ONTOLOGY REPORT - ANNOTATIONS


Term:transmembrane receptor protein tyrosine kinase activity
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Accession:GO:0004714 term browser browse the term
Definition:Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
Synonyms:exact_synonym: ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity;   receptor protein tyrosine kinase activity
 narrow_synonym: Drosophila Eph kinase activity;   anaplastic lymphoma kinase activity;   ephrin-B3 receptor tyrosine kinase activity;   insulin receptor protein-tyrosine kinase activity;   neurite outgrowth regulating kinase activity;   novel oncogene with kinase-domain activity
 broad_synonym: ATP:protein-tyrosine O-phosphotransferase activity
 related_synonym: neurotrophin TRK receptor activity;   neurotrophin TRKA receptor activity;   neurotrophin TRKB receptor activity;   neurotrophin TRKC receptor activity;   sevenless receptor activity
 xref: EC:2.7.10.1;   MetaCyc:2.7.10.1-RXN;   reactome:R-HSA-166544 "TrkA receptor autophosphorylates";   reactome:R-HSA-167019 "SHC, complexed with TrkA, is tyrosine-phosphorylated";   reactome:R-HSA-167683 "TrkA phosphorylates PLCG1";   reactome:R-HSA-169905 "ARMS is phosphorylated by active TrkA receptor";   reactome:R-HSA-177933 "SHC1 phosphorylation by phosphorylated EGFR";   reactome:R-HSA-198295 "TRKA phosphorylates IRS";   reactome:R-HSA-6784324 "p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA";   reactome:R-HSA-74711 "Phosphorylation of IRS";   reactome:R-HSA-74715 "Autophosphorylation of insulin receptor";   reactome:R-HSA-74742 "Phosphorylation of SHC1";   reactome:R-HSA-8852552 "MST1R autophosphorylates";   reactome:R-HSA-8853792 "RET tyrosine phosphorylation";   reactome:R-HSA-8950269 "STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor";   reactome:R-HSA-8950340 "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation";   reactome:R-HSA-8950354 "STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction";   reactome:R-HSA-8950364 "IL23R in IL23:IL23 receptor complex is phosphorylated";   reactome:R-HSA-8950405 "JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated";   reactome:R-HSA-8950423 "JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated";   reactome:R-HSA-8950453 "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4";   reactome:R-HSA-8950485 "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction";   reactome:R-HSA-8950537 "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated";   reactome:R-HSA-8950591 "JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated";   reactome:R-HSA-8950757 "IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated";   reactome:R-HSA-8982163 "IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3";   reactome:R-HSA-8983300 "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1";   reactome:R-HSA-8983309 "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1";   reactome:R-HSA-8983371 "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5";   reactome:R-HSA-8983424 "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2";   reactome:R-HSA-8986985 "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5";   reactome:R-HSA-8986994 "IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2";   reactome:R-HSA-8986995 "IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA";   reactome:R-HSA-8987012 "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1";   reactome:R-HSA-8987040 "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1";   reactome:R-HSA-8987042 "IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2";   reactome:R-HSA-8987070 "IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3";   reactome:R-HSA-8987084 "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1";   reactome:R-HSA-8987096 "IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3";   reactome:R-HSA-8987129 "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated";   reactome:R-HSA-8987141 "IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3";   reactome:R-HSA-8987150 "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3";   reactome:R-HSA-8987179 "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3";   reactome:R-HSA-8987202 "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2";   reactome:R-HSA-8987255 "IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3"


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transmembrane receptor protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alk ALK receptor tyrosine kinase JBrowse link 6 22,696,415 23,203,791 RGD:1624291
RGD:13792537
G Axl Axl receptor tyrosine kinase JBrowse link 1 82,550,892 82,580,761 RGD:13792537
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:1624291
RGD:13792537
RGD:1600115
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:13792537
G Ddr2 discoidin domain receptor tyrosine kinase 2 JBrowse link 13 88,311,639 88,436,561 RGD:1624291
RGD:13792537
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:13792537
G Epha1 Eph receptor A1 JBrowse link 4 71,749,100 71,763,681 RGD:13792537
G Epha10 EPH receptor A10 JBrowse link 5 142,875,171 142,910,537 RGD:13792537
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
RGD:13792537
G Epha3 Eph receptor A3 JBrowse link 11 421,253 783,037 RGD:13792537
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:13792537
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:13792537
G Epha6 Eph receptor A6 JBrowse link 11 41,867,607 42,843,800 RGD:13792537
G Epha7 Eph receptor A7 JBrowse link 5 43,602,744 43,761,198 RGD:13792537
G Epha8 Eph receptor A8 JBrowse link 5 155,293,731 155,321,016 RGD:13792537
G Ephb1 Eph receptor B1 JBrowse link 8 110,376,954 110,813,193 RGD:13792537
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:13792537
