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ONTOLOGY REPORT - ANNOTATIONS


Term:adherens junction
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Accession:GO:0005912 term browser browse the term
Definition:A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
Synonyms:exact_synonym: cell-cell adherens junction
 alt_id: GO:0005913
 xref: Wikipedia:Adherens_junction


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adherens junction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034767.1 RGD:13792537
G AABR07044900.1 RGD:1600115
G AABR07053516.1 RGD:1600115
G Abi2 abl-interactor 2 JBrowse link 9 67,234,612 67,284,504 RGD:1624291
G Actb actin, beta JBrowse link 12 13,715,843 13,718,813 RGD:1600115
RGD:1624291
G Adam10 ADAM metallopeptidase domain 10 JBrowse link 8 77,107,355 77,237,483 RGD:1624291
G Adam15 ADAM metallopeptidase domain 15 JBrowse link 2 188,661,831 188,672,337 RGD:1600115
G Add1 adducin 1 JBrowse link 14 81,367,466 81,426,610 RGD:1600115
RGD:1624291
RGD:13792537
G Afdn afadin, adherens junction formation factor JBrowse link 1 53,713,873 53,861,918 RGD:1299529
RGD:13792537
RGD:1624291
RGD:1600115
G Ahi1 Abelson helper integration site 1 JBrowse link 1 16,478,127 16,601,769 RGD:1624291
RGD:1600115
G Ajap1 adherens junctions associated protein 1 JBrowse link 5 170,615,885 170,679,315 RGD:1600115
RGD:1624291
RGD:13792537
G Ajuba ajuba LIM protein JBrowse link 15 33,208,210 33,218,456 RGD:13792537
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1600115
RGD:1624291
G Arhgap24 Rho GTPase activating protein 24 JBrowse link 14 8,383,211 8,600,526 RGD:1600115
G Arvcf ARVCF, delta catenin family member JBrowse link 11 86,736,125 86,793,795 RGD:13792537
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link 9 66,568,074 66,683,019 RGD:1600115
RGD:1624291
G Cd99l2 CD99 molecule-like 2 JBrowse link 15 5,265,257 5,311,232 RGD:1624291
G Cdc42ep4 CDC42 effector protein 4 JBrowse link 10 102,244,680 102,269,272 RGD:1600115
RGD:1624291
G Cdca3 cell division cycle associated 3 JBrowse link 4 157,347,876 157,351,889 RGD:1600115
RGD:1624291
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:1624291
RGD:13792537
G Cdh10 cadherin 10 JBrowse link 2 69,415,174 69,636,849 RGD:13792537
G Cdh11 cadherin 11 JBrowse link 19 2,391,181 2,551,245 RGD:13792537
G Cdh12 cadherin 12 JBrowse link 2 71,310,228 72,540,063 RGD:13792537
G Cdh13 cadherin 13 JBrowse link 19 50,848,793 51,971,618 RGD:13792537
G Cdh15 cadherin 15 JBrowse link 19 55,669,661 55,689,986 RGD:13792537
G Cdh17 cadherin 17 JBrowse link 5 25,354,187 25,443,675 RGD:13792537
G Cdh18 cadherin 18 JBrowse link 2 73,651,408 74,693,342 RGD:13792537
G Cdh19 cadherin 19 JBrowse link 13 32,344,954 32,469,887 RGD:13792537
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:1626295
RGD:1600115
RGD:1624291
RGD:13792537
RGD:2291902
G Cdh24 cadherin 24 JBrowse link 15 33,277,845 33,287,546 RGD:13792537
G Cdh26 cadherin 26 JBrowse link 3 173,969,004 174,020,867 RGD:13792537
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:13792537
RGD:1624291
G Cdh4 cadherin 4 JBrowse link 3 175,220,520 175,283,144 RGD:13792537
G Cdh5 cadherin 5 JBrowse link 19 1,025,122 1,074,333 RGD:1624291
RGD:13792537
G Cdh6 cadherin 6 JBrowse link 2 63,100,723 63,246,618 RGD:13792537
G Cdh7 cadherin 7 JBrowse link 13 31,081,064 31,228,884 RGD:13792537
G Cdh8 cadherin 8 JBrowse link 19 6,031,654 6,431,502 RGD:13792537
G Cdh9 cadherin 9 JBrowse link 2 66,938,796 67,078,897 RGD:13792537
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:2325151
