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ONTOLOGY REPORT - ANNOTATIONS


Term:centriole
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Accession:GO:0005814 term browser browse the term
Definition:A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
Comment:In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.
Synonyms:narrow_synonym: daughter centriole;   mother centriole
 xref: NIF_Subcellular:sao95019936;   Wikipedia:Centriole


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centriole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07049064.1 RGD:13792537
G Actr1a actin related protein 1A JBrowse link 1 266,123,864 266,142,621 RGD:11541119
G Agbl2 ATP/GTP binding protein-like 2 JBrowse link 3 79,622,791 79,647,402 RGD:1624291
G Agbl4 ATP/GTP binding protein-like 4 JBrowse link 5
5
130,742,297
130,286,393
131,656,581
130,305,884
RGD:1624291
G Ahi1 Abelson helper integration site 1 JBrowse link 1 16,478,127 16,601,769 RGD:1624291
RGD:1600115
G Akna AT-hook transcription factor JBrowse link 5 79,184,087 79,232,370 RGD:1624291
G Alms1 ALMS1, centrosome and basal body associated protein JBrowse link 4 117,371,544 117,472,310 RGD:8696019
RGD:13792537
RGD:1624291
G Armc9 armadillo repeat containing 9 JBrowse link 9 93,172,718 93,299,119 RGD:1624291
RGD:13792537
RGD:1600115
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:1600115
G Bbs4 Bardet-Biedl syndrome 4 JBrowse link 8 64,115,005 64,154,432 RGD:1624291
G Bccip BRCA2 and CDKN1A interacting protein JBrowse link 1 205,777,474 205,789,887 RGD:1624291
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:1624291
RGD:1600115
G Bnip2 BCL2 interacting protein 2 JBrowse link 8 76,400,333 76,426,307 RGD:1624291
G C2cd3 C2 domain containing 3 centriole elongation regulator JBrowse link 1 165,382,279 165,480,088 RGD:1624291
G Capg capping actin protein, gelsolin like JBrowse link 4 100,395,693 100,419,447 RGD:1624291
G Cby1 chibby family member 1, beta catenin antagonist JBrowse link 7 120,891,930 120,898,318 RGD:1624291
G Ccdc120 coiled-coil domain containing 120 JBrowse link X 15,610,230 15,616,727 RGD:1624291
G Ccdc146 coiled-coil domain containing 146 JBrowse link 4 10,269,798 10,421,724 RGD:1624291
RGD:1600115
G Ccdc151 coiled-coil domain containing 151 JBrowse link 8 23,000,912 23,014,707 RGD:1624291
G Ccdc68 coiled-coil domain containing 68 JBrowse link 18 68,408,812 68,472,323 RGD:1624291
G Ccdc78 coiled-coil domain containing 78 JBrowse link 10 15,155,839 15,160,039 RGD:1624291
G Ccdc88a coiled coil domain containing 88A JBrowse link 14 113,771,093 113,936,376 RGD:1624291
G Ccdc92 coiled-coil domain containing 92 JBrowse link 12 37,210,735 37,237,848 RGD:1624291
RGD:13792537
G Cchcr1 coiled-coil alpha-helical rod protein 1 JBrowse link 20 3,730,968 3,745,721 RGD:1624291
RGD:13792537
G Ccnf cyclin F JBrowse link 10 13,594,687 13,619,935 RGD:1624291
RGD:1600115
G Ccp110 centriolar coiled-coil protein 110 JBrowse link 1 188,417,012 188,444,991 RGD:1624291
RGD:13792537
G Ccsap centriole, cilia and spindle-associated protein JBrowse link 19 56,615,326 56,634,031 RGD:1624291
RGD:13792537
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
