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ONTOLOGY REPORT - ANNOTATIONS


Term:eukaryotic translation initiation factor 2B complex
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Accession:GO:0005851 term browser browse the term
Definition:A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.
Synonyms:exact_synonym: eIF-2B;   eif2B


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eukaryotic translation initiation factor 2B complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha JBrowse link 12 37,444,136 37,452,391 RGD:1581073
RGD:13792537
RGD:1624291
RGD:1600115
RGD:11041878
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta JBrowse link 6 109,044,830 109,051,254 RGD:1581073
RGD:13792537
RGD:1624291
RGD:1600115
RGD:11041878
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma JBrowse link 5 135,882,946 135,949,276 RGD:1581073
RGD:13792537
RGD:1624291
RGD:1600115
RGD:11041878
RGD:1581075
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta JBrowse link 6 26,546,917 26,552,474 RGD:1581073
RGD:1624291
RGD:1600115
RGD:11041878
RGD:1581075
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 11 84,080,273 84,090,259 RGD:1581073
RGD:1581075
RGD:11041878
RGD:1600115
RGD:1624291
RGD:13792537
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 6 102,048,372 102,073,041 RGD:1600115
RGD:1624291
RGD:13792537

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Path 1
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  cellular_component 19843
    protein-containing complex 5779
      eukaryotic translation initiation factor 2B complex 6
Path 2
Term Annotations click to browse term
  cellular_component 19843
    intracellular 13806
      cytoplasm 10553
        eukaryotic translation initiation factor 2B complex 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.