G Crb1 crumbs cell polarity complex component 1 JBrowse link 13 56,270,519 56,462,893 RGD:1600115
RGD:1624291
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:2291902
RGD:1624291
G Ctnna2 catenin alpha 2 JBrowse link 4 107,880,611 109,042,724 RGD:1624291
G Ctnna3 catenin alpha 3 JBrowse link 20 25,063,124 26,640,428 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1626295
RGD:1600115
RGD:1624291
RGD:13792537
RGD:2291902
G Ctnnd1 catenin delta 1 JBrowse link 3 72,001,904 72,053,047 RGD:13792537
RGD:1624291
G Ctnnd2 catenin delta 2 JBrowse link 2 83,227,247 84,094,315 RGD:13792537
G Cxadr CXADR, Ig-like cell adhesion molecule JBrowse link 11 16,826,269 16,873,564 RGD:1600115
RGD:1624291
G Cyth1 cytohesin 1 JBrowse link 10 107,197,983 107,281,285 RGD:1600115
G Cyth2 cytohesin 2 JBrowse link 1 101,796,349 101,803,407 RGD:1600115
G Cyth3 cytohesin 3 JBrowse link 12 12,877,559 12,907,771 RGD:1600115
RGD:1624291
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:2314898
G Ddx6 DEAD-box helicase 6 JBrowse link 8 48,924,768 48,961,394 RGD:10755411
G Dlg5 discs large MAGUK scaffold protein 5 JBrowse link 15 120,213 230,312 RGD:1600115
RGD:1624291
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Dsc2 desmocollin 2 JBrowse link 18 11,826,705 11,858,801 RGD:1600115
RGD:1624291
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:8693712
G Efna5 ephrin A5 JBrowse link 9 110,054,002 110,329,878 RGD:1624291
RGD:1600115
G Efnb2 ephrin B2 JBrowse link 16 86,631,151 86,672,050 RGD:1624291
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 13 35,622,472 35,673,449 RGD:1600115
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:1624291
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:1624291
RGD:1600115
G Erbin erbb2 interacting protein JBrowse link 2 33,880,860 33,952,806 RGD:13792537
G Esam endothelial cell adhesion molecule JBrowse link 8 39,997,875 40,008,802 RGD:1624291
G Fat2 FAT atypical cadherin 2 JBrowse link 10 40,583,025 40,682,598 RGD:1600115
RGD:1624291
RGD:13792537
G Flot1 flotillin 1 JBrowse link 20 3,427,890 3,438,418 RGD:1600115
RGD:1624291
G Flot2 flotillin 2 JBrowse link 10 65,304,901 65,329,332 RGD:1600115
RGD:1624291
G Frmd4b FERM domain containing 4B JBrowse link 4 129,658,137 129,984,735 RGD:1624291
RGD:13792537
G Frmd5 FERM domain containing 5 JBrowse link 3 113,480,780 113,755,286 RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 7 60,128,506 60,210,482 RGD:1600115
RGD:1624291
G Itga6 integrin subunit alpha 6 JBrowse link 3 58,442,904 58,515,124 RGD:1600017
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:2325293
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1600115
RGD:1624291
G Jcad junctional cadherin 5 associated JBrowse link 17 55,667,754 55,709,738 RGD:1624291
RGD:13792537
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:2291902
RGD:1624291
RGD:13792537
G Keap1 Kelch-like ECH-associated protein 1 JBrowse link 8 22,250,518 22,259,868 RGD:2302250
G Klhl24 kelch-like family member 24 JBrowse link 11 84,613,101 84,643,674 RGD:1600115
RGD:1624291
G Lama3 laminin subunit alpha 3 JBrowse link 18 3,704,866 3,941,215 RGD:1600017
G Ldb3 LIM domain binding 3 JBrowse link 16 10,878,348 10,943,016 RGD:13792537
G Limd1 LIM domains containing 1 JBrowse link 8 132,553,218 132,598,826 RGD:1624291
RGD:13792537
RGD:1600115
G Lmo7 LIM domain 7 JBrowse link 15 86,242,911 86,458,512 RGD:1303994
G Lrrc7 leucine rich repeat containing 7 JBrowse link 2 264,910,594 265,300,860 RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:8693602
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 JBrowse link 4 125,684,816 126,300,013 RGD:1600115
