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ONTOLOGY REPORT - ANNOTATIONS


Term:centriole
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Accession:GO:0005814 term browser browse the term
Definition:A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
Comment:In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.
Synonyms:narrow_synonym: daughter centriole;   mother centriole
 xref: NIF_Subcellular:sao95019936;   Wikipedia:Centriole


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centriole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTR1A actin related protein 1A JBrowse link 10 102,547,695 102,570,766 RGD:9068941
G AGBL2 ATP/GTP binding protein like 2 JBrowse link 11 48,163,160 48,218,611 RGD:9068941
G AGBL4 ATP/GTP binding protein like 4 JBrowse link 1 49,316,524 50,770,899 RGD:9068941
G AHI1 Abelson helper integration site 1 JBrowse link 6 137,149,457 137,366,731 RGD:9068941
G AKNA AT-hook transcription factor JBrowse link 9 113,798,225 113,858,637 RGD:9068941
G ALMS1 ALMS1 centrosome and basal body associated protein JBrowse link 2A 74,926,650 75,158,734 RGD:9068941
G ARMC9 armadillo repeat containing 9 JBrowse link 2B 237,243,120 237,438,796 RGD:9068941
G AURKA aurora kinase A JBrowse link 20 53,994,880 54,017,381 RGD:9068941
G BBS4 Bardet-Biedl syndrome 4 JBrowse link 15 70,362,007 70,416,964 RGD:9068941
G BCCIP BRCA2 and CDKN1A interacting protein JBrowse link 10 126,648,676 126,678,863 RGD:9068941
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 77,842,724 77,854,159 RGD:9068941
G BNIP2 BCL2 interacting protein 2 JBrowse link 15 56,933,697 56,964,197 RGD:9068941
G C10H10orf90 chromosome 10 C10orf90 homolog JBrowse link 10 127,258,584 127,505,349 RGD:9068941
G C2CD3 C2 domain containing 3 centriole elongation regulator JBrowse link 11 72,392,606 72,551,620 RGD:9068941
G CAPG capping actin protein, gelsolin like JBrowse link 2A 86,997,891 87,022,494 RGD:9068941
G CBY1 chibby family member 1, beta catenin antagonist JBrowse link 22 37,389,924 37,406,879 RGD:9068941
G CCDC120 coiled-coil domain containing 120 JBrowse link X 49,207,391 49,223,622 RGD:9068941
G CCDC146 coiled-coil domain containing 146 JBrowse link 7 82,900,402 83,027,578 RGD:9068941
G CCDC151 coiled-coil domain containing 151 JBrowse link 19 11,678,306 11,694,190 RGD:9068941
G CCDC68 coiled-coil domain containing 68 JBrowse link 18 51,616,129 51,660,189 RGD:9068941
G CCDC78 coiled-coil domain containing 78 JBrowse link 16 735,786 740,155 RGD:9068941
G CCDC88A coiled-coil domain containing 88A JBrowse link 2A 56,585,354 56,716,197 RGD:9068941
G CCDC92 coiled-coil domain containing 92 JBrowse link 12 125,745,846 125,846,832 RGD:9068941
G CCHCR1 coiled-coil alpha-helical rod protein 1 JBrowse link 6 31,753,777 31,769,770 RGD:9068941
G CCNF cyclin F JBrowse link 16 2,526,035 2,558,265 RGD:9068941
G CCP110 centriolar coiled-coil protein 110 JBrowse link 16 19,624,708 19,654,131 RGD:9068941
G CCSAP centriole, cilia and spindle associated protein JBrowse link 1 209,898,803 209,919,392 RGD:9068941
G CENPJ centromere protein J JBrowse link 13 24,464,045 24,503,432 RGD:9068941
G CEP104 centrosomal protein 104 JBrowse link 1 3,607,940 3,649,450 RGD:9068941
G CEP120 centrosomal protein 120 JBrowse link 5 124,514,996 124,593,259 RGD:9068941
