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ONTOLOGY REPORT - ANNOTATIONS


Term:phosphopyruvate hydratase activity
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Accession:GO:0004634 term browser browse the term
Definition:Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
Synonyms:exact_synonym: 2-phospho-D-glycerate-hydrolase activity
 narrow_synonym: nervous-system specific enolase
 related_synonym: 14-3-2-protein;   2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming);   2-phospho-D-glycerate hydro-lyase activity;   2-phosphoglycerate dehydratase activity;   2-phosphoglycerate enolase activity;   2-phosphoglyceric dehydratase activity;   enolase activity;   gamma-enolase activity;   phosphoenolpyruvate hydratase activity
 xref: EC:4.2.1.11;   MetaCyc:2PGADEHYDRAT-RXN;   RHEA:10164;   reactome:R-HSA-70494 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate";   reactome:R-HSA-71660 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O"


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phosphopyruvate hydratase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07029675.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:44,658,634...44,659,707 JBrowse link
G AABR07052523.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 3:59,408,546...59,410,211 JBrowse link
G AABR07067976.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 9:74,960,255...74,960,640 JBrowse link
G Eno1 enolase 1 IDA
IBA
ISO
PMID:21873635
(PMID:29775581), (PMID:3529090)
PMID:7964722
(MGI:MGI:55148|PMID:7323947)
RGD PMID:3529090, PMID:7323947, PMID:29775581, PMID:15041191, PMID:21873635, PMID:7964722 MGI:MGI:55148, RGD:2302788, RGD:13792537, RGD:12792993 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno1-ps1 enolase 1, (alpha), pseudogene 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:59,408,531...59,410,209 JBrowse link
G Eno2 enolase 2 TAS
IBA
IDA
PMID:21873635
PMID:7964722
RGD
GO_Central
CAFA
PMID:2865729, PMID:21873635, PMID:7964722, PMID:8255543, PMID:15720133, PMID:15041191 RGD:1298905, RGD:13792537, RGD:12792993, RGD:2302804, RGD:2302795, RGD:2302788 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Eno3 enolase 3 IDA
IBA
ISO
PMID:21873635
(MGI:MGI:3852306|PMID:17023274)
RGD PMID:17023274, PMID:8594891, PMID:21873635 MGI:MGI:3852306, RGD:2301765, RGD:13792537 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Eno4 enolase 4 ISO
IBA
MGI:MGI:4127723 (MGI:MGI:5516566|PMID:23446454)
PMID:21873635
RGD PMID:23446454, PMID:21873635 MGI:MGI:5516566, RGD:13792537 NCBI chr 1:280,097,061...280,129,750
Ensembl chr 1:280,103,695...280,127,073
JBrowse link
G LOC100911625 gamma-enolase-like IDA
IBA
PMID:7964722
PMID:21873635
CAFA
GO_Central
PMID:7964722, PMID:21873635 RGD:12792993, RGD:13792537 NCBI chr 9:20,251,564...20,260,465
Ensembl chr 9:20,251,521...20,260,505
JBrowse link
G RGD1559534 similar to Alpha enolase (2-phospho-D-glycerate hydro-lyase) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:44,658,634...44,662,983 JBrowse link

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Term Annotations click to browse term
  molecular_function 20457
    catalytic activity 6065
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            phosphopyruvate hydratase activity 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.