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ONTOLOGY REPORT - ANNOTATIONS


Term:rough endoplasmic reticulum
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Accession:GO:0005791 term browser browse the term
Definition:The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
Synonyms:exact_synonym: RER;   rough ER
 xref: NIF_Subcellular:sao1881364067;   Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum


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rough endoplasmic reticulum term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:2301205
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:2315987
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:10054252
G Aqp2 aquaporin 2 JBrowse link 7 141,237,802 141,242,837 RGD:1581707
G Arsb arylsulfatase B JBrowse link 2 23,385,154 23,543,028 RGD:1599233
G Baiap2 BAR/IMD domain containing adaptor protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:11576288
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:2316179
G Ca4 carbonic anhydrase 4 JBrowse link 10 72,272,286 72,281,069 RGD:1624291
RGD:1600115
G Canx calnexin JBrowse link 10 35,800,942 35,833,939 RGD:2313162
G Ccdc47 coiled-coil domain containing 47 JBrowse link 10 94,388,425 94,406,949 RGD:1624291
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549739
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 JBrowse link 17 36,451,031 37,157,882 RGD:1624291
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:2313571
G Ckap4 cytoskeleton-associated protein 4 JBrowse link 7 24,935,243 24,947,595 RGD:1624291
RGD:13792537
G Clock clock circadian regulator JBrowse link 14 34,418,226 34,502,218 RGD:10401943
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5131267
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:1599676
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:1624291
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:13792537
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:5688770
G Fkrp fukutin related protein JBrowse link 1 78,733,461 78,740,803 RGD:1624291
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:11041080
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301551
RGD:2301552
G Grm7 glutamate metabotropic receptor 7 JBrowse link 4 142,452,616 143,368,460 RGD:1643599
G Hcrt hypocretin neuropeptide precursor JBrowse link 10 88,669,216 88,670,430 RGD:1600115
G Hgfac HGF activator JBrowse link 14 80,966,902 80,973,525 RGD:1624291
RGD:13792537
G Hm13 histocompatibility minor 13 JBrowse link 3 148,150,695 148,189,623 RGD:1624291
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 13 111,946,626 111,996,536 RGD:1625110
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1625123
RGD:2298714
G Htr5a 5-hydroxytryptamine receptor 5A JBrowse link 4 199,916 209,599 RGD:2316992
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480682
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:7247433
G Lin28a lin-28 homolog A JBrowse link 5 152,230,343 152,247,873 RGD:1624291
G LOC108350501 40S ribosomal protein S29 JBrowse link 3 147,490,388 147,490,712 RGD:1600115
G LOC108351482 40S ribosomal protein S29 JBrowse link 7 76,980,025 76,980,338 RGD:1600115
G LOC108352650 40S ribosomal protein S29 JBrowse link 13 91,333,998 91,334,323 RGD:1600115
G Lrat lecithin retinol acyltransferase JBrowse link 2 181,896,304 181,905,366 RGD:6893660
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:10412055
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:1625439
G Mpz myelin protein zero JBrowse link 13 89,524,204 89,530,070 RGD:9685789
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:9685810
G Mta1 metastasis associated 1 JBrowse link 6 137,911,302 137,950,066 RGD:1600115
G Mttp microsomal triglyceride transfer protein JBrowse link 2 243,366,181 243,407,608 RGD:1582567
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:1600115
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1599676
G Ncoa2 nuclear receptor coactivator 2 JBrowse link 5 5,466,544 5,696,540 RGD:2326122
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:5508789
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:8655644
G Nucb1 nucleobindin 1 JBrowse link 1 101,480,160 101,511,029 RGD:9831129
