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ONTOLOGY REPORT - ANNOTATIONS


Term:neurofilament
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Accession:GO:0005883 term browser browse the term
Definition:A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
Synonyms:exact_synonym: type IV intermediate filament
 xref: NIF_Subcellular:sao1316272517;   Wikipedia:Neurofilament


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neurofilament term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cldn11 claudin 11 JBrowse link 2 115,823,541 115,836,846 RGD:1624291
RGD:1600115
G Dlgap2 DLG associated protein 2 JBrowse link 16 79,872,238 80,596,977 RGD:8554678
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:12880030
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A JBrowse link 11 34,858,339 34,958,733 RGD:1624291
G Ina internexin neuronal intermediate filament protein, alpha JBrowse link 1 266,782,835 266,794,389 RGD:1624291
RGD:1600115
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:1624291
RGD:1600115
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:9743935
RGD:1624291
G Nefm neurofilament medium JBrowse link 15 44,855,307 44,860,604 RGD:9743935
RGD:1600115
RGD:1624291
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Pcp4 Purkinje cell protein 4 JBrowse link 11 36,851,035 36,912,272 RGD:9850249
G Prph peripherin JBrowse link 7 140,742,406 140,746,197 RGD:1624291
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:1624291
RGD:1600115

Term paths to the root
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  cellular_component 19951
    intracellular 13934
      cytoplasm 10687
        neurofilament 13
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        intracellular organelle 12137
          intracellular non-membrane-bounded organelle 4642
            cytoskeleton 2098
              intermediate filament cytoskeleton 193
                intermediate filament 156
                  neurofilament 13
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.