G Ephb3 Eph receptor B3 JBrowse link 11 83,527,960 83,546,742 RGD:13792537
G Ephb4 EPH receptor B4 JBrowse link 12 22,393,338 22,418,332 RGD:1624291
RGD:13792537
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:13792537
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1624291
RGD:13792537
RGD:1600115
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:68774
RGD:13792537
RGD:1600115
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:13792537
RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:13792537
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:13792537
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:13792537
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:13792537
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1626619
RGD:13792537
G Flt3 fms-related tyrosine kinase 3 JBrowse link 12 9,360,439 9,437,004 RGD:13792537
G Flt4 fms-related tyrosine kinase 4 JBrowse link 10 35,078,782 35,120,296 RGD:1624291
RGD:13792537
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:13792537
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1600115
RGD:13792537
G Insrr insulin receptor-related receptor JBrowse link 2 187,161,817 187,181,400 RGD:1624291
RGD:13792537
RGD:1600115
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:13792537
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:1624291
RGD:13792537
G Lmtk2 lemur tyrosine kinase 2 JBrowse link 12 12,409,876 12,546,111 RGD:13792537
G LOC102552659 receptor tyrosine-protein kinase erbB-2-like JBrowse link 10 84,839,053 84,845,803 RGD:1600115
G Ltk leukocyte receptor tyrosine kinase JBrowse link 3 111,553,679 111,560,556 RGD:13792537
G Mertk MER proto-oncogene, tyrosine kinase JBrowse link 3 121,235,230 121,340,932 RGD:1299193
RGD:13792537
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:13792537
RGD:1600115
G Mst1r macrophage stimulating 1 receptor JBrowse link 8 116,686,601 116,700,132 RGD:13792537
G Musk muscle associated receptor tyrosine kinase JBrowse link 5 75,392,790 75,498,694 RGD:13792537
RGD:1600115
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:1600115
RGD:13792537
RGD:1624291
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:1626134
RGD:13792537
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:13792537
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:1624291
RGD:13792537
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:13792537
G Ptk7 protein tyrosine kinase 7 JBrowse link 9 16,662,588 16,729,888 RGD:1624291
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:1624291
RGD:13792537
G Ror1 receptor tyrosine kinase-like orphan receptor 1 JBrowse link 5 118,892,874 119,239,528 RGD:13792537
G Ror2 receptor tyrosine kinase-like orphan receptor 2 JBrowse link 17 11,953,552 12,134,386 RGD:13792537
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase JBrowse link 20 33,100,190 33,323,544 RGD:13792537
G Ryk receptor-like tyrosine kinase JBrowse link 8 111,326,339 111,398,640 RGD:13792537
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:13792537
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 JBrowse link 5 137,294,544 137,321,116 RGD:13792537
G Tyro3 TYRO3 protein tyrosine kinase JBrowse link 3 111,597,102 111,616,142 RGD:13792537
RGD:1600115
brain-derived neurotrophic factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:8554777
RGD:8554094
RGD:1600115
RGD:1624291
RGD:13792537
ephrin receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epha3 Eph receptor A3 JBrowse link 11 421,253 783,037 RGD:1624291
RGD:1600115
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:8554330
RGD:1600115
G Epha7 Eph receptor A7 JBrowse link 5 43,602,744 43,761,198 RGD:70732
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:1624291
G Ephb3 Eph receptor B3 JBrowse link 11 83,527,960 83,546,742 RGD:1624291
G Ephb4 EPH receptor B4 JBrowse link 12 22,393,338 22,418,332 RGD:1624291
epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Efemp1 EGF containing fibulin extracellular matrix protein 1 JBrowse link 14 113,202,382 113,294,993 RGD:1600115
RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:625656
RGD:13792537
RGD:1624291
RGD:1581908
RGD:70386
G Nrg2 neuregulin 2 JBrowse link 18 28,835,391 29,015,552 RGD:1304015
fibroblast growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:728839
RGD:13792537
RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:632663
RGD:13792537
RGD:1624291
RGD:6480435
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:632790
RGD:13792537
RGD:1624291
RGD:1304345
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291
RGD:13792537
G Fgfrl1 fibroblast growth factor receptor-like 1 JBrowse link 14 2,020,110 2,032,169 RGD:1624291
RGD:13792537
GPI-linked ephrin receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epha3 Eph receptor A3 JBrowse link 11 421,253 783,037 RGD:1600115
RGD:1624291
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:1600115
RGD:1624291
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:1600115
RGD:1624291
G Epha7 Eph receptor A7 JBrowse link 5 43,602,744 43,761,198 RGD:1624291
RGD:1600115
G Epha8 Eph receptor A8 JBrowse link 5 155,293,731 155,321,016 RGD:1600115
RGD:1624291
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:8553786
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:8553786
hepatocyte growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:2317458
RGD:13792537
RGD:1624291
insulin-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:13792537
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1580595
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2293184
RGD:1600765
RGD:1299201
G Insrr insulin receptor-related receptor JBrowse link 2 187,161,817 187,181,400 RGD:13792537