G P2rx3 purinergic receptor P2X 3 JBrowse link 3 72,403,992 72,447,801 RGD:1642677
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 2 91,450,162 91,497,091 RGD:2308915
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1582517
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:2302814
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 JBrowse link 12 22,716,421 22,726,982 RGD:1600115
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:1624291
RGD:1600115
G Rab14 RAB14, member RAS oncogene family JBrowse link 3 14,373,270 14,395,357 RGD:8554557
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1624291
G Rpl18 ribosomal protein L18 JBrowse link 1 101,700,910 101,703,551 RGD:1600115
G Rpl4 ribosomal protein L4 JBrowse link 8 69,121,682 69,126,805 RGD:1600115
RGD:1624291
G Rpl6 ribosomal protein L6 JBrowse link 12 40,877,578 40,882,032 RGD:1600115
G Rpn1 ribophorin I JBrowse link 4 119,997,232 120,018,687 RGD:1625439
RGD:1600115
RGD:1624291
G Rpn2 ribophorin II JBrowse link 3 153,398,373 153,445,633 RGD:1625439
RGD:2325967
G Rps21 ribosomal protein S21 JBrowse link 3 175,629,176 175,630,198 RGD:1600115
G Rps23 ribosomal protein S23 JBrowse link 2 19,823,234 19,824,804 RGD:1600115
G Rps29 ribosomal protein S29 JBrowse link 6 91,455,333 91,456,709 RGD:1600115
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:5144115
G Sec61a1 SEC61 translocon subunit alpha 1 JBrowse link 4 120,453,577 120,467,932 RGD:68306
G Sftpa1 surfactant protein A1 JBrowse link 16 18,716,019 18,719,404 RGD:4143471
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:4143471
RGD:13792537
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:2315030
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6218996
G Sppl3 signal peptide peptidase like 3 JBrowse link 12 47,276,485 47,360,552 RGD:1624291
G Stx17 syntaxin 17 JBrowse link 5 63,866,346 63,926,276 RGD:1624291
G Suco SUN domain containing ossification factor JBrowse link 13 79,736,485 79,801,133 RGD:1600115
RGD:1624291
G Tmcc1 transmembrane and coiled-coil domain family 1 JBrowse link 4 147,920,987 148,048,852 RGD:1624291
G Tmem97 transmembrane protein 97 JBrowse link 10 65,811,455 65,820,538 RGD:1624291
RGD:1600115
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1625439
G Tram1 translocation associated membrane protein 1 JBrowse link 5 5,215,196 5,297,337 RGD:13792537
G Tram1l1 translocation associated membrane protein 1-like 1 JBrowse link 2 228,544,418 228,546,599 RGD:13792537
G Tram2 translocation associated membrane protein 2 JBrowse link 9 27,117,861 27,192,166 RGD:13792537
G Vdac3 voltage-dependent anion channel 3 JBrowse link 16 74,292,466 74,308,910 RGD:1625439
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
RGD:1624291
cytoplasmic side of rough endoplasmic reticulum membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epm2a EPM2A glucan phosphatase, laforin JBrowse link 1 5,448,958 5,571,512 RGD:1624291
RGD:1600115
G Gnrh1 gonadotropin releasing hormone 1 JBrowse link 15 44,441,856 44,446,064 RGD:9685146
G LOC100360508 ribosomal protein S26-like JBrowse link 13 45,079,857 45,080,277 RGD:1600115
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase JBrowse link 6 91,476,698 91,479,187 RGD:1624291
G Rpl10 ribosomal protein L10 JBrowse link X 156,438,251 156,440,461 RGD:1624291
G Rpl11 ribosomal protein L11 JBrowse link 5 154,390,809 154,394,412 RGD:1624291
G Rpl22 ribosomal protein L22 JBrowse link 5 169,506,150 169,512,875 RGD:1624291
G Rpl23 ribosomal protein L23 JBrowse link 10 85,721,398 85,725,359 RGD:1624291
G Rpl27 ribosomal protein L27 JBrowse link 10 89,352,864 89,356,563 RGD:1600115
RGD:1624291
G Rpl29 ribosomal protein L29 JBrowse link 8 115,131,228 115,133,401 RGD:1624291
G Rpl31 ribosomal protein L31 JBrowse link 9 46,086,959 46,090,444 RGD:1624291
G Rpl32 ribosomal protein L32 JBrowse link 4 147,715,480 147,719,044 RGD:1624291
G Rpl35 ribosomal protein L35 JBrowse link 3 23,294,813 23,297,774 RGD:1624291
G Rps17 ribosomal protein S17 JBrowse link 1 143,167,329 143,169,915 RGD:1624291
G Rps18 ribosomal protein S18 JBrowse link 20 5,441,875 5,445,553 RGD:1624291
G Rps20 ribosomal protein S20 JBrowse link 5 16,706,052 16,707,214 RGD:1624291
G Rps21-ps1 ribosomal protein S21, pseudogene 1 JBrowse link 5 159,606,647 159,606,990 RGD:1624291