RGD:1624291
G Mpp4 membrane palmitoylated protein 4 JBrowse link 9 65,917,917 65,961,274 RGD:1600115
RGD:1624291
G Mpp5 membrane palmitoylated protein 5 JBrowse link 6 101,923,675 102,029,705 RGD:1624291
RGD:1600115
G Mpp7 membrane palmitoylated protein 7 JBrowse link 17 60,057,077 60,250,303 RGD:1624291
G Mtss1 MTSS I-BAR domain containing 1 JBrowse link 7 98,820,799 98,960,878 RGD:1624291
G Myh9 myosin, heavy chain 9 JBrowse link 7 118,740,005 118,792,507 RGD:1624291
G Myo1e myosin IE JBrowse link 8 76,644,715 76,840,240 RGD:1624291
RGD:1600115
G Ndrg1 N-myc downstream regulated 1 JBrowse link 7 107,734,326 107,775,701 RGD:1600115
RGD:1624291
G Nectin1 nectin cell adhesion molecule 1 JBrowse link 8 48,094,233 48,198,499 RGD:13792537
RGD:1624291
G Nectin3 nectin cell adhesion molecule 3 JBrowse link 11 57,897,879 57,995,193 RGD:13792537
RGD:1624291
G Nectin4 nectin cell adhesion molecule 4 JBrowse link 13 89,755,665 89,774,185 RGD:13792537
RGD:1624291
G Nexn nexilin (F actin binding protein) JBrowse link 2 257,452,937 257,484,607 RGD:1600115
G Nf2 neurofibromin 2 JBrowse link 14 84,996,905 85,088,547 RGD:1624291
RGD:1600115
G Niban2 niban apoptosis regulator 2 JBrowse link 3 11,921,715 11,971,327 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:2303961
G Pard3 par-3 family cell polarity regulator JBrowse link 19 60,017,746 60,580,628 RGD:1624291
RGD:13792537
G Pard3b par-3 family cell polarity regulator beta JBrowse link 9 68,414,339 69,426,226 RGD:13792537
G Pdlim1 PDZ and LIM domain 1 JBrowse link 1 259,308,326 259,357,006 RGD:13792537
G Pdlim2 PDZ and LIM domain 2 JBrowse link 15 51,843,562 51,856,785 RGD:13792537
G Pdlim3 PDZ and LIM domain 3 JBrowse link 16 49,543,140 49,574,362 RGD:13792537
G Pdlim4 PDZ and LIM domain 4 JBrowse link 10 39,390,578 39,405,322 RGD:13792537
G Pdlim5 PDZ and LIM domain 5 JBrowse link 2 247,815,214 247,989,198 RGD:13792537
G Pdlim7 PDZ and LIM domain 7 JBrowse link 17 9,653,510 9,668,715 RGD:13792537
RGD:1624291
G Pgm5 phosphoglucomutase 5 JBrowse link 1 242,582,591 242,765,837 RGD:1624291
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma JBrowse link 7 11,267,207 11,294,291 RGD:1600115
G Pkp1 plakophilin 1 JBrowse link 13 52,705,174 52,753,089 RGD:13792537
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1581654
RGD:1624291
G Pkp3 plakophilin 3 JBrowse link 1 213,884,795 213,897,783 RGD:13792537
G Pkp4 plakophilin 4 JBrowse link 3 45,211,097 45,414,524 RGD:13792537
G Pof1b POF1B, actin binding protein JBrowse link X 84,099,618 84,167,717 RGD:1624291
G Ppp1ca protein phosphatase 1 catalytic subunit alpha JBrowse link 1 219,439,953 219,443,570 RGD:1600115
RGD:1624291
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B JBrowse link 10 82,800,704 82,816,735 RGD:1600115
G Prickle4 prickle planar cell polarity protein 4 JBrowse link 9 15,306,901 15,313,047 RGD:13792537
G Ptprm protein tyrosine phosphatase, receptor type, M JBrowse link 9 114,846,095 115,555,261 RGD:1600115
RGD:1624291
G Pvr PVR cell adhesion molecule JBrowse link 1 80,820,306 80,835,712 RGD:13792537
G Rdx radixin JBrowse link 8 56,570,728 56,612,851 RGD:8693627
G Rnd1 Rho family GTPase 1 JBrowse link 7 140,349,138 140,356,209 RGD:1624291
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:13792537
RGD:1624291
G Sdcbp syndecan binding protein JBrowse link 5 19,471,664 19,498,499 RGD:1600115
G Sh3bp1 SH3-domain binding protein 1 JBrowse link 7 120,125,747 120,138,148 RGD:1624291
RGD:1600115
G Shroom1 shroom family member 1 JBrowse link 10 38,814,420 38,825,159 RGD:13792537
