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ONTOLOGY REPORT - ANNOTATIONS


Term:GABA-A receptor activity
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Accession:GO:0004890 term browser browse the term
Definition:Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'chloride channel activity ; GO:0005254' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'.
Synonyms:exact_synonym: ionotropic GABA receptor activity


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GABA-A receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gabra3 gamma-aminobutyric acid type A receptor alpha3 subunit JBrowse link NW_004936714 461,050 675,745 RGD:9068941
G Gabra5 gamma-aminobutyric acid type A receptor alpha5 subunit JBrowse link NW_004936471 39,781,451 39,856,766 RGD:9068941
G Gabra6 gamma-aminobutyric acid type A receptor alpha6 subunit JBrowse link NW_004936515 1,982,415 1,997,740 RGD:9068941
G Gabrb1 gamma-aminobutyric acid type A receptor beta1 subunit JBrowse link NW_004936482 13,219,962 13,593,868 RGD:9068941
G Gabrb2 gamma-aminobutyric acid type A receptor beta2 subunit JBrowse link NW_004936515 2,127,107 2,359,697 RGD:9068941
G Gabrb3 gamma-aminobutyric acid type A receptor beta3 subunit JBrowse link NW_004936471 39,791,633 40,193,049 RGD:9068941
G Gabrd gamma-aminobutyric acid type A receptor delta subunit JBrowse link NW_004936737 1,400,437 1,405,885 RGD:9068941
G Gabre gamma-aminobutyric acid type A receptor epsilon subunit JBrowse link NW_004936714 808,287 827,990 RGD:9068941
G Gabrg1 gamma-aminobutyric acid type A receptor gamma1 subunit JBrowse link NW_004936482 12,390,328 12,473,904 RGD:9068941
G Gabrg2 gamma-aminobutyric acid type A receptor gamma2 subunit JBrowse link NW_004936515 1,609,370 1,670,412 RGD:9068941
G Gabrg3 gamma-aminobutyric acid type A receptor gamma3 subunit JBrowse link NW_004936471 39,184,683 39,256,439 RGD:9068941
G Gabrp gamma-aminobutyric acid type A receptor pi subunit JBrowse link NW_004936609 4,100,562 4,122,569 RGD:9068941
G Gabrr2 gamma-aminobutyric acid type A receptor rho2 subunit JBrowse link NW_004936510 2,891,136 2,949,428 RGD:9068941

Term paths to the root
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Term Annotations click to browse term
  molecular_function 13925
    molecular transducer activity 566
      signaling receptor activity 566
        transmembrane signaling receptor activity 473
          GABA receptor activity 18
            GABA-A receptor activity 13
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.