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ONTOLOGY REPORT - ANNOTATIONS


Term:insulin receptor complex
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Accession:GO:0005899 term browser browse the term
Definition:A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.


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insulin receptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:13792537
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1600115
RGD:1624291
RGD:15036814
RGD:13792537
G Insrr insulin receptor-related receptor JBrowse link 2 187,161,817 187,181,400 RGD:13792537
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:8554248
G Sorbs1 sorbin and SH3 domain containing 1 JBrowse link 1 259,373,921 259,502,108 RGD:1624291
RGD:11038810

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19949
    protein-containing complex 5829
      receptor complex 404
        plasma membrane signaling receptor complex 185
          insulin receptor complex 5
Path 2
Term Annotations click to browse term
  cellular_component 19949
    cellular anatomical entity 19598
      cell periphery 6304
        plasma membrane 6135
          plasma membrane protein complex 560
            plasma membrane signaling receptor complex 185
              insulin receptor complex 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.