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ONTOLOGY REPORT - ANNOTATIONS


Term:cAMP-dependent protein kinase complex
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Accession:GO:0005952 term browser browse the term
Definition:An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
Synonyms:exact_synonym: 3',5' cAMP-dependent protein kinase complex;   adenosine 3',5'-cyclophosphate-dependent protein kinase complex;   cyclic AMP-dependent protein kinase complex
 related_synonym: PKA


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cAMP-dependent protein kinase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKAP14 A-kinase anchoring protein 14 JBrowse link X 98,234,469 98,255,396 RGD:9068941
G PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 JBrowse link 4 100,378,047 100,394,346 RGD:9068941
G PRKACA protein kinase cAMP-activated catalytic subunit alpha JBrowse link 2 65,074,876 65,095,564 RGD:14298760
G PRKACB protein kinase cAMP-activated catalytic subunit beta JBrowse link 6 129,520,397 129,636,207 RGD:9068941
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 12 11,662,344 11,681,490 RGD:14298760
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta JBrowse link 3 343,124 425,154 RGD:14298760
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha JBrowse link 13 31,427,786 31,517,005 RGD:14298760
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 9 106,851,044 106,957,519 RGD:14298760
G PRKX protein kinase X-linked JBrowse link X 657,421 753,739 RGD:14298760

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  cellular_component 16660
    protein-containing complex 4952
      cAMP-dependent protein kinase complex 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.