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ONTOLOGY REPORT - ANNOTATIONS


Term:protein binding
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Accession:GO:0005515 term browser browse the term
Definition:Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
Synonyms:exact_synonym: protein amino acid binding
 narrow_synonym: glycoprotein binding
 alt_id: GO:0001948;   GO:0045308
 xref: MIPS_funcat:16.01;   MIPS_funcat:18.01.07;   reactome:R-HSA-170835 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3";   reactome:R-HSA-170846 "TGFBR2 recruits TGFBR1"


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  molecular_function 19460
    binding 15841
      protein binding 12616
        14-3-3 protein binding 33
        ATP-dependent protein binding 11
        CNBH domain intrinsic ligand binding 0
        FBXO family protein binding 2
        G-protein alpha-subunit binding 41
        G-protein beta-subunit binding 25
        G-protein gamma-subunit binding 2
        GDP-dissociation inhibitor binding + 8
        GTP-dependent protein binding 23
        GTPase activating protein binding 20
        MDM2/MDM4 family protein binding 10
        RBL family protein binding 0
        RHG protein domain binding 0
        S100 protein binding 15
        SMAD binding + 80
        SMC family protein binding 0
        SNAP receptor activity 33
        SNARE binding + 123
        SOCS family protein binding 0
        STAT family protein binding 8
        TAP binding + 5
        TIMP family protein binding 0
        TRAIL binding 1
        Wnt-protein binding 36
        X11-like protein binding 1
        adiponectin binding 3
        alpha-catenin binding 13
        angiostatin binding 4
        antisigma factor binding 0
        apolipoprotein binding + 18
        arrestin family protein binding 9
        basal transcription machinery binding + 60
        beta-2-microglobulin binding 6
        beta-catenin binding 89
        bone sialoprotein binding 2
        calcium-dependent protein binding + 76
        calmodulin binding 174
        cell adhesion molecule binding + 245
        cell-cell adhesion mediator activity + 29
        chaperone binding 109
        clathrin binding + 54
        co-receptor binding 13
        complement binding + 25
        connexin binding 7
        copper-dependent protein binding 3
        cullin family protein binding 19
        cyclin binding 30
        cytokine binding + 139
        cytoskeletal protein binding + 1014
        delta-catenin binding 9
        denatured protein binding 2
        dynein heavy chain binding 14
        dynein intermediate chain binding 32
        dynein light chain binding 13
        dynein light intermediate chain binding 30
        dystroglycan binding 11
        endocytic targeting sequence binding 0
        enzyme binding + 2384
        extracellular matrix protein binding 8
        farnesylated protein binding 1
        fibronectin binding 33
        gamma-catenin binding 13
        glycosylated region protein binding 0
        growth factor binding + 150
        haptoglobin binding 11
        heat shock protein binding + 147
        hedgehog family protein binding 4
        hemoglobin binding + 12
        hexon binding 0
        histone binding + 227
        identical protein binding + 2028
        importin-alpha family protein binding 8
        inhibin binding 7
        insulin binding 7
        insulin receptor substrate binding 11
        ion channel binding 148
        kininogen binding + 4
        lamin binding 18
        laminin binding + 33
        misfolded protein binding 29
        modification-dependent protein binding + 173
        nodal binding 4
        opsin binding 5
        opsonin binding + 17
        p53 binding 72
        phosphatidylinositol 3-kinase binding + 38
        phosphoprotein binding + 102
        phytochrome binding 0
        poly-glutamine tract binding 0
        preprotein binding 3
        profilin binding 11
        proline-rich region binding + 20
        protein C-terminus binding 235
        protein N-terminus binding + 132
        protein antigen binding 13
        protein binding involved in negative regulation of telomere maintenance via telomerase 0
        protein binding, bridging + 174
        protein dimerization activity + 1295
        protein domain specific binding + 807
        protein kinase A binding + 51
        protein self-association + 70
        proteoglycan binding + 38
        scaffold protein binding 75
        serpin family protein binding 1
        signaling receptor binding + 1684
        splicing factor binding 4
        sterol-dependent protein binding 0
        tapasin binding 2
        toxin-antitoxin pair type II binding 0
        transcription factor binding + 732
        translation elongation factor binding 1
        translation initiation factor binding + 38
        ubiquitin-like protein binding + 99
        unfolded protein binding 106
        very-low-density lipoprotein particle binding 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.