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ONTOLOGY REPORT - ANNOTATIONS


Term:delayed rectifier potassium channel activity
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Accession:GO:0005251 term browser browse the term
Definition:Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
Synonyms:xref: reactome:R-HSA-5577050 "AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region";   reactome:R-HSA-5577237 "KCNH2:KCNE transport K+ from cytosol to extracellular region"


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delayed rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC125757.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 5:2,980,046...2,982,603 JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 IMP
ISO
IBA
ISS
IDA
(MGI:5605952|PMID:15361858)
PMID:21873635
GO_REF:0000024
(PMID:19912772)
PMID:8038169
PMID:22206926
RGD
UniProt
PMID:15361858, PMID:19912772, PMID:14602579, PMID:21873635, PMID:8038169, PMID:22206926 GO_REF:0000024, MGI:5605952, RGD:1300201, RGD:13792537, RGD:10047389, RGD:10047237 NCBI chr 4:159,190,781...159,192,526
Ensembl chr 4:159,190,804...159,192,526
JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:209,920,590...209,932,665
Ensembl chr 2:209,920,590...209,932,665
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 IMP
IBA
PMID:19713757
PMID:21873635
UniProt
GO_Central
PMID:19713757, PMID:21873635 RGD:10047171, RGD:13792537 NCBI chr 2:209,838,607...209,852,471
Ensembl chr 2:209,838,869...209,852,471
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:14602579, PMID:21873635 RGD:1300201, RGD:13792537 NCBI chr 2:209,766,767...209,768,344
Ensembl chr 2:209,766,512...209,769,711
JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:98,293,295...98,300,763
Ensembl chr 3:98,297,554...98,300,680
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IDA
IBA
ISO
ISS
PMID:15618540
PMID:21873635
(PMID:12130714), (PMID:19343045), (PMID:1986382)
GO_REF:0000024
RGD
UniProt
PMID:1986382, PMID:12130714, PMID:19343045, PMID:15618540, PMID:21873635 GO_REF:0000024, RGD:10047274, RGD:13792537 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcna6 potassium voltage-gated channel subfamily A member 6 IDA
IBA
ISO
IEA
PMID:15618540
PMID:21873635
(PMID:2347305)
GO_REF:0000107
RGD
Ensembl
PMID:2347305, PMID:15618540, PMID:21873635 GO_REF:0000107, RGD:10047274, RGD:13792537 NCBI chr 4:159,253,934...159,287,193
Ensembl chr 4:159,253,934...159,287,193
JBrowse link
G Kcna7 potassium voltage-gated channel subfamily A member 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:101,397,828...101,403,320
Ensembl chr 1:101,397,828...101,403,320
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 IDA
ISO
IBA
IEA
IMP
(MGI:3770494|PMID:17767909), (MGI:5508719|PMID:22056818), (MGI:5634878|PMID:24494598)
PMID:21873635
(PMID:19074135), (PMID:19223394)
GO_REF:0000107
PMID:8980147
PMID:20202934
PMID:19690160
PMID:19077057
PMID:12954870
PMID:9305895
PMID:19219384
RGD
Ensembl
PMID:17767909, PMID:19074135, PMID:19223394, PMID:22056818, PMID:24494598, PMID:8189205, PMID:21873635, PMID:8980147, PMID:20202934, PMID:19690160, PMID:19077057, PMID:12954870, PMID:9305895, PMID:19219384, PMID:9545040 GO_REF:0000107, MGI:3770494, MGI:5508719, MGI:5634878, RGD:2303541, RGD:13792537, RGD:10047188, RGD:10047337, RGD:10047295, RGD:10047372, RGD:10047250, RGD:737625, RGD:7243947, RGD:2303542 NCBI chr 3:163,850,785...163,935,610
Ensembl chr 3:163,850,785...163,935,617
JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 IDA
IBA
PMID:9305895
PMID:21873635
PMID:20202934
UniProt
GO_Central
PMID:9305895, PMID:21873635, PMID:20202934 RGD:737625, RGD:13792537, RGD:10047337 NCBI chr 5:2,975,934...3,430,837 JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IDA
IBA
PMID:12954870
PMID:21873635
UniProt
GO_Central
PMID:12954870, PMID:21873635 RGD:10047250, RGD:13792537 NCBI chr 1:102,414,352...102,456,718
Ensembl chr 1:102,414,625...102,456,411
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 IDA
IBA
PMID:10482766
PMID:21873635
PMID:11281123
PMID:7643197
UniProt
GO_Central
PMID:10482766, PMID:21873635, PMID:11281123, PMID:7643197 RGD:9685780, RGD:13792537, RGD:10047322, RGD:9686052 NCBI chr 7:54,978,453...55,159,362
Ensembl chr 7:54,980,120...55,159,351
JBrowse link
G Kcnc3 potassium voltage-gated channel subfamily C member 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,593,453...100,607,874
Ensembl chr 1:100,593,680...100,607,874
JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 contributes_to IMP
ISO
ISS
