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ONTOLOGY REPORT - ANNOTATIONS


Term:acetyl-CoA biosynthetic process
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Accession:GO:0006085 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
Synonyms:exact_synonym: acetyl-CoA anabolism;   acetyl-CoA biosynthesis;   acetyl-CoA formation;   acetyl-CoA synthesis
 xref: MetaCyc:PWY-5173


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acetyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
G Acly ATP citrate lyase JBrowse link 10 88,392,248 88,442,845 RGD:631761
RGD:13792537
RGD:1600115
RGD:1624291
G Acss1 acyl-CoA synthetase short-chain family member 1 JBrowse link 3 146,420,346 146,470,293 RGD:1624291
G Acss2 acyl-CoA synthetase short-chain family member 2 JBrowse link 3 151,032,925 151,075,856 RGD:1624291
G Mlycd malonyl-CoA decarboxylase JBrowse link 19 52,032,950 52,048,773 RGD:1600790
RGD:13792537
RGD:1624291
RGD:1600115
G Ppcs phosphopantothenoylcysteine synthetase JBrowse link 5 138,466,298 138,470,108 RGD:1624291
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acss1 acyl-CoA synthetase short-chain family member 1 JBrowse link 3 146,420,346 146,470,293 RGD:1600115
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlat dihydrolipoamide S-acetyltransferase JBrowse link 8 55,062,549 55,087,832 RGD:1599112
G Dld dihydrolipoamide dehydrogenase JBrowse link 6 50,597,677 50,618,694 RGD:1599112
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 JBrowse link 16 88,344,440 88,347,335 RGD:1600115
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 JBrowse link 2 246,736,449 246,737,997 RGD:1599112
RGD:13792537
G Pdhb pyruvate dehydrogenase E1 subunit beta JBrowse link 15 18,540,826 18,546,855 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdhx pyruvate dehydrogenase complex, component X JBrowse link 3 92,910,300 92,933,725 RGD:1600115
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:729541
mitochondrial acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpc1 mitochondrial pyruvate carrier 1 JBrowse link 1 53,026,608 53,038,229 RGD:1624291
G Mpc2 mitochondrial pyruvate carrier 2 JBrowse link 13 83,680,527 83,700,491 RGD:1624291
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1624291
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdk1 pyruvate dehydrogenase kinase 1 JBrowse link 3 58,530,870 58,561,494 RGD:1600115
RGD:1624291
G Pdk2 pyruvate dehydrogenase kinase 2 JBrowse link 10 82,838,270 82,852,758 RGD:1600115
RGD:1624291
G Pdk3 pyruvate dehydrogenase kinase 3 JBrowse link X 62,836,131 62,904,114 RGD:1624291
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      organic substance metabolic process 10949
        thioester metabolic process 88
          acyl-CoA metabolic process 88
            acetyl-CoA metabolic process 37
              acetyl-CoA biosynthetic process 19
                acetyl-CoA biosynthetic process from acetate 1
                acetyl-CoA biosynthetic process from ethanol 0
                acetyl-CoA biosynthetic process from pantothenate 0
                acetyl-CoA biosynthetic process from pyruvate + 13
                carbon fixation by acetyl-CoA pathway 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      cellular metabolic process 10567
        cellular aromatic compound metabolic process 5484
          nucleobase-containing compound metabolic process 5258
            nucleobase-containing small molecule metabolic process 575
              nucleoside phosphate metabolic process 496
                nucleotide metabolic process 489
                  ribonucleotide metabolic process 392
                    purine ribonucleotide metabolic process 377
                      purine ribonucleotide biosynthetic process 165
                        acyl-CoA biosynthetic process 34
                          acetyl-CoA biosynthetic process 19
                            acetyl-CoA biosynthetic process from acetate 1
                            acetyl-CoA biosynthetic process from ethanol 0
                            acetyl-CoA biosynthetic process from pantothenate 0
                            acetyl-CoA biosynthetic process from pyruvate + 13
                            carbon fixation by acetyl-CoA pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.