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Term:glycerophosphate shuttle
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Accession:GO:0006127 term browser browse the term
Definition:The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
Synonyms:xref: MetaCyc:PWY-6118

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glycerophosphate shuttle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) JBrowse link 15 99,717,587 99,725,014 RGD:2290270
G Slc37a2 solute carrier family 37 (glycerol-3-phosphate transporter), member 2 JBrowse link 9 37,229,149 37,255,738 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23101
    metabolic process 10604
      NADH metabolic process 30
        NADH oxidation 6
          glycerophosphate shuttle 2
Path 2
Term Annotations click to browse term
  biological_process 23101
    cellular process 16746
      cellular metabolic process 9566
        generation of precursor metabolites and energy 402
          energy derivation by oxidation of organic compounds 251
            cellular respiration 159
              respiratory electron transport chain 82
                glycerophosphate shuttle 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.