G CEP128 centrosomal protein 128 JBrowse link 14 80,235,470 80,704,684 RGD:9068941
G CEP135 centrosomal protein 135 JBrowse link 4 74,463,689 74,547,795 RGD:9068941
G CEP152 centrosomal protein 152 JBrowse link 15 46,011,447 46,084,233 RGD:9068941
G CEP162 centrosomal protein 162 JBrowse link 6 85,293,510 85,396,533 RGD:9068941
G CEP164 centrosomal protein 164 JBrowse link 11 116,096,165 116,181,613 RGD:9068941
G CEP170 centrosomal protein 170 JBrowse link 1 224,107,145 224,238,990 RGD:9068941
G CEP19 centrosomal protein 19 JBrowse link 3 203,990,477 203,996,486 RGD:9068941
G CEP192 centrosomal protein 192 JBrowse link 18 16,327,525 16,460,678 RGD:9068941
G CEP20 centrosomal protein 20 RGD:9068941
G CEP250 centrosomal protein 250 JBrowse link 20 32,903,441 32,959,715 RGD:9068941
G CEP290 centrosomal protein 290 JBrowse link 12 88,896,146 88,988,953 RGD:9068941
G CEP295 centrosomal protein 295 JBrowse link 11 92,170,720 92,239,237 RGD:9068941
G CEP295NL CEP295 N-terminal like JBrowse link 17 78,512,245 78,524,447 RGD:9068941
G CEP350 centrosomal protein 350 JBrowse link 1 159,116,232 159,275,555 RGD:9068941
G CEP41 centrosomal protein 41 JBrowse link 7 134,880,086 134,924,657 RGD:9068941
G CEP43 centrosomal protein 43 JBrowse link 6 169,945,218 169,988,027 RGD:9068941
G CEP55 centrosomal protein 55 JBrowse link 10 93,750,177 93,784,890 RGD:9068941
G CEP63 centrosomal protein 63 JBrowse link 3 139,003,890 139,115,026 RGD:9068941
G CEP76 centrosomal protein 76 JBrowse link 18 16,735,624 16,765,750 RGD:9068941
G CEP78 centrosomal protein 78 JBrowse link 9 77,086,877 77,122,288 RGD:9068941
G CEP83 centrosomal protein 83 JBrowse link 12 95,238,166 95,403,175 RGD:9068941
G CEP89 centrosomal protein 89 JBrowse link 19 38,547,694 38,638,936 RGD:9068941
G CETN1 centrin 1 JBrowse link 18 17,385,106 17,386,772 RGD:9068941
G CETN2 centrin 2 JBrowse link X 152,320,893 152,324,362 RGD:9068941
G CETN3 centrin 3 JBrowse link 5 25,098,973 25,114,676 RGD:9068941
G CFAP20 cilia and flagella associated protein 20 JBrowse link 16 57,524,195 57,539,638 RGD:9068941
G CIBAR1 CBY1 interacting BAR domain containing 1 JBrowse link 8 92,270,482 92,298,846 RGD:9068941
G CIBAR2 CBY1 interacting BAR domain containing 2 JBrowse link 16 85,106,709 85,120,815 RGD:9068941
G CNTLN centlein JBrowse link 9 17,455,498 17,804,123 RGD:9068941
G CNTROB centrobin, centriole duplication and spindle assembly protein JBrowse link 17 7,953,617 7,970,148 RGD:9068941
G CROCC ciliary rootlet coiled-coil, rootletin JBrowse link 1 16,923,682 16,973,999 RGD:9068941
G DCTN1 dynactin subunit 1 JBrowse link 2A 75,934,408 75,965,012 RGD:9068941
G DEUP1 deuterosome assembly protein 1 JBrowse link 11 91,846,096 91,946,993 RGD:9068941
G DYNC2I2 dynein 2 intermediate chain 2 JBrowse link 9 128,422,958 128,447,444 RGD:9068941
G DZIP1 DAZ interacting zinc finger protein 1 JBrowse link 13 95,912,026 95,975,563 RGD:9068941
G DZIP1L DAZ interacting zinc finger protein 1 like JBrowse link 3 142,540,798 142,591,297 RGD:9068941
G FBF1 Fas binding factor 1 JBrowse link 17 75,410,069 75,440,370 RGD:9068941
G FTCD formimidoyltransferase cyclodeaminase JBrowse link 21 45,734,647 45,753,437 RGD:9068941
G GLE1 GLE1 RNA export mediator JBrowse link 9 128,294,607 128,331,301 RGD:9068941