(PMID:10400998), (PMID:11299204), (PMID:12522251), (PMID:19646991), (PMID:8900283), (PMID:9354802)
GO_REF:0000024
(PMID:24269949)
RGD
UniProt
PMID:8900283, PMID:9354802, PMID:10400998, PMID:11299204, PMID:12522251, PMID:19646991, PMID:24269949, PMID:11810210 GO_REF:0000024, RGD:729219 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 contributes_to ISO
IBA
IDA
(PMID:10219239)
PMID:21873635
RGD PMID:10219239, PMID:21873635, PMID:10219239 RGD:13792537, RGD:633041 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 contributes_to IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 contributes_to IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:84,688,873...84,693,066
Ensembl chr 9:84,689,150...84,690,338
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 contributes_to IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:113,583,844...113,584,459
Ensembl chr  X:113,583,844...113,584,459
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 IDA
IBA
ISO
PMID:8980147
PMID:21873635
(PMID:19074135)
RGD PMID:19074135, PMID:8980147, PMID:21873635 RGD:10047188, RGD:13792537 NCBI chr 3:165,020,230...165,040,966
Ensembl chr 3:165,020,230...165,039,707
JBrowse link
G Kcng3 potassium voltage-gated channel modifier subfamily G member 3 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:19074135)
Ensembl
UniProt
RGD
PMID:19074135, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 6:6,794,808...6,842,758
Ensembl chr 6:6,794,808...6,842,758
JBrowse link
G Kcng4 potassium voltage-gated channel modifier subfamily G member 4 ISO
IBA
(PMID:19074135)
PMID:21873635
RGD PMID:19074135, PMID:21873635 RGD:13792537 NCBI chr19:52,270,907...52,283,317
Ensembl chr19:52,270,927...52,282,877
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 IDA
ISO
ISS
PMID:27516594
(MGI:5616314|PMID:19671703)
(PMID:22732247), (PMID:27005320), (PMID:27325704)
GO_REF:0000024
RGD
UniProt
PMID:19671703, PMID:22732247, PMID:27005320, PMID:27325704, PMID:27516594 GO_REF:0000024, MGI:5616314, RGD:11533419 NCBI chr13:110,920,712...111,232,291
Ensembl chr13:110,920,737...111,232,269
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 IEA
ISO
GO_REF:0000107
UniProtKB:Q6ZRF8 (PMID:25281747), (PMID:7736582)
Ensembl
RGD
PMID:7736582, PMID:25281747 GO_REF:0000107 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 contributes_to IDA
IBA
ISO
IEA
PMID:11220365
PMID:21873635
(PMID:12522251), (PMID:24184248), (PMID:24269949), (PMID:25037568)
(PMID:10400998), (PMID:11299204), (PMID:19646991), (PMID:8900283), (PMID:9354802)
GO_REF:0000107
RGD
Ensembl
PMID:8900283, PMID:9354802, PMID:10400998, PMID:11299204, PMID:12522251, PMID:19646991, PMID:24184248, PMID:24269949, PMID:25037568, PMID:11220365, PMID:21873635 GO_REF:0000107, RGD:633100, RGD:13792537 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:176,585,897...176,645,029
Ensembl chr 3:176,589,906...176,644,951
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:106,714,479...107,009,639
Ensembl chr 7:106,717,229...107,009,330
JBrowse link
G Kcnq5 potassium voltage-gated channel subfamily Q member 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:27,565,869...28,141,114
Ensembl chr 9:27,562,959...27,761,733
JBrowse link
G Kcns1 potassium voltage-gated channel, modifier subfamily S, member 1 ISO
IBA
ISS
(PMID:10484328)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:10484328, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:160,554,423...160,561,820
Ensembl chr 3:160,554,425...160,561,741
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    transporter activity 1204
      transmembrane transporter activity 1114
        ion transmembrane transporter activity 973
          voltage-gated ion channel activity 196
            voltage-gated cation channel activity 146
              voltage-gated potassium channel activity 90
                delayed rectifier potassium channel activity 30
Path 2
Term Annotations click to browse term
  molecular_function 20457
    transporter activity 1204
      transmembrane transporter activity 1114
        passive transmembrane transporter activity 494
          channel activity 494
            gated channel activity 342
              voltage-gated channel activity 197
                voltage-gated ion channel activity 196
                  voltage-gated cation channel activity 146
                    voltage-gated potassium channel activity 90
                      delayed rectifier potassium channel activity 30
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.