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ONTOLOGY REPORT - ANNOTATIONS


Term:lactate metabolic process
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Accession:GO:0006089 term browser browse the term
Definition:The chemical reactions and pathways involving lactate, the anion of lactic acid.
Synonyms:exact_synonym: 2-hydroxypropanoate metabolic process;   2-hydroxypropanoate metabolism;   alpha-hydroxypropionate metabolic process;   alpha-hydroxypropionate metabolism;   lactate metabolism


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lactate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Ldha lactate dehydrogenase A JBrowse link 1 102,900,288 102,909,713 RGD:1624966
G Ldhb lactate dehydrogenase B JBrowse link 4 176,701,980 176,719,999 RGD:1624966
G Mrs2 magnesium transporter MRS2 JBrowse link 17 42,064,271 42,083,602 RGD:12793070
G Mtch2 mitochondrial carrier 2 JBrowse link 3 79,678,141 79,695,356 RGD:1624291
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 JBrowse link 13 47,413,453 47,440,682 RGD:2304071
G Slc37a4 solute carrier family 37 member 4 JBrowse link 8 48,716,914 48,723,024 RGD:1624291
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ldha lactate dehydrogenase A JBrowse link 1 102,900,288 102,909,713 RGD:1624291
lactate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
G Per2 period circadian regulator 2 JBrowse link 9 98,555,154 98,597,362 RGD:1624291
RGD:1600115
lactate biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:1624291
G Ldhc lactate dehydrogenase C JBrowse link 1 102,914,875 102,931,843 RGD:1624291
RGD:1600115
lactate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ldhd lactate dehydrogenase D JBrowse link 19 43,826,989 43,848,937 RGD:1624291
RGD:13792537
lactate oxidation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Carns1 carnosine synthase 1 JBrowse link 1 219,413,897 219,424,533 RGD:13792537
G Hao1 hydroxyacid oxidase 1 JBrowse link 3 127,444,900 127,500,709 RGD:13792537
G Hao2 hydroxyacid oxidase 2 JBrowse link 2 200,785,492 200,808,868 RGD:13792537
G Ldhc lactate dehydrogenase C JBrowse link 1 102,914,875 102,931,843 RGD:1624291
RGD:1600115
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hagh hydroxyacyl glutathione hydrolase JBrowse link 10 14,215,913 14,230,506 RGD:1600115
G Haghl hydroxyacylglutathione hydrolase-like JBrowse link 10 15,152,736 15,157,221 RGD:1600115
G Pnkd PNKD metallo-beta-lactamase domain containing JBrowse link 9 81,566,074 81,634,531 RGD:1600115
methylglyoxal catabolic process to lactate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1600115
RGD:1624291
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc25a12 solute carrier family 25 member 12 JBrowse link 3 57,881,951 57,998,214 RGD:13628741
G Tigar TP53 induced glycolysis regulatory phosphatase JBrowse link 4 159,635,145 159,654,108 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
protein deglycation, methylglyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      organic substance metabolic process 11297
        organic hydroxy compound metabolic process 535
          lactate metabolic process 23
            L-threonine catabolic process to D-lactate 0
            glucose catabolic process to lactate + 5
            lactate biosynthetic process + 5
            lactate catabolic process + 1
            lactate oxidation 4
            lactate racemization 0
            methylglyoxal catabolic process to lactate + 4
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      cellular metabolic process 10737
        organic acid metabolic process 1053
          oxoacid metabolic process 1026
            carboxylic acid metabolic process 979
              monocarboxylic acid metabolic process 642
                lactate metabolic process 23
                  L-threonine catabolic process to D-lactate 0
                  glucose catabolic process to lactate + 5
                  lactate biosynthetic process + 5
                  lactate catabolic process + 1
                  lactate oxidation 4
                  lactate racemization 0
                  methylglyoxal catabolic process to lactate + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.