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ONTOLOGY REPORT - ANNOTATIONS


Term:adherens junction
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Accession:GO:0005912 term browser browse the term
Definition:A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
Synonyms:exact_synonym: cell-cell adherens junction
 alt_id: GO:0005913
 xref: Wikipedia:Adherens_junction


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adherens junction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADD1 adducin 1 JBrowse link 3 61,356,643 61,443,851 RGD:13508589
G AFDN afadin, adherens junction formation factor JBrowse link 1 55,435,451 55,535,534 RGD:13508589
G AHI1 Abelson helper integration site 1 JBrowse link 1 27,966,101 28,199,163 RGD:13508589
G AJAP1 adherens junctions associated protein 1 JBrowse link 5 58,907,970 59,023,115 RGD:13508589
G AJUBA ajuba LIM protein JBrowse link 8 3,272,408 3,302,179 RGD:13508589
G ARVCF ARVCF delta catenin family member JBrowse link 26 29,304,710 29,359,110 RGD:13508589
G BMPR2 bone morphogenetic protein receptor type 2 JBrowse link 37 11,342,292 11,540,199 RGD:13508589
G CD99L2 CD99 molecule like 2 JBrowse link X 119,000,342 119,041,859 RGD:13508589
G CDC42EP4 CDC42 effector protein 4 JBrowse link 9 6,888,183 6,909,986 RGD:13508589
G CDCA3 cell division cycle associated 3 JBrowse link 27 38,172,717 38,174,963 RGD:13508589
G CDH1 cadherin 1 JBrowse link 5 80,757,508 80,834,878 RGD:13508589
G CDH10 cadherin 10 JBrowse link 4 80,927,251 81,101,053 RGD:13508589
G CDH11 cadherin 11 JBrowse link 5 83,977,267 84,122,712 RGD:13508589
G CDH12 cadherin 12 JBrowse link 4 82,501,335 83,124,378 RGD:13508589
G CDH13 cadherin 13 JBrowse link 5 68,491,156 69,586,119 RGD:13508589
G CDH15 cadherin 15 JBrowse link 5 64,258,451 64,277,184 RGD:13508589
G CDH17 cadherin 17 JBrowse link 29 38,918,098 38,980,709 RGD:13508589
G CDH18 cadherin 18 JBrowse link 4 83,915,145 84,873,581 RGD:13508589
G CDH19 cadherin 19 JBrowse link 1 11,074,216 11,168,816 RGD:13508589
G CDH2 cadherin 2 JBrowse link 7 60,736,760 60,950,477 RGD:13508589
G CDH23 cadherin related 23 JBrowse link 4 22,206,972 22,570,875 RGD:13508589
G CDH24 cadherin 24 JBrowse link 8 3,359,452 3,369,590 RGD:13508589
G CDH26 cadherin 26 JBrowse link 24 44,566,610 44,608,670 RGD:13508589
G CDH3 cadherin 3 JBrowse link 5 80,864,859 80,912,136 RGD:13508589
G CDH4 cadherin 4 JBrowse link 24 45,749,589 46,063,960 RGD:13508589
G CDH5 cadherin 5 JBrowse link 5 82,830,505 82,863,931 RGD:13508589
G CDH6 cadherin 6 JBrowse link 4 75,950,999 75,999,250 RGD:13508589
G CDH7 cadherin 7 JBrowse link 1 11,699,505 11,824,489 RGD:13508589
G CDH8 cadherin 8 JBrowse link 5 86,402,078 86,743,563 RGD:13508589
G CDH9 cadherin 9 JBrowse link 4 79,153,276 79,284,514 RGD:13508589
G CDHR1 cadherin related family member 1 JBrowse link 4 32,435,364 32,459,181 RGD:13508589
G CRB1 crumbs cell polarity complex component 1 JBrowse link 7 5,277,394 5,490,542 RGD:13508589
G CTNNA3 catenin alpha 3 JBrowse link 4 17,364,121 19,035,836 RGD:13508589
G CTNNB1 catenin beta 1 JBrowse link 23 10,559,722 10,572,933 RGD:13508589
G CTNND2 catenin delta 2 JBrowse link 34 2,521,730 3,438,218 RGD:13508589
G CXADR CXADR Ig-like cell adhesion molecule JBrowse link 31 14,021,292 14,079,049 RGD:13508589
G CYTH3 cytohesin 3 JBrowse link 6 11,554,922 11,653,201 RGD:13508589