G LOC259246 alpha-2u globulin PGCL1 RGD:1600115
insulin-like growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:70266
RGD:1600115
RGD:1624291
RGD:12904886
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:1298967
macrophage colony-stimulating factor receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:1600115
RGD:13792537
RGD:1624291
placental growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1600115
RGD:1624291
platelet-derived growth factor alpha-receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:729439
RGD:13792537
RGD:1600115
RGD:1624291
platelet-derived growth factor beta-receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1600115
RGD:13792537
RGD:1624291
platelet-derived growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:628442
RGD:13792537
RGD:1581762
RGD:633648
protein tyrosine kinase collagen receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:1600115
RGD:13792537
RGD:1624291
G Ddr2 discoidin domain receptor tyrosine kinase 2 JBrowse link 13 88,311,639 88,436,561 RGD:1624291
RGD:13792537
stem cell factor receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:1624291
RGD:1600115
transmembrane-ephrin receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epha1 Eph receptor A1 JBrowse link 4 71,749,100 71,763,681 RGD:1624291
RGD:13792537
G Epha10 EPH receptor A10 JBrowse link 5 142,875,171 142,910,537 RGD:1624291
RGD:13792537
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:13792537
G Epha3 Eph receptor A3 JBrowse link 11 421,253 783,037 RGD:13792537
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:1624291
RGD:13792537
RGD:1600115
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:13792537
G Epha6 Eph receptor A6 JBrowse link 11 41,867,607 42,843,800 RGD:13792537
G Epha7 Eph receptor A7 JBrowse link 5 43,602,744 43,761,198 RGD:13792537
G Epha8 Eph receptor A8 JBrowse link 5 155,293,731 155,321,016 RGD:13792537
G Ephb1 Eph receptor B1 JBrowse link 8 110,376,954 110,813,193 RGD:1624291
RGD:13792537
RGD:1600115
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:1624291
RGD:13792537
G Ephb3 Eph receptor B3 JBrowse link 11 83,527,960 83,546,742 RGD:13792537
G Ephb4 EPH receptor B4 JBrowse link 12 22,393,338 22,418,332 RGD:13792537
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:13792537
vascular endothelial growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1626621
RGD:13792537
RGD:1624291
G Flt4 fms-related tyrosine kinase 4 JBrowse link 10 35,078,782 35,120,296 RGD:727326
RGD:13792537
RGD:1624291
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:729081
RGD:1600115
RGD:13792537
RGD:1624291
RGD:1626621
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
RGD:1600115
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1600115
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:1624291
RGD:1600115
VEGF-A-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1600115
RGD:1624291
VEGF-B-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1600115
RGD:1624291
VEGF-C-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt4 fms-related tyrosine kinase 4 JBrowse link 10 35,078,782 35,120,296 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18247
    catalytic activity 5761
      catalytic activity, acting on a protein 2193
        protein kinase activity 609
          transmembrane receptor protein kinase activity 81
            transmembrane receptor protein tyrosine kinase activity 63
              boss receptor activity 0
              brain-derived neurotrophic factor-activated receptor activity 1
              ephrin receptor activity + 16
              epidermal growth factor-activated receptor activity + 3
              fibroblast growth factor-activated receptor activity 5
              hepatocyte growth factor-activated receptor activity 1
              insulin-activated receptor activity 4
              insulin-like growth factor-activated receptor activity 2
              macrophage colony-stimulating factor receptor activity 1
              placental growth factor-activated receptor activity 1
              platelet-derived growth factor-activated receptor activity + 2
              protein tyrosine kinase collagen receptor activity 2
              stem cell factor receptor activity 1
              vascular endothelial growth factor-activated receptor activity + 6
Path 2
Term Annotations click to browse term
  molecular_function 18247
    catalytic activity 5761
      transferase activity 2274
        transferase activity, transferring phosphorus-containing groups 956
          kinase activity 807
            protein kinase activity 609
              protein tyrosine kinase activity 124
                transmembrane receptor protein tyrosine kinase activity 63
                  boss receptor activity 0
                  brain-derived neurotrophic factor-activated receptor activity 1
                  ephrin receptor activity + 16
                  epidermal growth factor-activated receptor activity + 3
                  fibroblast growth factor-activated receptor activity 5
                  hepatocyte growth factor-activated receptor activity 1
                  insulin-activated receptor activity 4
                  insulin-like growth factor-activated receptor activity 2
                  macrophage colony-stimulating factor receptor activity 1
                  placental growth factor-activated receptor activity 1
                  platelet-derived growth factor-activated receptor activity + 2
                  protein tyrosine kinase collagen receptor activity 2
                  stem cell factor receptor activity 1
                  vascular endothelial growth factor-activated receptor activity + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.