Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:pyruvate metabolic process
go back to main search page
Accession:GO:0006090 term browser browse the term
Definition:The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
Synonyms:exact_synonym: pyruvate metabolism
 related_synonym: pyruvate dehydrogenase bypass
 alt_id: GO:0006087
 xref: MetaCyc:P41-PWY;   Wikipedia:Pyruvic_acid


show annotations for term's descendants       view all columns           Sort by:
 
pyruvate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kyat1 kynurenine aminotransferase 1 JBrowse link 3 8,752,289 8,785,617 RGD:9685040
G Ldhc lactate dehydrogenase C JBrowse link 1 102,914,875 102,931,843 RGD:1624291
G Me1 malic enzyme 1 JBrowse link 8 94,256,830 94,368,834 RGD:13792537
G Me2 malic enzyme 2 JBrowse link 18 69,737,515 69,784,099 RGD:13792537
G Me3 malic enzyme 3 JBrowse link 1 153,861,535 154,058,608 RGD:1624291
RGD:13792537
G Pc pyruvate carboxylase JBrowse link 1 219,759,157 219,859,854 RGD:1601554
RGD:13792537
RGD:1600115
RGD:2302972
RGD:2302971
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:13792537
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) JBrowse link 15 34,216,735 34,224,357 RGD:7242950
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 JBrowse link 2 246,736,449 246,737,997 RGD:1624291
RGD:1600115
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 JBrowse link 13 47,413,453 47,440,682 RGD:2304071
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlat dihydrolipoamide S-acetyltransferase JBrowse link 8 55,062,549 55,087,832 RGD:1599112
RGD:13792537
G Dld dihydrolipoamide dehydrogenase JBrowse link 6 50,597,677 50,618,694 RGD:1599112
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 JBrowse link 16 88,344,440 88,347,335 RGD:1600115
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 JBrowse link 2 246,736,449 246,737,997 RGD:1599112
RGD:13792537
G Pdhb pyruvate dehydrogenase E1 subunit beta JBrowse link 15 18,540,826 18,546,855 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdhx pyruvate dehydrogenase complex, component X JBrowse link 3 92,910,300 92,933,725 RGD:1600115
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:729541
canonical glycolysis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eno1 enolase 1 JBrowse link 5 167,288,223 167,299,610 RGD:2302788
RGD:1624291
G Eno2 enolase 2 JBrowse link 4 157,285,192 157,294,090 RGD:2302788
G Foxk1 forkhead box K1 JBrowse link 12 14,183,436 14,244,634 RGD:1624291
G Foxk2 forkhead box K2 JBrowse link 10 110,468,905 110,518,854 RGD:1624291
G LOC100911625 gamma-enolase-like JBrowse link 9 20,251,564 20,260,465 RGD:2302788
G Pfkl phosphofructokinase, liver type JBrowse link 20 11,393,860 11,415,889 RGD:13792537
G Pfkm phosphofructokinase, muscle JBrowse link 7 139,702,066 139,722,132 RGD:1624291
RGD:13792537
RGD:1600115
G Pfkp phosphofructokinase, platelet JBrowse link 17 68,510,765 68,574,387 RGD:13792537
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:8553288
RGD:13792537
RGD:1624291
glycolysis from storage polysaccharide through glucose-1-phosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pfkm phosphofructokinase, muscle JBrowse link 7 139,702,066 139,722,132 RGD:1624291
RGD:1600115
glycolytic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07005667.1 RGD:13792537
G AABR07006451.1 RGD:13792537
G AABR07013200.1 RGD:13792537
G AABR07021086.1 RGD:13792537
G AABR07022022.1 RGD:13792537
G AABR07024795.1 RGD:13792537
G AABR07025010.1 RGD:1600115
G AABR07028748.1 RGD:13792537
G AABR07029675.1 RGD:1600115
G AABR07030729.1 RGD:1600115
RGD:13792537
G AABR07032392.1 RGD:1600115
G AABR07034445.1 RGD:1600115
RGD:13792537
G AABR07040494.1 RGD:1600115
G AABR07040565.1 RGD:13792537
G AABR07041179.1 RGD:13792537
G AABR07045032.1 RGD:1600115
RGD:13792537
