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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor kinase activity
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Accession:GO:0004703 term browser browse the term
Definition:Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate.
Synonyms:exact_synonym: G protein coupled receptor phosphorylating protein kinase activity;   GPCR phosphorylating protein kinase activity
 related_synonym: ATP:G-protein-coupled receptor phosphotransferase activity;   GPCR kinase activity;   GPCRK;   GRK4;   GRK5;   GRK6;   STK16
 alt_id: GO:0004678
 xref: EC:2.7.11.16;   RHEA:12008


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G protein-coupled receptor kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk1 G protein-coupled receptor kinase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:81,153,489...81,165,442
Ensembl chr16:81,153,489...81,165,442
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IDA
ISO
IEA
MGI:2180127 (MGI:3032880|PMID:14712229), (MGI:59809|PMID:1869533), (MGI:83995|PMID:8917529)
GO_REF:0000107
RGD
Ensembl
PMID:1869533, PMID:8917529, PMID:14712229, PMID:1403099 GO_REF:0000107, MGI:3032880, MGI:59809, MGI:83995, RGD:632163 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IDA
ISO
IEA
(MGI:59809|PMID:1869533)
GO_REF:0000107
GO_REF:0000002
RGD
Ensembl
InterPro
PMID:1869533, PMID:1403099 GO_REF:0000002, GO_REF:0000107, MGI:59809, RGD:632163 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr14:81,261,708...81,339,516
Ensembl chr14:81,265,672...81,339,526
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IC
IEA
GO_REF:0000002 InterPro PMID:8626574 GO_REF:0000002, RGD:61618 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 IDA
IEA
GO_REF:0000002 InterPro PMID:12810562 GO_REF:0000002, RGD:1299124 NCBI chr17:9,705,917...9,721,921
Ensembl chr17:9,703,453...9,721,574
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    catalytic activity 6065
      catalytic activity, acting on a protein 2382
        protein kinase activity 596
          protein serine/threonine kinase activity 429
            G protein-coupled receptor kinase activity 6
Path 2
Term Annotations click to browse term
  molecular_function 20457
    catalytic activity 6065
      transferase activity 2352
        transferase activity, transferring phosphorus-containing groups 955
          kinase activity 806
            protein kinase activity 596
              protein serine/threonine kinase activity 429
                G protein-coupled receptor kinase activity 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.