G HAP1 huntingtin associated protein 1 JBrowse link 17 15,797,949 15,810,299 RGD:9068941
G HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 JBrowse link 15 25,535,760 25,746,444 RGD:9068941
G HTT huntingtin JBrowse link 4 3,116,810 3,287,644 RGD:9068941
G HYLS1 HYLS1 centriolar and ciliogenesis associated JBrowse link 11 124,615,837 124,629,444 RGD:9068941
G IFT140 intraflagellar transport 140 JBrowse link 16 1,566,309 1,662,833 RGD:9068941
G IFT20 intraflagellar transport 20 JBrowse link 17 28,941,303 28,948,129 RGD:9068941
G IFT52 intraflagellar transport 52 JBrowse link 20 41,023,517 41,080,500 RGD:9068941
G IFT88 intraflagellar transport 88 JBrowse link 13 20,205,881 20,331,204 RGD:9068941
G IQCB1 IQ motif containing B1 JBrowse link 3 125,779,453 125,844,242 RGD:9068941
G KIAA0586 KIAA0586 ortholog JBrowse link 14 57,287,138 57,405,914 RGD:9068941
G KIAA0753 KIAA0753 ortholog JBrowse link 17 6,603,983 6,666,231 RGD:9068941
G KIF24 kinesin family member 24 JBrowse link 9 34,898,729 34,973,978 RGD:9068941
G KIF2A kinesin family member 2A JBrowse link 5 53,251,415 53,332,218 RGD:9068941
G KIF3A kinesin family member 3A JBrowse link 5 134,268,505 134,315,431 RGD:9068941
G LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 JBrowse link 8 83,250,077 83,287,999 RGD:9068941
G MAPK15 mitogen-activated protein kinase 15 JBrowse link 8 143,482,245 143,488,498 RGD:9068941
G MDM1 Mdm1 nuclear protein JBrowse link 12 68,588,541 68,626,359 RGD:9068941
G MKS1 MKS transition zone complex subunit 1 JBrowse link 17 57,137,254 57,151,122 RGD:9068941
G MPHOSPH9 M-phase phosphoprotein 9 JBrowse link 12 124,991,210 125,065,203 RGD:9068941
G NEDD1 NEDD1 gamma-tubulin ring complex targeting factor JBrowse link 12 97,914,112 97,959,953 RGD:9068941
G NEURL4 neuralized E3 ubiquitin protein ligase 4 JBrowse link 17 7,336,447 7,349,407 RGD:9068941
G NIN ninein JBrowse link 14 49,609,367 49,719,971 RGD:9068941
G NUBP1 nucleotide binding protein 1 JBrowse link 16 10,906,347 10,931,799 RGD:9068941
G NUBP2 nucleotide binding protein 2 JBrowse link 16 1,836,186 1,842,752 RGD:9068941
G ODF2 outer dense fiber of sperm tails 2 JBrowse link 9 128,245,049 128,291,206 RGD:9068941
G ODF2L outer dense fiber of sperm tails 2 like JBrowse link 1 87,731,664 87,780,838 RGD:9068941
G OFD1 OFD1 centriole and centriolar satellite protein JBrowse link X 13,630,006 13,669,285 RGD:9068941
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 3 53,112,494 53,119,053 RGD:9068941
G PCM1 pericentriolar material 1 JBrowse link 8 14,093,976 14,199,691 RGD:9068941
G PCNT pericentrin JBrowse link 21 45,914,665 46,042,990 RGD:9068941
G PLA2G3 phospholipase A2 group III JBrowse link 22 29,995,364 30,001,160 RGD:9068941
G PLK1 polo like kinase 1 JBrowse link 16 23,928,773 23,940,779 RGD:9068941
G PLK2 polo like kinase 2 JBrowse link 5 57,178,503 57,184,793 RGD:9068941
G PLK4 polo like kinase 4 JBrowse link 4 131,349,562 131,367,832 RGD:9068941
G POC1A POC1 centriolar protein A JBrowse link 3 53,245,162 53,324,579 RGD:9068941
G POC1B POC1 centriolar protein B JBrowse link 12 90,267,207 90,373,735 RGD:9068941
G POC5 POC5 centriolar protein JBrowse link 5 40,201,170 40,244,189 RGD:9068941
G RAB8A RAB8A, member RAS oncogene family JBrowse link 19 16,580,720 16,602,189 RGD:9068941
