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ONTOLOGY REPORT - ANNOTATIONS


Term:death receptor activity
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Accession:GO:0005035 term browser browse the term
Definition:Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.
Synonyms:related_synonym: apoptosis-activating receptor activity


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death receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngfr nerve growth factor receptor ISO
IEA
IBA
(MGI:MGI:1859527|PMID:10764727)
GO_REF:0000107
UniProtKB:P01138:PRO_0000019600|UniProtKB:P05067:PRO_0000000092 (PMID:11927634)
PMID:21873635
RGD
Ensembl
PMID:10764727, PMID:11927634, PMID:21873635 GO_REF:0000107, MGI:MGI:1859527, RGD:13792537 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nradd neurotrophin receptor associated death domain IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:118,890,402...118,893,712
Ensembl chr 8:118,890,399...118,893,702
JBrowse link
tumor necrosis factor-activated receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:16154149, PMID:21873635 RGD:1582433, RGD:13792537 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A ISO
IBA
(MGI:MGI:4413614|PMID:19940926)
PMID:21873635
RGD PMID:19940926, PMID:21873635 MGI:MGI:4413614, RGD:13792537 NCBI chr13:25,778,306...25,835,802
Ensembl chr13:25,778,317...25,835,957
JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:173,459,371...173,463,980
Ensembl chr 5:173,460,354...173,463,140
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IMP
IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
MGI:MGI:1861040|UniProtKB:P01374|UniProtKB:P06804 (MGI:MGI:2152007|PMID:11588035), (MGI:MGI:59648|PMID:1645445)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:1645445, PMID:11588035, PMID:20649583, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2152007, MGI:MGI:59648, RGD:5130976, RGD:13792537 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IDA
IBA
ISO
PMID:21873635
UniProtKB:P01374|UniProtKB:P06804 (MGI:MGI:59648|PMID:1645445)
RGD PMID:1645445, PMID:12376316, PMID:21873635 MGI:MGI:59648, RGD:628388, RGD:13792537 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 TAS
IBA
ISO
PMID:21873635
UniProtKB:P43488 (MGI:MGI:2683815|PMID:14635034)
RGD PMID:14635034, PMID:2157591, PMID:21873635 MGI:MGI:2683815, RGD:70044, RGD:13792537 NCBI chr 5:173,447,784...173,450,474
Ensembl chr 5:173,447,784...173,450,474
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    molecular transducer activity 2656
      signaling receptor activity 2656
        transmembrane signaling receptor activity 2499
          death receptor activity 8
            TRAIL receptor activity 0
            tumor necrosis factor-activated receptor activity + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.