G AABR07052523.1 RGD:1600115
G AABR07053879.1 RGD:1600115
RGD:13792537
G AABR07066994.1 RGD:13792537
G AABR07067976.1 RGD:1600115
G AABR07068417.1 RGD:13792537
G AABR07070043.1 RGD:1600115
RGD:13792537
G AABR07071101.1 RGD:13792537
G AC094212.1 RGD:1600115
RGD:13792537
G AC107446.2 RGD:13792537
G AC110474.1 RGD:1600115
G AC110981.1 RGD:13792537
G Aldoa aldolase, fructose-bisphosphate A JBrowse link 1 198,228,387 198,233,988 RGD:1600115
RGD:13792537
RGD:1624291
G Aldoart2 aldolase 1 A retrogene 2 JBrowse link 6 76,349,362 76,351,052 RGD:1600115
RGD:13792537
G Aldob aldolase, fructose-bisphosphate B JBrowse link 5 64,805,772 64,818,813 RGD:2302804
RGD:13792537
RGD:1600115
RGD:1624291
G Aldoc aldolase, fructose-bisphosphate C JBrowse link 10 65,586,504 65,590,093 RGD:1600115
RGD:13792537
G Bpgm bisphosphoglycerate mutase JBrowse link 4 61,912,210 61,940,697 RGD:1600115
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 JBrowse link 17 76,306,585 76,358,058 RGD:1600115
G Eno1 enolase 1 JBrowse link 5 167,288,223 167,299,610 RGD:12792993
G Eno1-ps1 enolase 1, (alpha), pseudogene 1 JBrowse link 3 59,408,531 59,410,209 RGD:1600115
G Eno2 enolase 2 JBrowse link 4 157,285,192 157,294,090 RGD:2302804
G Eno3 enolase 3 JBrowse link 10 57,278,271 57,283,661 RGD:1600115
G Eno4 enolase 4 JBrowse link 1 280,097,061 280,129,750 RGD:1624291
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link 4 157,676,336 157,680,322 RGD:2302804
RGD:13792537
RGD:13792662
RGD:1600115
G Gapdh-ps2 glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2 JBrowse link 16 25,773,573 25,774,863 RGD:1600115
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic JBrowse link 1 89,180,063 89,195,347 RGD:1303349
RGD:13792537
RGD:1624291
RGD:1600115
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:2302790
RGD:1600115
RGD:13792537
RGD:2302851
G Gpi glucose-6-phosphate isomerase JBrowse link 1 90,063,411 90,091,287 RGD:1600115
RGD:13792537
RGD:1624291
G Hk1 hexokinase 1 JBrowse link 20 31,911,460 31,979,780 RGD:1358232
RGD:1600115
RGD:13792537
RGD:2302851
RGD:2302804
G Hk2 hexokinase 2 JBrowse link 4 113,559,396 113,609,897 RGD:13792537
RGD:1600115
G Hk3 hexokinase 3 JBrowse link 17 10,134,726 10,152,976 RGD:13792537
RGD:1600115
G LOC100362738 M2 pyruvate kinase-like JBrowse link 20 18,058,221 18,060,409 RGD:1600115
RGD:13792537
G LOC100911515 triosephosphate isomerase-like JBrowse link 9 20,213,596 20,217,279 RGD:1600115
G LOC103693780 2-oxoglutarate dehydrogenase, mitochondrial-like JBrowse link 14 86,599,906 86,614,963 RGD:1600115
G LOC108351137 glyceraldehyde-3-phosphate dehydrogenase JBrowse link 5 115,649,077 115,650,141 RGD:1600115
RGD:13792537
G LOC303448 similar to glyceraldehyde-3-phosphate dehydrogenase JBrowse link 10 78,687,653 78,696,097 RGD:13792537
G Ogdh oxoglutarate dehydrogenase JBrowse link 14 86,414,924 86,481,903 RGD:1600115
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 JBrowse link 13 47,413,453 47,440,682 RGD:1624291
RGD:1600115
G Pfkl phosphofructokinase, liver type JBrowse link 20 11,393,860 11,415,889 RGD:2301239
RGD:1624291
RGD:2302851
RGD:2302790
RGD:2302736
G Pfkm phosphofructokinase, muscle JBrowse link 7 139,702,066 139,722,132 RGD:1599363
RGD:1624291
RGD:2302736
G Pfkp phosphofructokinase, platelet JBrowse link 17 68,510,765 68,574,387 RGD:2302736
RGD:2302804
G Pgam1 phosphoglycerate mutase 1 JBrowse link 1 261,158,204 261,165,814 RGD:1624291
G Pgam2 phosphoglycerate mutase 2 JBrowse link 14 86,045,005 86,047,116 RGD:1624291
G Pgk1 phosphoglycerate kinase 1 JBrowse link X 77,263,399 77,279,373 RGD:2302859
RGD:13792537
RGD:1600115
RGD:1624291
RGD:2302860
G Pgk2 phosphoglycerate kinase 2 JBrowse link 9 24,095,774 24,097,340 RGD:1624291
RGD:13792537
RGD:1600115
G Pklr pyruvate kinase L/R JBrowse link 2 188,449,158 188,458,034 RGD:2302790
