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Term:sterol esterase activity
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Accession:GO:0004771 term browser browse the term
Definition:Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid.
Synonyms:exact_synonym: acylcholesterol lipase activity;   cholesterase activity;   cholesterol ester hydrolase activity;   cholesteryl ester hydrolase activity;   cholesteryl ester synthase activity;   cholesteryl esterase activity;   sterol ester hydrolase activity;   steryl-ester acylhydrolase activity;   triterpenol esterase activity
 narrow_synonym: cholesterol ester synthase activity;   cholesterol esterase activity
 xref: EC:;   MetaCyc:STEROL-ESTERASE-RXN;   reactome:R-HSA-192417 "Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)";   reactome:R-HSA-6813720 "NCEH1 hydrolyzes cholesterol esters";   reactome:R-HSA-8865667 "LIPA hydrolyses sterol esters to sterols and fatty acids"

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sterol esterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:728247
G Ces1a carboxylesterase 1A JBrowse link 19 15,339,152 15,366,079 RGD:13792537
G Ces1c carboxylesterase 1C JBrowse link 19 15,294,524 15,335,005 RGD:13792537
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:1600115
G Ces1e carboxylesterase 1E RGD:13792537
G Ces1f carboxylesterase 1F JBrowse link 19 15,081,117 15,126,629 RGD:13792537
G Ces4a carboxylesterase 4A JBrowse link 19 37,090,018 37,111,448 RGD:13792537
G Ces5a carboxylesterase 5A JBrowse link 19 12,097,529 12,136,579 RGD:13792537
G Cesl1 carboxylesterase-like 1 RGD:13792537
G Lipa lipase A, lysosomal acid type JBrowse link 1 252,816,536 252,959,348 RGD:1626385
G Lipo1 lipase, member O1 JBrowse link 1 252,102,233 252,117,030 RGD:13792537

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  molecular_function 19678
    catalytic activity 6023
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 790
          carboxylic ester hydrolase activity 163
            sterol esterase activity 11
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.