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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork
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Accession:GO:0005657 term browser browse the term
Definition:The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
Synonyms:related_synonym: replication focus
 xref: Wikipedia:Replication_fork


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replication fork term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:1624291
G Dmap1 DNA methyltransferase 1-associated protein 1 JBrowse link 5 136,533,791 136,541,795 RGD:1624291
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1624291
RGD:1600115
G Donson DNA replication fork stabilization factor DONSON JBrowse link 11 31,834,608 31,847,751 RGD:1624291
G H2ax H2A.X variant histone JBrowse link 8 48,665,652 48,666,981 RGD:1624291
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:1624291
G Hmces 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 4 119,841,088 119,864,115 RGD:1600115
RGD:1624291
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1600115
RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:1624291
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:13792537
G Polh DNA polymerase eta JBrowse link 9 17,163,354 17,198,006 RGD:13792537
G Primpol primase and DNA directed polymerase JBrowse link 16 48,863,385 48,900,409 RGD:1600115
RGD:1624291
G Rad18 RAD18 E3 ubiquitin protein ligase JBrowse link 4 144,537,329 144,620,606 RGD:1624291
G Rad51b RAD51 paralog B JBrowse link 6 102,473,978 103,018,185 RGD:1624291
RGD:13792537
G Rad51c RAD51 paralog C JBrowse link 10 74,697,713 74,724,004 RGD:1624291
RGD:13792537
G Rad51d RAD51 paralog D JBrowse link 10 70,222,703 70,241,352 RGD:1624291
RGD:13792537
G Radx RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 110,670,037 110,782,420 RGD:1624291
RGD:1600115
G Rtfdc1 replication termination factor 2 domain containing 1 JBrowse link 3 170,443,895 170,473,456 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 JBrowse link 9 10,738,211 10,758,403 RGD:1600115
RGD:1624291
G Wrn WRN RecQ like helicase JBrowse link 16 62,483,773 62,619,018 RGD:1624291
G Xrcc2 X-ray repair cross complementing 2 JBrowse link 4 5,842,013 5,860,516 RGD:1624291
RGD:13792537
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
RGD:13792537
alpha DNA polymerase:primase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pola1 DNA polymerase alpha 1, catalytic subunit JBrowse link X 62,382,604 62,698,830 RGD:1580605
RGD:1624291
RGD:13792537
RGD:1600115
RGD:2307013
G Pola2 DNA polymerase alpha 2, accessory subunit JBrowse link 1 221,297,417 221,321,601 RGD:633584
RGD:1624291
RGD:13792537
RGD:1600115
RGD:2307013
G Prim1 DNA primase subunit 1 JBrowse link 7 2,435,524 2,451,169 RGD:13792537
G Prim2 DNA primase subunit 2 JBrowse link 9 38,535,435 38,745,058 RGD:13792537
delta DNA polymerase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pold1 DNA polymerase delta 1, catalytic subunit JBrowse link 1 100,538,066 100,554,105 RGD:2307013
RGD:1624291
RGD:1600115
RGD:13792537
RGD:729526
G Pold2 DNA polymerase delta 2, accessory subunit JBrowse link 14 86,111,416 86,117,578 RGD:2307013
RGD:1624291
RGD:13792537
RGD:729526
G Pold3 DNA polymerase delta 3, accessory subunit JBrowse link 1 165,085,142 165,122,385 RGD:2307013
RGD:13792537
RGD:1624291
G Pold4 DNA polymerase delta 4, accessory subunit JBrowse link 1 219,480,841 219,483,244 RGD:2307013
RGD:13792537
DNA replication factor A complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcas2 BCAS2, pre-mRNA processing factor JBrowse link 2 205,662,633 205,670,514 RGD:1624291
G Cdc5l cell division cycle 5-like JBrowse link 9 17,949,764 17,988,514 RGD:1624291
RGD:1600115
G Ercc5 ERCC excision repair 5, endonuclease JBrowse link 9 50,928,847 50,970,962 RGD:1624291
G Helb DNA helicase B JBrowse link 7 64,860,641 64,888,146 RGD:1624291
G Plrg1 pleiotropic regulator 1 JBrowse link 2 182,040,338 182,056,669 RGD:1624291
RGD:13792537
RGD:1600115
G Prpf19 pre-mRNA processing factor 19 JBrowse link 1 226,947,065 226,958,147 RGD:1624291
RGD:1600115
G Pura purine rich element binding protein A JBrowse link 18 29,104,712 29,114,918 RGD:1624291
RGD:1600115
G Purb purine rich element binding protein B JBrowse link 14 86,736,876 86,739,335 RGD:1600115