RGD:13792537
G Cep104 centrosomal protein 104 JBrowse link 5 171,262,278 171,294,560 RGD:1624291
G Cep120 centrosomal protein 120 JBrowse link 18 48,658,495 48,720,570 RGD:1624291
G Cep128 centrosomal protein 128 JBrowse link 6 114,759,474 115,158,004 RGD:1624291
G Cep135 centrosomal protein 135 JBrowse link 14 34,052,168 34,115,763 RGD:1624291
G Cep152 centrosomal protein 152 JBrowse link 3 117,822,799 117,894,856 RGD:1624291
G Cep162 centrosomal protein 162 JBrowse link 8 94,863,282 94,921,917 RGD:1624291
RGD:1600115
G Cep164 centrosomal protein 164 JBrowse link 8 50,069,282 50,132,477 RGD:1624291
RGD:13792537
G Cep170 centrosomal protein 170 JBrowse link 13 94,807,090 94,887,448 RGD:1624291
G Cep19 centrosomal protein 19 JBrowse link 11 71,921,713 71,938,335 RGD:1600115
RGD:13792537
RGD:1624291
G Cep250 centrosomal protein 250 JBrowse link 3 151,508,366 151,544,631 RGD:1624291
G Cep290 centrosomal protein 290 JBrowse link 7 40,217,269 40,306,327 RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:1600115
RGD:13792537
RGD:1624291
G Cep295nl CEP295 N-terminal like JBrowse link 10 107,363,511 107,381,280 RGD:13792537
G Cep350 centrosomal protein 350 JBrowse link 13 73,499,715 73,637,707 RGD:1624291
G Cep41 centrosomal protein 41 JBrowse link 4 57,966,783 58,006,931 RGD:1600115
RGD:1624291
G Cep43 centrosomal protein 43 JBrowse link 1 53,122,330 53,152,872 RGD:1624291
G Cep55 centrosomal protein 55 JBrowse link 1 256,745,251 256,760,794 RGD:1600115
G Cep63 centrosomal protein 63 JBrowse link 8 111,063,988 111,116,014 RGD:1624291
RGD:13792537
RGD:1600115
G Cep76 centrosomal protein 76 JBrowse link 18 63,364,990 63,394,766 RGD:1624291
G Cep83 centrosomal protein 83 JBrowse link 7 35,739,553 35,847,618 RGD:1600115
RGD:1624291
G Cep89 centrosomal protein 89 JBrowse link 1 91,663,723 91,705,979 RGD:1624291
G Cetn1 centrin 1 JBrowse link 18 785,972 786,674 RGD:1624291
RGD:13792537
G Cetn2 centrin 2 JBrowse link X 152,927,852 152,933,095 RGD:1624291
RGD:13792537
G Cetn3 centrin 3 JBrowse link 2 12,101,473 12,115,009 RGD:1624291
G Cetn4 centrin 4 JBrowse link 2 124,045,092 124,048,441 RGD:13792537
G Cfap20 cilia and flagella associated protein 20 JBrowse link 19 10,024,938 10,038,838 RGD:1600115
RGD:1624291
G Cibar1 CBY1 interacting BAR domain containing 1 JBrowse link 5 25,732,457 25,750,953 RGD:1624291
G Cntln centlein JBrowse link 5 103,251,986 103,367,088 RGD:1624291
RGD:13792537
G Cntrob centrobin, centriole duplication and spindle assembly protein JBrowse link 10 55,901,929 55,927,121 RGD:1624291
RGD:13792537
G Crocc ciliary rootlet coiled-coil, rootletin JBrowse link 5 159,540,453 159,583,194 RGD:1624291
G Dctn1 dynactin subunit 1 JBrowse link 4 114,876,770 114,896,567 RGD:1600115
RGD:1624291
G Deup1 deuterosome assembly protein 1 JBrowse link 8 14,094,742 14,157,232 RGD:13792537
G Dync2i2 dynein 2 intermediate chain 2 JBrowse link 3 8,599,251 8,615,329 RGD:1624291
G Dzip1 DAZ interacting zinc finger protein 1 JBrowse link 15 104,117,551 104,168,574 RGD:1624291
G Dzip1l DAZ interacting zinc finger protein 1-like JBrowse link 8 107,875,659 107,916,298 RGD:1624291
RGD:1600115