G Shroom2 shroom family member 2 JBrowse link X 23,478,869 23,649,424 RGD:13792537
RGD:1624291
G Shroom3 shroom family member 3 JBrowse link 14 16,622,767 16,903,265 RGD:1624291
RGD:13792537
G Shroom4 shroom family member 4 JBrowse link X 16,723,360 16,929,829 RGD:13792537
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Snap23 synaptosome associated protein 23 JBrowse link 3 112,333,972 112,362,960 RGD:1624291
G Sorbs1 sorbin and SH3 domain containing 1 JBrowse link 1 259,373,921 259,502,108 RGD:1600115
RGD:1624291
G Sptbn4 spectrin, beta, non-erythrocytic 4 JBrowse link 1 84,168,494 84,254,679 RGD:1624291
G Ssx2ip SSX family member 2 interacting protein JBrowse link 2 252,263,323 252,296,049 RGD:629551
RGD:1600115
G Tbcd tubulin folding cofactor D JBrowse link 10 110,643,693 110,800,493 RGD:13792537
G Tgm1 transglutaminase 1 JBrowse link 15 34,378,136 34,393,150 RGD:1624291
G Tjp1 tight junction protein 1 JBrowse link 1 126,146,489 126,515,359 RGD:1624291
G Tln1 talin 1 JBrowse link 5 59,033,635 59,063,592 RGD:1624291
RGD:1600115
G Tmem204 transmembrane protein 204 JBrowse link 10 14,417,608 14,446,272 RGD:1600115
G Tnk2 tyrosine kinase, non-receptor, 2 JBrowse link 11 71,348,726 71,388,520 RGD:1600115
G Tnks1bp1 tankyrase 1 binding protein 1 JBrowse link 3 72,458,520 72,483,206 RGD:1600115
RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
G Vcl vinculin JBrowse link 15 3,455,211 3,544,738 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Vezt vezatin, adherens junctions transmembrane protein JBrowse link 7 34,888,487 34,951,712 RGD:1600115
G Wnk3 WNK lysine deficient protein kinase 3 JBrowse link X 20,316,081 20,459,245 RGD:1624291
G Xirp1 xin actin-binding repeat containing 1 JBrowse link 8 128,694,809 128,712,092 RGD:1624291
G Zyx zyxin JBrowse link 4 71,740,188 71,749,386 RGD:1600115
RGD:1624291
MPP7-DLG1-LIN7 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
RGD:1600115
G Lin7a lin-7 homolog A, crumbs cell polarity complex component JBrowse link 7 49,429,613 49,627,835 RGD:1600115
RGD:13792537
G Lin7b lin-7 homolog B, crumbs cell polarity complex component JBrowse link 1 101,358,313 101,361,439 RGD:13792537
G Lin7c lin-7 homolog C, crumbs cell polarity complex component JBrowse link 3 101,010,923 101,018,235 RGD:1624291
RGD:13792537
G Mpp7 membrane palmitoylated protein 7 JBrowse link 17 60,057,077 60,250,303 RGD:1624291
spot adherens junction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pgm5 phosphoglucomutase 5 JBrowse link 1 242,582,591 242,765,837 RGD:1624291
RGD:13792537
zonula adherens term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn1 actinin, alpha 1 JBrowse link 6 103,376,557 103,470,497 RGD:1600115
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 JBrowse link 12 2,133,935 2,157,403 RGD:1624291
RGD:1600115
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:1624291
G Ctnnd1 catenin delta 1 JBrowse link 3 72,001,904 72,053,047 RGD:2316209
G Kifc3 kinesin family member C3 JBrowse link 19 10,305,405 10,339,186 RGD:1624291
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:1624291
G Plekha7 pleckstrin homology domain containing A7 JBrowse link 1 185,427,600 185,493,985 RGD:1624291
G Vcl vinculin JBrowse link 15 3,455,211 3,544,738 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19737
    cellular anatomical entity 19353
      cell junction 1115
        anchoring junction 651
          cell-cell junction 517
            adherens junction 155
              MPP7-DLG1-LIN7 complex 5
              spot adherens junction 1
              zonula adherens + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.