G DLL1 delta like canonical Notch ligand 1 JBrowse link 12 72,265,078 72,272,347 RGD:13508589
G DSC2 desmocollin 2 JBrowse link 7 58,369,316 58,402,028 RGD:13508589
G EFNA5 ephrin A5 JBrowse link 3 4,272,138 4,546,527 RGD:13508589
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 19 29,916,994 30,063,243 RGD:13508589
G EPHA5 EPH receptor A5 JBrowse link 13 56,054,247 56,402,583 RGD:13508589
G ESAM endothelial cell adhesion molecule JBrowse link 5 9,658,920 9,667,134 RGD:13508589
G FAM120C family with sequence similarity 120C JBrowse link X 45,780,015 45,943,571 RGD:13508589
G FAT2 FAT atypical cadherin 2 JBrowse link 4 57,743,007 57,823,740 RGD:13508589
G FLOT1 flotillin 1 JBrowse link 12 517,941 528,677 RGD:13508589
G FRMD4A FERM domain containing 4A JBrowse link 2 22,128,030 22,857,707 RGD:13508589
G FRMD4B FERM domain containing 4B JBrowse link 20 22,253,619 22,574,917 RGD:13508589
G FRMD5 FERM domain containing 5 JBrowse link 30 10,611,986 10,923,444 RGD:13508589
G FRS2 fibroblast growth factor receptor substrate 2 JBrowse link 10 11,445,843 11,552,325 RGD:13508589
G IGSF21 immunoglobin superfamily member 21 JBrowse link 2 80,114,962 80,355,204 RGD:13508589
G JAG1 jagged canonical Notch ligand 1 JBrowse link 24 11,656,926 11,693,146 RGD:13508589
G JCAD junctional cadherin 5 associated JBrowse link 2 16,453,739 16,529,023 RGD:13508589
G JUP junction plakoglobin JBrowse link 9 21,028,773 21,053,071 RGD:13508589
G KLHL24 kelch like family member 24 JBrowse link 34 16,583,683 16,625,778 RGD:13508589
G LDB3 LIM domain binding 3 JBrowse link 4 34,367,155 34,421,992 RGD:13508589
G LIMD1 LIM domains containing 1 JBrowse link 20 42,797,316 42,867,292 RGD:13508589
G LOC100855871 plakophilin-1 JBrowse link 7 1,530,345 1,576,113 RGD:13508589
G LOC489647 cadherin-1-like JBrowse link 5 63,571,991 63,589,031 RGD:13508589
G LRRC7 leucine rich repeat containing 7 JBrowse link 6 75,578,651 75,964,171 RGD:13508589
G MPP5 membrane palmitoylated protein 5 JBrowse link 8 41,230,230 41,330,017 RGD:13508589
G MYO1E myosin IE JBrowse link 30 24,067,622 24,265,567 RGD:13508589
G NDRG1 N-myc downstream regulated 1 JBrowse link 13 29,689,294 29,745,964 RGD:13508589
G NECTIN1 nectin cell adhesion molecule 1 JBrowse link 5 14,228,197 14,292,825 RGD:13508589
G NECTIN3 nectin cell adhesion molecule 3 JBrowse link 33 15,868,813 16,173,158 RGD:13508589
G NECTIN4 nectin cell adhesion molecule 4 JBrowse link 38 21,378,144 21,392,419 RGD:13508589
G NF2 neurofibromin 2 JBrowse link 26 22,816,869 22,896,103 RGD:13508589
G NIBAN2 niban apoptosis regulator 2 JBrowse link 9 55,802,010 55,853,960 RGD:13508589
G NOTCH1 notch receptor 1 JBrowse link 9 48,975,972 49,018,985 RGD:13508589
G NPHP1 nephrocystin 1 JBrowse link 17 35,076,527 35,136,674 RGD:13508589
G PARD3 par-3 family cell polarity regulator JBrowse link 2 2,252,262 2,791,459 RGD:13508589
G PARD3B par-3 family cell polarity regulator beta JBrowse link 37 13,251,965 14,233,893 RGD:13508589
G PDLIM1 PDZ and LIM domain 1 JBrowse link 28 8,770,882 8,817,828 RGD:13508589
G PDLIM2 PDZ and LIM domain 2 JBrowse link 25 34,684,954 34,699,144 RGD:13508589
G PDLIM3 PDZ and LIM domain 3 JBrowse link 16 45,111,358 45,141,444 RGD:13508589
G PDLIM4 PDZ and LIM domain 4 JBrowse link 11 20,570,839 20,587,185 RGD:13508589
