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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium-dependent protein serine/threonine phosphatase activity
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Accession:GO:0004723 term browser browse the term
Definition:Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.
Synonyms:exact_synonym: calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity
 narrow_synonym: calcineurin
 alt_id: GO:0008596
 xref: reactome:R-HSA-2025882 "Calcineurin dephosphorylates NFATC1,2,3"


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calcium-dependent protein serine/threonine phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta JBrowse link 14 1,469,748 1,476,353 RGD:1624291
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:729536
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:729536
calmodulin-dependent protein phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A JBrowse link 6 94,433,658 94,484,979 RGD:1600115
RGD:1624291
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F JBrowse link 11 88,313,709 88,343,726 RGD:1600115
RGD:1624291
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:1600115
RGD:13792537
RGD:1624291
RGD:13507300
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1600115
RGD:13792537
RGD:1624291
G Ppp3cc protein phosphatase 3 catalytic subunit gamma JBrowse link 15 51,896,427 51,968,075 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19490
    catalytic activity 6049
      catalytic activity, acting on a protein 2288
        phosphoprotein phosphatase activity 177
          protein serine/threonine phosphatase activity 64
            calcium-dependent protein serine/threonine phosphatase activity 6
              calmodulin-dependent protein phosphatase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 19490
    catalytic activity 6049
      hydrolase activity 2605
        hydrolase activity, acting on ester bonds 782
          phosphoric ester hydrolase activity 375
            phosphatase activity 279
              phosphoprotein phosphatase activity 177
                protein serine/threonine phosphatase activity 64
                  calcium-dependent protein serine/threonine phosphatase activity 6
                    calmodulin-dependent protein phosphatase activity 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.