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ONTOLOGY REPORT - ANNOTATIONS


Term:cAMP-dependent protein kinase complex
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Accession:GO:0005952 term browser browse the term
Definition:An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
Synonyms:exact_synonym: 3',5' cAMP-dependent protein kinase complex;   adenosine 3',5'-cyclophosphate-dependent protein kinase complex;   cyclic AMP-dependent protein kinase complex
 related_synonym: PKA


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cAMP-dependent protein kinase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKAP14 A-kinase anchoring protein 14 JBrowse link X 119,895,893 119,920,716 RGD:2290271
G AKAP4 A-kinase anchoring protein 4 JBrowse link X 50,190,777 50,201,007 RGD:2290271
G PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 JBrowse link 1 147,155,106 147,173,366 RGD:9068941
G PRKACA protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 14,091,688 14,117,762 RGD:2290271
G PRKACB protein kinase cAMP-activated catalytic subunit beta JBrowse link 1 84,077,975 84,238,498 RGD:2290271
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 17 68,413,623 68,551,316 RGD:2290271
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta JBrowse link 7 549,185 727,676 RGD:2290271
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha JBrowse link 3 48,744,601 48,847,874 RGD:2290271
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 7 107,044,705 107,161,811 RGD:2290271
G PRKX protein kinase X-linked JBrowse link X 3,604,340 3,713,649 RGD:2290271
G PRKY protein kinase Y-linked (pseudogene) JBrowse link Y 7,273,972 7,381,547 RGD:2290271

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  cellular_component 19245
    protein-containing complex 5868
      cAMP-dependent protein kinase complex 11
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.