G Fam161a FAM161 centrosomal protein A JBrowse link 14 107,785,029 107,803,765 RGD:1624291
G Fbf1 Fas binding factor 1 JBrowse link 10 104,692,791 104,718,630 RGD:1624291
RGD:13792537
G Ftcd formimidoyltransferase cyclodeaminase JBrowse link 20 12,806,957 12,820,466 RGD:1600115
G Gle1 GLE1 RNA export mediator JBrowse link 3 8,498,098 8,530,218 RGD:1624291
G Hap1 huntingtin-associated protein 1 JBrowse link 10 88,257,975 88,266,210 RGD:1624291
RGD:1600115
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:1624291
RGD:1600115
G Ift140 intraflagellar transport 140 JBrowse link 10 14,373,668 14,461,509 RGD:1624291
G Ift20 intraflagellar transport 20 JBrowse link 10 65,805,808 65,811,353 RGD:1624291
G Ift52 intraflagellar transport 52 JBrowse link 3 159,388,868 159,413,358 RGD:1624291
RGD:13792537
G Ift88 intraflagellar transport 88 JBrowse link 15 37,690,417 37,786,855 RGD:1624291
RGD:13792537
G Kif24 kinesin family member 24 JBrowse link 5 57,778,730 57,845,642 RGD:1624291
G Kif2a kinesin family member 2A JBrowse link 2 38,145,507 38,208,765 RGD:1600115
RGD:1624291
G Kif3a kinesin family member 3a JBrowse link 10 38,918,705 38,953,958 RGD:1624291
G LOC100302465 hypothetical LOC100302465 JBrowse link 1 206,324,763 206,417,143 RGD:13792537
G LOC100911256 ninein-like JBrowse link 6 91,207,750 91,273,661 RGD:13792537
G LOC690035 similar to Protein KIAA0586 JBrowse link 6 93,562,775 93,667,857 RGD:13792537
G Mapk15 mitogen-activated protein kinase 15 JBrowse link 7 117,041,287 117,061,799 RGD:1600115
RGD:1624291
G Mdm1 Mdm1 nuclear protein JBrowse link 7 61,165,652 61,200,865 RGD:1624291
RGD:1600115
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1624291
RGD:1600115
G Mphosph9 M-phase phosphoprotein 9 JBrowse link 12 37,700,282 37,766,487 RGD:1624291
RGD:13792537
G Nedd1 NEDD1 gamma-tubulin ring complex targeting factor JBrowse link 7 33,544,097 33,584,406 RGD:1624291
RGD:13792537
G Nin ninein JBrowse link 6 92,423,412 92,527,776 RGD:1624291
RGD:13792537
G Nubp1 nucleotide binding protein 1 JBrowse link 10 5,333,378 5,343,949 RGD:1600115
G Nubp2 nucleotide binding protein 2 JBrowse link 10 14,244,201 14,247,930 RGD:1600115
G Odf2 outer dense fiber of sperm tails 2 JBrowse link 3 8,449,733 8,495,764 RGD:1624291
G Ofd1 OFD1, centriole and centriolar satellite protein JBrowse link X 29,562,165 29,602,934 RGD:1624291
RGD:13792537
G Pcm1 pericentriolar material 1 JBrowse link 16 54,040,721 54,137,675 RGD:1624291
RGD:13792537
G Pcnt pericentrin JBrowse link 20 12,943,523 13,038,615 RGD:1624291
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1624291
RGD:1600115
G Plk2 polo-like kinase 2 JBrowse link 2 41,911,143 41,916,901 RGD:1624291
RGD:13792537
RGD:1600115
G Plk4 polo-like kinase 4 JBrowse link 2 127,686,911 127,705,518 RGD:1600115
RGD:1624291
G Poc1a POC1 centriolar protein A JBrowse link 8 114,982,764 115,050,844 RGD:1624291
G Poc1b POC1 centriolar protein B JBrowse link 7 41,304,119 41,404,360 RGD:1600115
RGD:1624291
G Poc5 POC5 centriolar protein JBrowse link 2 27,000,303 27,030,646 RGD:1600115
G Rab8a RAB8A, member RAS oncogene family JBrowse link 16 19,355,047 19,376,776 RGD:1600115
