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ONTOLOGY REPORT - ANNOTATIONS


Term:protein binding
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Accession:GO:0005515 term browser browse the term
Definition:Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
Synonyms:exact_synonym: protein amino acid binding
 narrow_synonym: glycoprotein binding
 alt_id: GO:0001948;   GO:0045308
 xref: reactome:R-HSA-170835 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3";   reactome:R-HSA-170846 "TGFBR2 recruits TGFBR1"


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  molecular_function 14671
    binding 13055
      protein binding 10841
        14-3-3 protein binding 31
        ATP-dependent protein binding 8
        CNBH domain intrinsic ligand binding 0
        FBXO family protein binding 2
        G-protein alpha-subunit binding 27
        G-protein beta-subunit binding 19
        G-protein gamma-subunit binding 2
        GDP-dissociation inhibitor binding + 4
        GTP-dependent protein binding 22
        GTPase activating protein binding 14
        MDM2/MDM4 family protein binding 8
        RBL family protein binding 0
        RHG protein domain binding 0
        S100 protein binding 13
        SMAD binding + 76
        SMC family protein binding 1
        SNARE binding + 107
        SOCS family protein binding 0
        STAT family protein binding 7
        TAP binding + 3
        TIMP family protein binding 0
        TRAIL binding 1
        Wnt-protein binding 30
        X11-like protein binding 1
        adiponectin binding 3
        alpha-catenin binding 10
        angiostatin binding 4
        antisigma factor binding 0
        apolipoprotein binding + 18
        arrestin family protein binding 10
        basal transcription machinery binding + 55
        beta-2-microglobulin binding 2
        beta-catenin binding 84
        bone sialoprotein binding 1
        calcium-dependent protein binding + 62
        calmodulin binding 190
        cell adhesion molecule binding + 492
        cell-cell adhesion mediator activity + 48
        chaperone binding 100
        clathrin binding + 58
        co-receptor binding 12
        complement binding + 16
        connexin binding 7
        copper-dependent protein binding 3
        cullin family protein binding 23
        cyclin binding 31
        cytokine binding + 123
        cytoskeletal protein binding + 945
        delta-catenin binding 6
        denatured protein binding 0
        dynein heavy chain binding 14
        dynein intermediate chain binding 30
        dynein light chain binding 10
        dynein light intermediate chain binding 29
        dystroglycan binding 9
        endocytic targeting sequence binding 0
        enzyme binding + 2091
        extracellular matrix protein binding 5
        farnesylated protein binding 1
        fibronectin binding 24
        gamma-catenin binding 12
        glycosylated region protein binding 1
        growth factor binding + 136
        haptoglobin binding 2
        heat shock protein binding + 117
        hedgehog family protein binding 3
        hemoglobin binding + 3
        hexon binding 0
        histone binding + 187
        identical protein binding + 1742
        importin-alpha family protein binding 7
        inhibin binding 5
        insulin binding 6
        insulin receptor substrate binding 11
        ion channel binding 128
        kininogen binding + 2
        lamin binding 16
        laminin binding + 28
        misfolded protein binding 23
        modification-dependent protein binding + 142
        nodal binding 2
        opsin binding 4
        opsonin binding + 12
        p53 binding 67
        phosphatidylinositol 3-kinase binding + 31
        phosphoprotein binding + 84
        phytochrome binding 0
        poly-glutamine tract binding 0
        preprotein binding 1
        profilin binding 11
        proline-rich region binding + 20
        protein C-terminus binding 200
        protein N-terminus binding + 107
        protein antigen binding 5
        protein dimerization activity + 904
        protein domain specific binding + 670
        protein kinase A binding + 48
        protein self-association + 55
        protein-macromolecule adaptor activity + 260
        proteoglycan binding + 32
        scaffold protein binding 56
        serpin family protein binding 0
        signaling receptor binding + 1376
        splicing factor binding 3
        sterol-dependent protein binding 0
        tapasin binding 1
        toxin-antitoxin pair type II binding 0
        transcription factor binding + 654
        translation elongation factor binding 1
        translation initiation factor binding + 31
        ubiquitin-like protein binding + 97
        unfolded protein binding 108
        very-low-density lipoprotein particle binding 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.