RGD:13792537
RGD:1600115
RGD:2302851
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:2302790
RGD:13792537
RGD:1624291
RGD:12793012
RGD:1600115
RGD:2302804
G Pkm_v1 pyruvate kinase M1/2, variant 1 RGD:1600115
RGD:13792537
RGD:12793012
G Pkm_v2 pyruvate kinase M1/2, variant 2 RGD:1600115
RGD:13792537
RGD:12793012
G Prkag3 protein kinase AMP-activated non-catalytic subunit gamma 3 JBrowse link 9 81,999,368 82,008,620 RGD:1624291
G RGD1559534 similar to Alpha enolase (2-phospho-D-glycerate hydro-lyase) JBrowse link 10 44,658,634 44,662,983 RGD:1600115
G RGD1560402 similar to Phosphoglycerate kinase 1 JBrowse link 2 42,726,747 42,728,100 RGD:1600115
RGD:13792537
G Tpi1 triosephosphate isomerase 1 JBrowse link 4 157,328,375 157,331,905 RGD:1599585
RGD:13792537
RGD:1600115
glycolytic process from galactose term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Galk1 galactokinase 1 JBrowse link 10 104,560,322 104,564,499 RGD:1624291
G Galt galactose-1-phosphate uridylyltransferase JBrowse link 5 58,144,679 58,147,946 RGD:1624291
glycolytic process through fructose-6-phosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pfkl phosphofructokinase, liver type JBrowse link 20 11,393,860 11,415,889 RGD:1624291
G Pfkm phosphofructokinase, muscle JBrowse link 7 139,702,066 139,722,132 RGD:1600115
RGD:1624291
G Pfkp phosphofructokinase, platelet JBrowse link 17 68,510,765 68,574,387 RGD:1600115
lactate biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:1624291
G Ldhc lactate dehydrogenase C JBrowse link 1 102,914,875 102,931,843 RGD:1624291
RGD:1600115
mitochondrial acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpc1 mitochondrial pyruvate carrier 1 JBrowse link 1 53,026,608 53,038,229 RGD:1624291
G Mpc2 mitochondrial pyruvate carrier 2 JBrowse link 13 83,680,527 83,700,491 RGD:1624291
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1624291
negative regulation of glycolytic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 JBrowse link 19 55,438,409 55,510,652 RGD:1624291
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 20 29,509,283 29,511,382 RGD:1624291
RGD:1600115
G Fbp1 fructose-bisphosphatase 1 JBrowse link 17 396,175 417,480 RGD:1600115
RGD:1624291
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:1624291
G Ier3 immediate early response 3 JBrowse link 20 3,438,798 3,440,002 RGD:1624291
G Mtch2 mitochondrial carrier 2 JBrowse link 3 79,678,141 79,695,356 RGD:1624291
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:9686132
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:1624291
RGD:1600115
G Nupr1 nuclear protein 1, transcriptional regulator JBrowse link 1 194,767,484 194,769,519 RGD:1600115
RGD:1624291
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:1624291
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:7242186
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1624291
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
G Tigar TP53 induced glycolysis regulatory phosphatase JBrowse link 4 159,635,145 159,654,108 RGD:1624291
RGD:13792537
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) JBrowse link 10 90,296,144 90,312,401 RGD:1624291
RGD:1600115
positive regulation of glycolytic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 JBrowse link 6 108,087,677 108,123,811 RGD:1624291
RGD:1600115
G Esrrb estrogen-related receptor beta JBrowse link 6 110,360,940 110,458,406 RGD:12910990
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:2301905
G Gpd1 glycerol-3-phosphate dehydrogenase 1 JBrowse link 7 141,368,928 141,377,931 RGD:1624291
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1624291
RGD:1600115
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1642010
G Mlxipl MLX interacting protein-like JBrowse link 12 24,590,645 24,619,639 RGD:1624291