G Rps23 ribosomal protein S23 JBrowse link 2 19,823,234 19,824,804 RGD:1624291
G Rps26 ribosomal protein S26 JBrowse link 7 3,052,112 3,053,662 RGD:1600115
G Rps28 ribosomal protein S28 JBrowse link 7 18,682,071 18,683,440 RGD:1600115
RGD:1624291
G Rps29 ribosomal protein S29 JBrowse link 6 91,455,333 91,456,709 RGD:1624291
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
G Rpsa ribosomal protein SA JBrowse link 8 128,806,053 128,809,987 RGD:1624291
endoplasmic reticulum Sec complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sec61b SEC61 translocon subunit beta JBrowse link 5 63,192,322 63,200,532 RGD:13792537
rough endoplasmic reticulum lumen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:1624291
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:8662311
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:1641935
RGD:13792537
RGD:1624291
G Lyz2 lysozyme 2 JBrowse link 7 60,335,968 60,341,264 RGD:1599861
G Resp18 regulated endocrine-specific protein 18 JBrowse link 9 82,470,794 82,477,136 RGD:69957
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:10003091
rough endoplasmic reticulum membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldob aldolase, fructose-bisphosphate B JBrowse link 5 64,805,772 64,818,813 RGD:2313431
G Ccdc47 coiled-coil domain containing 47 JBrowse link 10 94,388,425 94,406,949 RGD:1600115
G Maco1 macoilin 1 JBrowse link 5 153,122,780 153,184,940 RGD:1624291
RGD:13792537
RGD:1600115
G Nat8l N-acetyltransferase 8-like JBrowse link 14 82,041,616 82,048,251 RGD:1600115
G Pi4kb phosphatidylinositol 4-kinase beta JBrowse link 2 196,139,724 196,172,055 RGD:1600115
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 JBrowse link 5 164,720,629 164,747,071 RGD:1600115
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 JBrowse link 8 99,977,334 100,059,736 RGD:1600115
G Rho rhodopsin JBrowse link 4 147,832,136 147,837,298 RGD:6893558
G Suco SUN domain containing ossification factor JBrowse link 13 79,736,485 79,801,133 RGD:1600115
G Tmem97 transmembrane protein 97 JBrowse link 10 65,811,455 65,820,538 RGD:1600115
G Uba1 ubiquitin-like modifier activating enzyme 1 JBrowse link X 1,723,135 1,745,147 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
Sec61 translocon complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 JBrowse link 1 187,770,160 187,779,675 RGD:1624291
RGD:13792537
G Sec61a1 SEC61 translocon subunit alpha 1 JBrowse link 4 120,453,577 120,467,932 RGD:13792537
G Sec61a2 SEC61 translocon subunit alpha 2 JBrowse link 17 76,358,947 76,385,860 RGD:13792537
G Sec61b SEC61 translocon subunit beta JBrowse link 5 63,192,322 63,200,532 RGD:1600115
G Ssr3 signal sequence receptor subunit 3 JBrowse link 2 156,010,997 156,023,853 RGD:61758
G Ssr4 signal sequence receptor subunit 4 JBrowse link X 156,995,763 156,999,702 RGD:61758
Sec62/Sec63 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sec63 SEC63 homolog, protein translocation regulator JBrowse link 20 47,494,270 47,563,222 RGD:13792537
signal recognition particle receptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:1624291
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
G Rp9 RP9, pre-mRNA splicing factor JBrowse link 8 23,450,111 23,482,939 RGD:1624291
G Srpra SRP receptor subunit alpha JBrowse link 8 36,410,683 36,416,766 RGD:1600115
Ssh1 translocon complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07028668.1 RGD:13792537
G LOC499136 LRRGT00021 JBrowse link 1 97,783,806 97,785,490 RGD:13792537
G Sec61g SEC61 translocon subunit gamma JBrowse link 14 99,774,589 99,780,964 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19951
    intracellular 13934
      cytoplasm 10687
        endoplasmic reticulum 1302
          rough endoplasmic reticulum 131
            rough endoplasmic reticulum lumen 6
            rough endoplasmic reticulum membrane + 50
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        membrane-bounded organelle 10978
          intracellular membrane-bounded organelle 10066
            endoplasmic reticulum 1302
              rough endoplasmic reticulum 131
                rough endoplasmic reticulum lumen 6
                rough endoplasmic reticulum membrane + 50
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.