G Rabl2 RAB, member of RAS oncogene family like 2 JBrowse link 7 130,556,056 130,564,764 RGD:1624291
G Ran RAN, member RAS oncogene family JBrowse link 12 31,319,556 31,324,105 RGD:1624291
G Rilpl1 Rab interacting lysosomal protein-like 1 JBrowse link 12 37,490,320 37,528,393 RGD:1600115
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1600115
G Rp2 RP2 activator of ARL3 GTPase JBrowse link X 2,066,298 2,116,661 RGD:1624291
G Rttn rotatin JBrowse link 18 86,071,884 86,247,486 RGD:13792537
G Sass6 SAS-6 centriolar assembly protein JBrowse link 2 219,626,851 219,660,975 RGD:1624291
G Saxo1 stabilizer of axonemal microtubules 1 JBrowse link 5 104,771,081 104,921,001 RGD:1624291
RGD:13792537
G Saxo2 stabilizer of axonemal microtubules 2 JBrowse link 1 144,586,260 144,601,358 RGD:13792537
G Saxol1 stabilizer of axonemal microtubules like 1 JBrowse link X 29,520,263 29,522,420 RGD:1600115
RGD:13792537
G Sclt1 sodium channel and clathrin linker 1 JBrowse link 2 128,523,376 128,675,668 RGD:1624291
RGD:1600115
G Sdccag8 SHH signaling and ciliogenesis regulator SDCCAG8 JBrowse link 13 94,888,046 95,100,833 RGD:1624291
RGD:13792537
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:1600115
RGD:1624291
G Spice1 spindle and centriole associated protein 1 JBrowse link 11 61,250,649 61,294,116 RGD:1624291
RGD:13792537
RGD:1600115
G Stard9 StAR-related lipid transfer domain containing 9 JBrowse link 3 112,428,361 112,659,558 RGD:1624291
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
RGD:13792537
G Tcp10b t-complex protein 10b JBrowse link 1 53,530,992 53,554,113 RGD:13792537
G Tedc1 tubulin epsilon and delta complex 1 JBrowse link 6 137,967,119 137,976,324 RGD:1624291
G Tedc2 tubulin epsilon and delta complex 2 JBrowse link 10 13,586,852 13,591,938 RGD:1624291
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:1600115
RGD:1624291
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase JBrowse link 5 56,554,956 56,566,503 RGD:1624291
G Tsga10 testis specific 10 JBrowse link 9 44,351,655 44,456,576 RGD:1600115
G Tsks testis-specific serine kinase substrate JBrowse link 1 100,926,569 100,953,950 RGD:1600115
RGD:13792537
RGD:1624291
G Tssk2 testis-specific serine kinase 2 JBrowse link 11 87,235,058 87,236,413 RGD:1624291
RGD:1600115
G Ttbk2 tau tubulin kinase 2 JBrowse link 3 112,677,932 112,789,615 RGD:1624291
G Tubg1 tubulin, gamma 1 JBrowse link 10 89,030,865 89,037,455 RGD:1624291
G Tubgcp3 tubulin, gamma complex associated protein 3 JBrowse link 16 82,184,362 82,245,041 RGD:1624291
G Wdr90 WD repeat domain 90 JBrowse link 10 15,211,660 15,229,477 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19949
    cellular anatomical entity 19598
      microtubule organizing center 756
        centriole 129
Path 2
Term Annotations click to browse term
  cellular_component 19949
    cellular anatomical entity 19598
      organelle 12670
        non-membrane-bounded organelle 4661
          intracellular non-membrane-bounded organelle 4642
            cytoskeleton 2098
              microtubule cytoskeleton 1235
                microtubule organizing center 756
                  centriole 129
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.