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:7207891
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
RGD:1600115
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:8554193
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:8554193
G Prxl2c peroxiredoxin like 2C JBrowse link 17 1,798,224 1,830,011 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Slc4a4 solute carrier family 4 member 4 JBrowse link 14 20,476,258 20,817,042 RGD:1624291
RGD:1600115
G Zbtb20 zinc finger and BTB domain containing 20 JBrowse link 11 62,014,925 62,561,113 RGD:1624291
pyruvate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase JBrowse link 9 100,281,339 100,291,292 RGD:1599457
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 JBrowse link 1 261,291,742 261,319,743 RGD:1624291
G Pklr pyruvate kinase L/R JBrowse link 2 188,449,158 188,458,034 RGD:2302789
RGD:2302790
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:2302790
G Sds serine dehydratase JBrowse link 12 41,620,429 41,627,741 RGD:1600115
RGD:1624291
G Srr serine racemase JBrowse link 10 61,756,138 61,772,327 RGD:1624291
RGD:13792537
pyruvate oxidation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdk1 pyruvate dehydrogenase kinase 1 JBrowse link 3 58,530,870 58,561,494 RGD:1600115
RGD:1624291
G Pdk2 pyruvate dehydrogenase kinase 2 JBrowse link 10 82,838,270 82,852,758 RGD:1600115
RGD:1624291
G Pdk3 pyruvate dehydrogenase kinase 3 JBrowse link X 62,836,131 62,904,114 RGD:1624291
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:1600115
RGD:1624291
regulation of glycolytic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eif6 eukaryotic translation initiation factor 6 JBrowse link 3 151,356,867 151,363,201 RGD:1600115
RGD:1624291
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Il3 interleukin 3 JBrowse link 10 39,620,535 39,622,973 RGD:1624291
G Jmjd8 jumonji domain containing 8 JBrowse link 10 15,195,954 15,198,870 RGD:1600115
RGD:1624291
G Mlxipl MLX interacting protein-like JBrowse link 12 24,590,645 24,619,639 RGD:634534
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 JBrowse link 17 70,632,778 70,713,736 RGD:729510
G Pgam1 phosphoglycerate mutase 1 JBrowse link 1 261,158,204 261,165,814 RGD:1624291
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 JBrowse link 4 6,559,153 6,799,888 RGD:1624291
G Slc2a6 solute carrier family 2 member 6 JBrowse link 3 5,567,729 5,575,144 RGD:1624291
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
G Zbtb7a zinc finger and BTB domain containing 7a JBrowse link 7 11,429,266 11,446,119 RGD:1600115
RGD:1624291
regulation of pyruvate kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jmjd8 jumonji domain containing 8 JBrowse link 10 15,195,954 15,198,870 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      cellular metabolic process 10737
        organic acid metabolic process 1053
          oxoacid metabolic process 1026
            carboxylic acid metabolic process 979
              monocarboxylic acid metabolic process 642
                pyruvate metabolic process 146
                  L-alanine biosynthetic process from pyruvate 0
                  L-cysteine catabolic process to pyruvate + 0
                  acetyl-CoA biosynthetic process from pyruvate + 13
                  glucose catabolic process to pyruvate + 8
                  glycerol biosynthetic process from pyruvate 1
                  glycolytic process + 119
                  isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway + 0
                  lactate biosynthetic process from pyruvate + 2
                  protocatechuate catabolic process, meta-cleavage 0
                  pyruvate biosynthetic process + 6
                  pyruvate catabolic process + 0
                  pyruvate oxidation 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.