G PDLIM5 PDZ and LIM domain 5 JBrowse link 32 17,294,023 17,505,212 RGD:13508589
G PHF8 PHD finger protein 8 JBrowse link X 45,635,204 45,741,850 RGD:13508589
G PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) JBrowse link 7 1,921,143 1,966,910 RGD:13508589
G PKP2 plakophilin 2 JBrowse link 27 16,023,186 16,109,978 RGD:13508589
G PKP3 plakophilin 3 JBrowse link 18 25,540,073 25,547,667 RGD:13508589
G PKP4 plakophilin 4 JBrowse link 36 4,342,715 4,575,672 RGD:13508589
G PPP1CA protein phosphatase 1 catalytic subunit alpha JBrowse link 18 50,062,352 50,065,166 RGD:13508589
G PRICKLE4 prickle planar cell polarity protein 4 JBrowse link 12 10,466,393 10,473,555 RGD:13508589
G PTPRM protein tyrosine phosphatase receptor type M JBrowse link 7 74,005,682 74,597,498 RGD:13508589
G PVR PVR cell adhesion molecule JBrowse link 1 110,692,906 110,713,209 RGD:13508589
G RND1 Rho family GTPase 1 JBrowse link 27 5,679,629 5,686,657 RGD:13508589
G SCRIB scribble planar cell polarity protein JBrowse link 13 37,356,405 37,374,765 RGD:13508589
G SHROOM1 shroom family member 1 JBrowse link 11 21,115,103 21,120,934 RGD:13508589
G SHROOM2 shroom family member 2 JBrowse link X 6,499,570 6,642,738 RGD:13508589
G SHROOM3 shroom family member 3 JBrowse link 32 1,218,513 1,392,014 RGD:13508589
G SHROOM4 shroom family member 4 JBrowse link X 43,366,921 43,639,525 RGD:13508589
G SMAD7 SMAD family member 7 JBrowse link 7 79,706,485 79,734,673 RGD:13508589
G SNAP23 synaptosome associated protein 23 JBrowse link 30 9,453,931 9,493,506 RGD:13508589
G TBCD tubulin folding cofactor D RGD:13508589
G TLN1 talin 1 JBrowse link 11 52,227,286 52,260,112 RGD:13508589
G TMEM47 transmembrane protein 47 JBrowse link X 29,675,386 29,705,941 RGD:13508589
G TNKS1BP1 tankyrase 1 binding protein 1 JBrowse link 18 38,815,845 38,838,184 RGD:13508589
G VCL vinculin JBrowse link 4 24,404,279 24,518,977 RGD:13508589
G WNK3 WNK lysine deficient protein kinase 3 JBrowse link X 45,951,049 46,111,643 RGD:13508589
G ZYX zyxin RGD:13508589
MPP7-DLG1-LIN7 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LIN7A lin-7 homolog A, crumbs cell polarity complex component JBrowse link 15 23,101,524 23,186,343 RGD:13508589
G LIN7B lin-7 homolog B, crumbs cell polarity complex component JBrowse link 1 107,332,623 107,336,099 RGD:13508589
G LIN7C lin-7 homolog C, crumbs cell polarity complex component JBrowse link 21 48,061,446 48,071,458 RGD:13508589
spot adherens junction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PGM5 phosphoglucomutase 5 JBrowse link 1 88,823,883 89,011,091 RGD:13508589
zonula adherens term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTN1 actinin alpha 1 JBrowse link 8 42,714,806 42,808,318 RGD:13508589
G CTNNA1 catenin alpha 1 JBrowse link 11 26,273,322 26,459,497 RGD:13508589
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 1 110,543,140 110,569,168 RGD:13508589
G VCL vinculin JBrowse link 4 24,404,279 24,518,977 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 13849
    cellular anatomical entity 13706
      cell junction 516
        anchoring junction 398
          cell-cell junction 311
            adherens junction 108
              MPP7-DLG1-LIN7 complex 3
              spot adherens junction 1
              zonula adherens + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.