RGD:1624291
G Rpa1 replication protein A1 JBrowse link 10 62,140,419 62,191,518 RGD:2307012
RGD:13792537
RGD:1624291
RGD:2307013
G Rpa2 replication protein A2 JBrowse link 5 150,957,041 150,967,597 RGD:2307012
RGD:13792537
RGD:1624291
RGD:2307013
G Rpa3 replication protein A3 JBrowse link 4 34,279,320 34,282,351 RGD:2307013
RGD:13792537
RGD:1624291
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 JBrowse link 9 79,943,775 79,990,230 RGD:1600115
RGD:13792537
RGD:1624291
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:13792537
G Tonsl tonsoku-like, DNA repair protein JBrowse link 7 117,688,397 117,703,139 RGD:1624291
RGD:1600115
G Xpa XPA, DNA damage recognition and repair factor JBrowse link 5 61,749,767 61,793,641 RGD:1624291
DNA replication factor C complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rfc1 replication factor C subunit 1 JBrowse link 14 44,627,528 44,702,205 RGD:1624291
G Rfc2 replication factor C subunit 2 JBrowse link 12 25,130,375 25,143,480 RGD:1624291
RGD:13792537
G Rfc3 replication factor C subunit 3 JBrowse link 12 1,460,581 1,471,344 RGD:1624291
RGD:13792537
G Rfc4 replication factor C subunit 4 JBrowse link 11 81,358,592 81,373,044 RGD:1624291
RGD:13792537
G Rfc5 replication factor C subunit 5 JBrowse link 12 44,931,494 44,941,051 RGD:1624291
RGD:13792537
nuclear replication fork term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baz1b bromodomain adjacent to zinc finger domain, 1B JBrowse link 12 24,478,882 24,536,851 RGD:1624291
G Etaa1 ETAA1 activator of ATR kinase JBrowse link 14 102,290,655 102,293,674 RGD:1624291
RGD:13792537
G Mms22l MMS22-like, DNA repair protein JBrowse link 5 38,844,502 38,960,989 RGD:1624291
RGD:13792537
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:1624291
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 JBrowse link 19 30,936,703 30,969,454 RGD:1624291
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` JBrowse link 4 95,884,020 95,945,248 RGD:1624291
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 JBrowse link 9 79,943,775 79,990,230 RGD:13792537
G Tonsl tonsoku-like, DNA repair protein JBrowse link 7 117,688,397 117,703,139 RGD:1600115
RGD:1624291
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 JBrowse link 15 24,021,674 24,056,073 RGD:13792537
G Zmiz2 zinc finger, MIZ-type containing 2 JBrowse link 14 86,645,875 86,662,419 RGD:1624291
G Zranb3 zinc finger RANBP2-type containing 3 JBrowse link 13 44,661,375 44,812,430 RGD:1624291
RGD:13792537
replication fork protection complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:13792537
G Gins2 GINS complex subunit 2 JBrowse link 19 54,151,048 54,163,701 RGD:13792537
G Gins4 GINS complex subunit 4 JBrowse link 16 73,584,412 73,596,808 RGD:13792537
G Mcm10 minichromosome maintenance 10 replication initiation factor JBrowse link 17 77,224,218 77,245,486 RGD:13792537
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:13792537
G Tipin timeless interacting protein JBrowse link 8 69,753,363 69,768,640 RGD:13792537
G Tipinl1 TIMELESS interacting protein like 1 JBrowse link 5 173,761 174,959 RGD:13792537
G Top1 DNA topoisomerase I JBrowse link 3 156,635,688 156,717,686 RGD:13792537
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 JBrowse link 15 24,021,674 24,056,073 RGD:13792537
replisome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Donson DNA replication fork stabilization factor DONSON JBrowse link 11 31,834,608 31,847,751 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19809
    cellular anatomical entity 19424
      replication fork 73
        DNA replication factor C complex + 5
        cytoplasmic replication fork + 0
        nuclear replication fork + 41
        replisome + 24
Path 2
Term Annotations click to browse term
  cellular_component 19809
    cellular anatomical entity 19424
      organelle 12542
        non-membrane-bounded organelle 4631
          intracellular non-membrane-bounded organelle 4612
            chromosome 1101
              replication fork 73
                DNA replication factor C complex + 5
                cytoplasmic replication fork + 0
                nuclear replication fork + 41
                replisome + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.