G RAN RAN, member RAS oncogene family JBrowse link 12 132,694,498 132,699,668 RGD:9068941
G RILPL1 Rab interacting lysosomal protein like 1 JBrowse link 12 125,295,534 125,356,076 RGD:9068941
G ROCK1 Rho associated coiled-coil containing protein kinase 1 JBrowse link 18 17,831,594 17,991,039 RGD:9068941
G RP2 RP2 activator of ARL3 GTPase JBrowse link X 47,133,639 47,178,608 RGD:9068941
G RTTN rotatin JBrowse link 18 66,674,250 66,874,390 RGD:9068941
G SASS6 SAS-6 centriolar assembly protein JBrowse link 1 101,457,559 101,506,348 RGD:9068941
G SAXO1 stabilizer of axonemal microtubules 1 JBrowse link 9 19,234,977 19,346,886 RGD:9068941
G SAXO2 stabilizer of axonemal microtubules 2 RGD:9068941
G SCLT1 sodium channel and clathrin linker 1 JBrowse link 4 132,345,394 132,551,619 RGD:9068941
G SDCCAG8 SHH signaling and ciliogenesis regulator SDCCAG8 JBrowse link 1 224,238,840 224,481,133 RGD:9068941
G SFI1 SFI1 centrin binding protein JBrowse link 22 30,378,363 30,495,602 RGD:9068941
G SIRT2 sirtuin 2 JBrowse link 19 44,533,965 44,554,838 RGD:9068941
G SPICE1 spindle and centriole associated protein 1 JBrowse link 3 117,507,941 117,579,180 RGD:9068941
G STARD9 StAR related lipid transfer domain containing 9 JBrowse link 15 39,692,013 39,836,032 RGD:9068941
G STIL STIL centriolar assembly protein JBrowse link 1 48,072,728 48,137,071 RGD:9068941
G TCP10L t-complex 10 like JBrowse link 21 32,320,569 32,331,667 RGD:9068941
G TEDC1 tubulin epsilon and delta complex 1 JBrowse link 14 105,916,696 105,925,911 RGD:9068941
G TEDC2 tubulin epsilon and delta complex 2 JBrowse link 16 2,559,493 2,564,370 RGD:9068941
G TOP2A DNA topoisomerase II alpha JBrowse link 17 17,097,619 17,127,195 RGD:9068941
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase JBrowse link 9 33,124,730 33,136,923 RGD:9068941
G TSGA10 testis specific 10 JBrowse link 2A 99,920,575 100,083,682 RGD:9068941
G TSKS testis specific serine kinase substrate JBrowse link 19 55,672,892 55,694,031 RGD:9068941
G TSSK2 testis specific serine kinase 2 JBrowse link 22 17,562,399 17,567,123 RGD:9068941
G TTBK2 tau tubulin kinase 2 JBrowse link 15 39,854,291 40,035,481 RGD:9068941
G TUBD1 tubulin delta 1 JBrowse link 17 58,766,864 58,798,842 RGD:9068941
G TUBG1 tubulin gamma 1 JBrowse link 17 14,925,451 14,931,340 RGD:9068941
G TUBGCP3 tubulin gamma complex associated protein 3 JBrowse link 13 112,702,519 112,801,429 RGD:9068941
G WDR62 WD repeat domain 62 JBrowse link 19 41,721,289 41,777,038 RGD:9068941
G WDR90 WD repeat domain 90 JBrowse link 16 664,407 682,221 RGD:9068941
G WRAP73 WD repeat containing, antisense to TP73 JBrowse link 1 3,425,648 3,443,952 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16551
    cellular anatomical entity 16421
      microtubule organizing center 757
        centriole 137
Path 2
Term Annotations click to browse term
  cellular_component 16551
    cellular anatomical entity 16421
      organelle 12648
        non-membrane-bounded organelle 4671
          intracellular non-membrane-bounded organelle 4662
            cytoskeleton 2122
              microtubule cytoskeleton 1202
                microtubule organizing center 757
                  centriole 137
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.