Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:pentose-phosphate shunt
go back to main search page
Accession:GO:0006098 term browser browse the term
Definition:The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).
Synonyms:exact_synonym: hexose monophosphate pathway;   pentose phosphate pathway
 xref: KEGG_PATHWAY:00030;   MIPS_funcat:02.07;   MetaCyc:PENTOSE-P-PWY;   Reactome:R-HSA-71336 "Pentose phosphate pathway (hexose monophosphate shunt), Homo sapiens";   Wikipedia:Pentose_phosphate_pathway


show annotations for term's descendants       view all columns           Sort by:
 
pentose-phosphate shunt term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:1599574
RGD:1624291
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) JBrowse link 5 166,994,683 167,030,441 RGD:1624291
G Kif1b kinesin family member 1B JBrowse link 5 165,994,803 166,133,497 RGD:1600115
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:1599574
RGD:1600115
G Pgls 6-phosphogluconolactonase JBrowse link 16 20,020,444 20,025,930 RGD:1624291
RGD:1600115
G Rpe ribulose-5-phosphate-3-epimerase JBrowse link 9 73,687,684 73,713,643 RGD:1599574
RGD:1624291
G Rpia ribose 5-phosphate isomerase A JBrowse link 4 98,568,028 98,593,664 RGD:1599574
G Taldo1 transaldolase 1 JBrowse link 1 214,375,555 214,385,886 RGD:1599574
G Tkt transketolase JBrowse link 16 6,609,670 6,634,608 RGD:1599574
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpe ribulose-5-phosphate-3-epimerase JBrowse link 9 73,687,684 73,713,643 RGD:1641816
RGD:13792537
G Rpia ribose 5-phosphate isomerase A JBrowse link 4 98,568,028 98,593,664 RGD:1641816
RGD:13792537
G Shpk sedoheptulokinase JBrowse link 10 59,765,328 59,789,676 RGD:1624291
G Taldo1 transaldolase 1 JBrowse link 1 214,375,555 214,385,886 RGD:1641803
RGD:13792537
RGD:1641816
G Tkt transketolase JBrowse link 16 6,609,670 6,634,608 RGD:1580394
RGD:1641816
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:1641793
RGD:1624291
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) JBrowse link 5 166,994,683 167,030,441 RGD:1624291
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:1641793
RGD:13792537
RGD:1624291
G Pgls 6-phosphogluconolactonase JBrowse link 16 20,020,444 20,025,930 RGD:2311501
RGD:13792537
regulation of pentose-phosphate shunt term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 13 111,946,626 111,996,536 RGD:1625062
G Pgam1 phosphoglycerate mutase 1 JBrowse link 1 261,158,204 261,165,814 RGD:1624291
G Tigar TP53 induced glycolysis regulatory phosphatase JBrowse link 4 159,635,145 159,654,108 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      NADP metabolic process 36
        NADPH regeneration 15
          pentose-phosphate shunt 14
            negative regulation of pentose-phosphate shunt 1
            pentose-phosphate shunt, non-oxidative branch 5
            pentose-phosphate shunt, oxidative branch 4
            positive regulation of pentose-phosphate shunt 0
            regulation of pentose-phosphate shunt + 4
Path 2
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      cellular metabolic process 10566
        phosphorus metabolic process 3214
          phosphate-containing compound metabolic process 3194
            glucose 6-phosphate metabolic process 24
              pentose-phosphate shunt 14
                negative regulation of pentose-phosphate shunt 1
                pentose-phosphate shunt, non-oxidative branch 5
                pentose-phosphate shunt, oxidative branch 4
                positive regulation of pentose-phosphate shunt 0
                regulation of pentose-phosphate shunt + 4
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.