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Term:tryptophan 2,3-dioxygenase activity
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Accession:GO:0004833 term browser browse the term
Definition:Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.
Synonyms:exact_synonym: L-tryptophan 2,3-dioxygenase activity;   L-tryptophan pyrrolase activity;   L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing);   indoleamine-pyrrole 2,3-dioxygenase activity;   tryptamin 2,3-dioxygenase activity;   tryptamine 2,3-dioxygenase activity
 broad_synonym: indolamine 2,3-dioxygenase activity;   tryptophan oxygenase activity;   tryptophan peroxidase activity;   tryptophan pyrrolase activity
 related_synonym: TDO
 alt_id: GO:0004426
 xref: EC:;   MetaCyc:TRYPTOPHAN-23-DIOXYGENASE-RXN;   RHEA:24536;   reactome:R-HSA-198563 "IDO1 dioxygenates L-Trp to NFK";   reactome:R-HSA-71188 "TDO tetramer dioxygenates L-Trp to NFK";   reactome:R-HSA-888614 "IDO2 dioxygenates L-Trp to NFK"

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  molecular_function 324
    catalytic activity 81
      oxidoreductase activity 7
        dioxygenase activity 0
          oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0
            tryptophan 2,3-dioxygenase activity 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.