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Term:glycerophosphate shuttle
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Accession:GO:0006127 term browser browse the term
Definition:The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
Synonyms:xref: MetaCyc:PWY-6118

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glycerophosphate shuttle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GPD1 glycerol-3-phosphate dehydrogenase 1 JBrowse link 12 50,104,008 50,111,313 RGD:2290271
G GPD2 glycerol-3-phosphate dehydrogenase 2 JBrowse link 2 156,435,290 156,586,403 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18019
    metabolic process 11613
      NADH metabolic process 43
        NADH oxidation 4
          glycerophosphate shuttle 2
Path 2
Term Annotations click to browse term
  biological_process 18019
    cellular process 16998
      cellular metabolic process 10894
        generation of precursor metabolites and energy 546
          energy derivation by oxidation of organic compounds 289
            cellular respiration 190
              respiratory electron transport chain 116
                glycerophosphate shuttle 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.