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ONTOLOGY REPORT - ANNOTATIONS


Term:osmosensor activity
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Accession:GO:0005034 term browser browse the term
Definition:Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.


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osmosensor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO MGI:MGI:2667379 (MGI:MGI:1926591|PMID:11025659), (MGI:MGI:2667243|PMID:12777254) RGD PMID:11025659, PMID:12777254 MGI:MGI:1926591, MGI:MGI:2667243 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
osmolarity-sensing cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem63a transmembrane protein 63a ISO (MGI:MGI:6378787|PMID:27045885) RGD PMID:27045885 MGI:MGI:6378787 NCBI chr13:99,219,585...99,253,176
Ensembl chr13:99,220,510...99,253,316
JBrowse link
G Tmem63b transmembrane protein 63B ISO (MGI:MGI:6378298|PMID:31243992), (MGI:MGI:6378787|PMID:27045885) RGD PMID:27045885, PMID:31243992 MGI:MGI:6378298, MGI:MGI:6378787 NCBI chr 9:17,698,697...17,725,479
Ensembl chr 9:17,705,212...17,725,378
JBrowse link
G Tmem63c transmembrane protein 63c ISS
ISO
GO_REF:0000024
(MGI:MGI:6378787|PMID:27045885)
UniProt
RGD
PMID:27045885 GO_REF:0000024, MGI:MGI:6378787 NCBI chr 6:111,044,099...111,120,659
Ensembl chr 6:111,049,559...111,120,799
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:18279313 RGD:10047048 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    small molecule sensor activity 10
      osmosensor activity 5
        osmolarity-sensing cation channel activity 4
Path 2
Term Annotations click to browse term
  molecular_function 20457
    molecular transducer activity 2656
      signaling receptor activity 2656
        transmembrane signaling receptor activity 2499
          osmosensor activity 5
            osmolarity-sensing cation channel activity 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.