospholipase D1 JBrowse link 2 113,651,967 113,849,403 RGD:729596
RGD:1600115
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:729617
RGD:1600115
RGD:1624291
G Pld4 phospholipase D family, member 4 JBrowse link 6 137,323,713 137,331,231 RGD:1624291
glycosylphosphatidylinositol phospholipase D activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:632912
RGD:13792537
RGD:1624291
RGD:1600115
RGD:8553426

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  molecular_function 19527
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 781
          phosphoric ester hydrolase activity 369
            phosphoric diester hydrolase activity 92
              phospholipase D activity 6
                glycosylphosphatidylinositol phospholipase D activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.